Unit: Genomics (Platform)
Director: Bouchier Christiane
Genomic platform (PF1) realize large-scale projects with several teams of Pasteur Institute as part of Genopole programm on Microbiology initiated by the Ministry of Education and Research. Genomic projects have been selected by a steering committee. These projects have been realized following a automation-based protocol. Genomic Platform belongs to Structure and dynamic of genomes department.
Projetcs realized in 2005
Partial genome sequencing of a brasilian strain of Mycobacterium leprae
Nadine Honoré – Unité de Génétique moléculaire bactérienne
Genome sequencing of Streptococcus gallolyticus NEM2135
Patrick Trieu-Cuot– Laboratoire mixte IP-Necker de recherche sur les streptocoques et streptococcies
Low coverage genome sequencing of six strains of yeast
Cécile Fairhead – Unité de Génétique moléculaire des levures
MLST fo strains of Candida albicans
Marie-Elisabeth Bougnoux – Unité postulante Biologie et Pathogénicité fongiques
Allelic diversity of Toll-like receptor family
Luis Quintana-Murci – Unité de prévention et thérapies moléculaires
Current projects
Molecular typing of CIP Bacteria strains
Chantal Bizet – Collection
Allelic diversity of Plasmodium falciparum
Odile Puijalon – Unité d'Immunologie Moléculaire des Parasites
Complete genomic sequence of Microcystis aeruginosa (4,6 Mb)
Nicole Tandeau de Marsac – Unité des Cyanobactéries
Genome sequencing of Leptospira biflexa
Mathieu Picardeau – Unité de Bactériologie moléculaire et médicale
Genome sequencing of Helicobacter pylori (associée à un lymphome du MALT)
Agnés Labigne – Unité de Pathogénie bactérienne des muqueuses
Genome sequencing of E. coli 55989 (collaboration with Genoscope)
Chantal le Bouguenec – Unité de Pathogénie bactérienne des muqueuses
Keywords: High-throughput sequencing, Genome, Sequence analysis