Medical Center  

  HEADDr CONSIGNY Paul Henri /
  MEMBERSDr BEHILLIL Sylvie / Dr BENABDELMOUMEN Ghania / Dr BIARDEAU Brigitte / Dr (medical staff) BICLET Philippe / Dr BODILIS Hélène / Dr BOSSI Philippe / Dr BRUNET-MORET Marie-José / Dr CATHERINOT Emilie / Dr CESSOT Gilles / Dr CHARLIER-WOERTHER Caroline / Dr COLAS-DES-FRANCS Véronique / Dr CONSIGNY Paul Henri / Dr CONSIGNY Sophie / Dr DARIE Hervé / Dr DEMANTKE Anne / Prof. DUPONT Bertrand / Dr DUPONT Patricia / Dr DUVIVIER Claudine / Dr ELOIT-TALMAIN Corinne / Dr GACHOT Bertrand / Dr GERGELY Anna / Dr GOESCH Julia / Dr GOUDAL Maryvonne / Dr GOUJON Catherine / Dr GUINNEPAIN Marie-Thérèse / Dr KALABOKA Sofia / Dr KRAINIK Claire / Dr LANTERNIER Fanny / Dr LAURENT Jérome / Prof. LECUIT Marc / Dr LEGUERN Anne-Sophie / Dr LHERITIER BARRAND Michèle / Prof. LORTHOLARY Olivier / Dr MALKIN Jean-Elie / Dr MAURY-GEDOUX Marie-Pierre / Dr MECHAI Frédéric / Dr MOUAS Houria / Dr NASSIF Aude / Dr PAYS Jean-François / Dr PELICOT Marie / Dr POLLINI Guiseppe / Dr POUJOL Philippe / Dr RIBADEAU-DUMAS Florence / Dr ROTIVEL Yolande / Dr SADORGE Christine / Dr SANMIGUEL Marcela / Dr SIMONS DE FANTI Angèle / Dr THEVENOT Jacques / Dr THEZE Jacques / Dr VAN DER VLIET Diane / Dr WYPLOSZ Benjamin

  Annual Report

The medical center of the Institut Pasteur (MCIP) is the only public health entity in direct contact with the public, through its vaccination center, its consultations and its laboratory. The traditional activities of the MCIP are clinical, in two main domains : (i) infectious diseases and travel medicine, (ii) allergology. The three principal goals of a medical doctor are represented : mainly medical activity, but also clinical research and teaching.

Infectious and tropical diseases, travel medicine

The main medical orientation is travel medicine, with (i) vaccination and travel advice prior to departure, particularly for immunocompromised patients, and (ii) imported post travel diseases (mainly infectious and tropical), including malaria (15-30 cases/year), other vector borne diseases (dengue, etc.), infectious diarrheas and other infections of digestive origin, skin diseases (cutaneous larva migrans, myasis, etc.), etc.

Other key orientations include : (i) HIV infection, in close collaboration with the Necker university hospital via the Necker Pasteur Infectious Diseases Center, (ii) other cosmopolitan infectious diseases (Lyme disease, etc.), (iii) rabies treatment, and (iv) “infectious” dermatology, with a particular focus on hidradenitis suppurativa.


The medical emphasis is on general allergology, both diagnostic and therapeutic. Key interests are : (i) atopic dermatitis, (ii) hereditary angioneurotic edema, with the most important cohort in France.

Clinical Research

Clinical research, as investigator or coordinator (*), is directly connected to the medical orientations of the MCIP : diagnosis (evaluation of rapid diagnostic tests in imported malaria), physiopathology (genetic basis of inflammation abnormalities in hydradenitis suppurativa, A Nassif*), epidemiology (study of antirabies immunity in the field in Brasil, Y Rotivel*; study on travel medicine in the HIV infected patient), respectively in collaboration with Bichat university hospital, Madrid university hospital (Spain), Belem university (Brasil), Avicenne university hospital. Projects on HIV infection are in preparation.

Keywords: Travel medicine, vaccination, tropical medicine, infectious diseases, HIV infection, hidradenitis suppurativa, rabies post-exposure treatment, allergy, angioneurotic edema



Briand V, Buffet P, Genty S, Lacombe K, Godineau N, Salomon J, Vandemelbrouck E, Ralaimazava P, Goujon C, Matheron S, Fontanet A, Bouchaud O. 2006. Absence of efficacy of nonviable Lactobacillus acidophilus for the prevention of traveler's diarrhea : a randomized, double-blind, controlled study. Clin Infect Dis 43(9): 1170-75

Consigny PH, Rolain JM, Mizzi D, Raoult D. 2005. African tick-bite fever in french travelers. Emerg Infect Dis11: 1804-06

Gergely A, Béchet S, Goujon C, Pelicot M, Van der Vliet D, Simons de Fanti A, Benabdelmoumen G, Stumpf P, Augier G, Sadorge C, Consigny PH. 2008. La couverture vaccinale contre le tétanos, la poliomyélite et la diphtérie en 2006 dans une population âgée francilienne. Bulletin Epidémiologique Hebdomadaire 9 : 61-64

LeGoff J, Weiss HA, Gresenguet G, Nzambi K, Frost E, Hayes RJ, Mabey DC, Malkin JE, Mayaud P, Belec L. 2007. Cervicovaginal HIV-1 and herpes simplex virus type 2 shedding during genital ulcer disease episodes. AIDS21(12):1569-78

Morizot G, Delgiudice P, Caumes E, Laffitte E, Marty P, Dupuy A, Sarfati C, Hadj-Rabia S, Darié H,Le Guern AS, Ben Salah A, Pratlong F, Dedet JP, Grögl M,Buffet PA. 2007. Healing of old world cutaneous leishmaniasis in travelers treated with fluconazole : drug effect or spontaneous evolution? Am J Trop Med Hyg 76(1):48-52

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Activity Reports 2009 - Institut Pasteur
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