Medical Center  

  HEADDr CONSIGNY Paul Henri /
  MEMBERSDr AUGIER Ghislaine / Dr BEHILLIL Sylvie / Dr BENABDELMOUMEN Ghania / Dr BIARDEAU Brigitte / Dr BICLET Philippe / Dr BUFFET Pierre / Dr CESSOT Gilles / Dr CHANDESRIS Marie-Olivia / Dr COLAS-DES-FRANCS Véronique / Dr CONSIGNY Paul Henri / Dr CONSIGNY Sophie / Dr DARIE Hervé
Dr DEMANTKE Anne / Prof. DUPONT Bertrand / Dr DUPONT Patricia / Dr DUVIVIER Claudine / Dr ELOIT-TALMAIN Corinne / Dr GACHOT Bertrand / Dr GERGELY Anna / Dr GOESCH Julia / Dr GOUDAL Maryvonne / Dr GOUJON Catherine / Dr GUINNEPAIN Marie-Thérèse
Dr KRAINIK Claire / Dr LAURENT Jérome / Prof. LECUIT Marc / Dr LEGUERN Anne-Sophie / Dr LHERITIER BARRAND Michèle / Prof. LORTHOLARY Olivier / Dr MALKIN Jean-Elie / Dr MECHAI Frédéric / Dr MICOL Romain / Dr MOUAS Houria / Dr NASSIF Aude
Dr PAYS Jean François / Dr PELICOT Marie / Dr POLLINI Guiseppe / Dr POUJOL Philippe / Dr RAFFART Michèle / Dr RIBADEAU-DUMAS Florence / Dr ROTIVEL Yolande / Dr SADORGE Christine / Dr SIMONS DE FANTI Angèle / Dr STUMPF Philip
Dr THEVENOT Jacques / Dr VAN DER VLIET Diane / Dr WYPLOSZ Benjamin

  Annual Report

The medical center of the Institut Pasteur (MCIP) is the only public health entity in direct contact with the public, through its vaccination center, its consultations and its laboratory. The traditional activities of the MCIP are clinical, in two main domains : (i) infectious diseases and travel medicine, (ii) allergology. The three principal goals of a medical doctor are represented : mainly medical activity, but also clinical research and teaching.

Infectious and tropical diseases, travel medicine

The main medical orientation is travel medicine, with (i) vaccination and travel advice prior to departure, particularly for immunocompromised patients, and (ii) imported post travel diseases (mainly infectious and tropical), including malaria (15-30 cases/year), other vector borne diseases (rickettsiosis, dengue, chikungunya etc.), infectious diarrheas and other infections of digestive origin, skin diseases (cutaneous larva migrans, cutaneous leishmaniasis, etc.), etc.

Other key orientations include : (i) HIV infection, in close collaboration with the Necker university hospital via the Necker Pasteur Infectious Diseases Center, (ii) other cosmopolitan infectious diseases (Lyme disease, etc.), (iii) rabies treatment, and (iv) “infectious” dermatology, with a particular focus on hidradenitis suppurativa.


The medical emphasis is on general allergology, both diagnostic and therapeutic. Key interests are : (i) atopic dermatitis, (ii) hereditary angioneurotic edema, with the most important cohort in France.

Clinical Research

Clinical research, as investigator or coordinator (*), is directly connected to the medical orientations of the MCIP : diagnosis (evaluation of rapid diagnostic tests in imported malaria), physiopathology (genetic basis of inflammation abnormalities in hydradenitis suppurativa, A Nassif*), epidemiology (study of antirabies immunity in the field in Brasil, Y Rotivel*; study on travel medicine in the HIV infected patient; study on problems encountered by pilgrims during Mecca pilgrimage, C Goujon*), therapeutics (treatment of acute attacks of hereditary angioedema), respectively in collaboration with Bichat university hospital, Madrid university hospital (Spain), Belem university (Brasil), Avicenne university hospital, French Society of Travel Medicine, and pharmaceutical industry.



Briand V, Buffet P, Genty S, Lacombe K, Godineau N, Salomon J, Vandemelbrouck E, Ralaimazava P, Goujon C, Matheron S,Fontanet A, Bouchaud O. 2006. Absence of efficacy of nonviable Lactobacillus acidophilus for the prevention of traveler's diarrhea : a randomized, double-blind, controlled study. Clinical Infectious Diseases 43 :1170-75 .

Consigny PH, Rolain JM, Mizzi D, Raoult D. 2005. African tick-bite fever in french travelers. Emerging Infectious Diseases 11: 1804-06 .

Van der Vliet DLe Guern AS, Fraitag S, Gounod N, Therby A, Darie H,Buffet PA. 2006. Pseudomonas aeruginosa otochondritis complicating cutaneous leishmaniasis : prevention of mutilation by early antibiotic therapy. Am J Trop Med Hyg 75 : 270-272 .

Morizot G, Delgiudice P, Caumes E, Laffitte E, Marty P, Dupuy A, Sarfati C, Hadj-Rabia S, Darié H, Le Guern AS, Ben Salah A, Pratlong F, Dedet JP, Grögl M, Buffet PA. 2007.Outcome of old world cutaneous leishmaniasis in travelers treated with fluconazole : drug effect or spontaneous healing ? Am J Trop Med Hyg 76 : 48-52 .

Nassif A. 2006. Hidradenitis suppurativa : associated diseases. Causality or complications in Hidradenitis suppurativa. In Jemec G, Revuz J, Leyden JJ. Springer, chapter 6 .

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Activity Reports 2007 - Institut Pasteur
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