Genopole / Plates-formes / PF1 - Génomique / Publications



Parallel independent evolution of pathogenicity within the genus Yersinia.

Reuter S, Connor TR, Barquist L, Walker D, Feltwell T, Harris SR, Fookes M, Hall ME, Petty NK, Fuchs TM, Corander J, Dufour M, Ringwood T, Savin C, Bouchier C, Martin L, Miettinen M, Shubin M, Riehm JM, Laukkanen-Ninios R, Sihvonen LM, Siitonen A, Skurnik M, Falcão JP, Fukushima H, Scholz HC, Prentice MB, Wren BW, Parkhill J, Carniel E, Achtman M, McNally A, Thomson NR. Proc Natl Acad Sci U S A. 2014 Apr 21.

Bacillus Calmette-Guérin Strain Differences Have an Impact on Clinical Outcome in Bladder Cancer Immunotherapy.

Rentsch CA, Birkhäuser FD, Biot C, Gsponer JR, Bisiaux A, Wetterauer C, Lagranderie M, Marchal G, Orgeur M, Bouchier C, Bachmann A, Ingersoll MA, Brosch R, Albert ML, Thalmann GN. Eur Urol. 2014 Mar 12. pii: S0302-2838(14)00190-0. doi: 10.1016/j.eururo.2014.02.061.

Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity.

Bécavin C, Bouchier C, Lechat P, Archambaud C, Creno S, Gouin E, Wu Z, Kühbacher A, Brisse S, Pucciarelli MG, García-del Portillo F, Hain T, Portnoy DA, Chakraborty T, Lecuit M, Pizarro-Cerdá J, Moszer I, Bierne H, Cossart P. MBio. 2014 Mar 25;5(2):e00969-14. doi: 10.1128/mBio.00969-14.

The Yersinia pseudotuberculosis complex: Characterization and delineation of a new species, Yersinia wautersii.

Savin C, Martin L, Bouchier C, Filali S, Chenau J, Zhou Z, Becher F, Fukushima H, Thomson NR, Scholz HC, Carniel E. Int J Med Microbiol. 2014 Feb 18. pii: S1438-4221(14)00012-5. doi: 10.1016/j.ijmm.2014.02.002.



A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
F Ariey, B Witkowski, C Amaratunga, J Beghain, AC Langlois, N Khim, S Kim, V Duru, C Bouchier, L Ma, P Lim, R Leang, S Duong, S Sreng, S Suon, CM Chuor, D Mey Bout, S Menard, W O Rogers, B Genton, T Fandeur, O Miotto, P Ringwald, J Le Bras, A Berry, JC Barale, R M. Fairhurst, F Benoit-Vical, O Mercereau-Puijalon, D Menard
Nature 19 dec 2013-  doi:10.1038/nature12876

Val ME, Kennedy SP, Soler-Bistué AJ, Barbe V, Bouchier C, Ducos-Galand M, Skovgaard O, Mazel D.
Fuse or Die : How to survive the loss of Dam in Vibrio cholerae
Mol Microbiol. 2013 Dec 6. doi: 10.1111/mmi.12483

Bouvet P, Ruimy R, Bouchier C, Faucher N, Mazuet C, Popoff MR.
J Clin Microbiol
. 2013 Oct 2.

Pawlik A, Garnier G, Orgeur M, Tong P, Lohan A, Le Chevalier F, Sapriel G, Roux AL, Conlon K, Honoré N, Dillies MA, Ma L, Bouchier C, Coppée JY, Gaillard JL, Gordon SV, Loftus B, Brosch R, Herrmann JL.
Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus.
Mol Microbiol. 2013 Sep 3. doi: 10.1111/mmi.12387.

Gabaldón T, Martin T, Marcet-Houben M, Durrens P, Bolotin-Fukuhara M, Lespinet O, Arnaise S, Boisnard S, Aguileta G, Atanasova R, Bouchier C, Couloux A, Creno S, Almeida Cruz J, Devillers H, Enache-Angoulvant A, Guitard J, Jaouen L, Ma L, Marck C, Neuvéglise C, Pelletier E, Pinard A, Poulain J, Recoquillay J, Westhof E, Wincker P, Dujon B, Hennequin C, Fairhead C.

Comparative genomics of emerging pathogens in the Candida glabrata clade BMC Genomics.2013, 14:623

Cousin S, Clermont D, Creno S, Ma L, Loux V, Bizet C, Bouchier C.
Draft genome sequence of Lactobacillus pasteurii CRBIP 24.76T
Genome Announc. July/August 2013 1:e00662-13.

Cousin S, Creno S, Ma L, Clermont D, Loux V, Bizet C, Bouchier C.
Draft genome sequence of Lactobacillus hominis Strain CRBIP 24.179T, isolated from human intestine
Genome Announc. July/August 2013 1:e00662-13.

Cousin S, Loux V, Ma L, Creno S, Clermont D, Bizet C, Bouchier C.
Draft genome sequences of Lactobacillus equicursoris CIP 110162T and Lactobacillus sp. Strain CRBIP 24.137, isolated from thoroughbred racehorse feces and human urine, respectively
Genome Announc. July/August 2013 1:e00663-13.

Falentin H, Cousin S, Clermont D, Creno S, Ma L, Chuat V , Loux V, Rüdiger P, Bizet C, Bouchier C.
Draft genome sequences of five strains of Lactobacillus acidophilus, Strain CIP 76.13T, isolated from humans, strains CIRM-BIA 442 and CIRM-BIA 445, isolated from dairy products, and strains DSM 20242 and DSM 9126 of unknown origin
Genome Announc. July/August 2013 1:e00658-13.

Angebault C, Djossou F, Abélanet S, Permal E, Ben Soltana M, Diancourt L, Bouchier C, Woerther PL, Catzeflis F, Andremont A, d'Enfert C, Bougnoux ME.
 Candida albicans is not always the preferential yeast colonising humans: a study amongst Wayampi Amerindians
J Infect Dis. 2013 Jul 31

Andriantsoanirina V, Khim N, Ratsimbasoa A, Witkowski B, Benedet C, Canier L, Bouchier C, Tichit M, Durand R, Ménard D.
Plasmodium falciparum Na+/H+ exchanger (pfnhe-1) genetic polymorphism in Indian Ocean malaria-endemic areas.
Am J Trop Med Hyg. 2013 Jan;88(1):37-42. doi: 10.4269/ajtmh.2012.12-0359. Epub 2012 Dec 3.

Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Médigue C, Parkhill J,
Cruveiller S, Brosch R.
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis.
Nat Genet. 2013 Feb;45(2):172-9. doi: 10.1038/ng.2517. Epub 2013 Jan 6.

Guérillot R, Da Cunha V, Sauvage E, Bouchier C, Glaser P.
Modular evolution of TnGBSs, a new family of integrative and conjugative elements associating
insertion sequence transposition, plasmid replication, and conjugation for their spreading.
J Bacteriol. 2013 May;195(9):1979-90. doi: 10.1128/JB.01745-12. Epub 2013 Feb 22.

Savin C, Frangeul L, Ma L, Bouchier C, Moszer I, Carniel E.
Draft Genome Sequence of a Clinical Strain of Yersinia enterocolitica (IP10393) of Bioserotype
4/O:3 from France.
Genome Announc. 2013 Jan;1(1). doi:pii: e00150-12.10.1128/genomeA.00150-12. Epub 2013 Feb 21.

Clavaud C, Jourdain R, Bar-Hen A, Tichit M, Bouchier C, Pouradier F, El Rawadi C, Guillot J, Ménard-Szczebara F, Breton L, Latgé JP, Mouyna I.
Dandruff is associated with disequilibrium in the proportion of the major bacterial and fungal populations colonizing the scalp.
PLoS One. 2013;8(3):e58203. doi: 10.1371/journal.pone.0058203. Epub 2013 Mar 6.

Rosinski-Chupin I, Sauvage E, Mairey B, Mangenot S, Ma L, Da Cunha V, Rusniok C, Bouchier C, Barbe V, Glaser P.
Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage.
BMC Genomics. 2013 Apr 15;14(1):252. doi: 10.1186/1471-2164-14-252.

Joffret ML, Bouchier C, Grandadam M, Zeller H, Maufrais C, Bourhy H, Despres P, Delpeyroux F, Dacheux L.
Genomic characterization of Sebokele virus 1 (SEBV1) reveals a new candidate species among the genus Parechovirus.
J Gen Virol. 2013 Apr 17.

Quereda JJ, Pucciarelli MG, Botello-Morte L, Calvo E, Carvalho F, Bouchier C, Vieira A, Mariscotti JF, Chakraborty T, Cossart P, Hain T, Cabanes D, Garcia-Del Portillo F.
Occurrence of mutations impairing sigma factor B (SigB) function upon inactivation of Listeria monocytogenes genes encoding surface proteins.
Microbiology. 2013 May 8. PubMed PMID: 23657685.


Cousin S, Ma L, Creno S, Clermont D, Loux V, Bizet C, Bouchier C.
Draft genome sequence of Lactobacillus gigeriorum CRBIP 24.85T, isolated from a chicken crop.
J Bacteriol. 2012 Nov;194(21):5973. doi: 10.1128/JB.01427-12.

Martinez-Jéhanne V, Pichn C, du Merle L, Poupel O, Cayet N, Bouchier C, Le Bouguénec C.
Role of the Vpe carbohydrate permease in Escherichia coli urovirulence and fitness in vivo.
Infection and immunity 2012 May 21.

Rosenfeld N, Bouchier C, Courvalin P, Périchon B.
Expression of the Resistance-Nodulation-Cell Division Pump AdeIJK in Acinetobacter baumannii is regulated by AdeN, a TetR-type regulator.
Antimicrobial Agents and Chemotherapy 2012 May 56(5) 2504-10.

Cousin S, Motreff L, Gulat-Okalla ML, Gouyette C, Spröer C, Schumann P, Begaud E, Bouchier C, Clermont D, Bizet C.
Lactobacillus pasteurii sp. nov. and Lactobacillus hominis sp. nov. two novel species.
Int J Syst Evol Microbiol. 2012 Feb 10.

Green B, Bouchier C, Fairhead C, Craig NL, Cormack BP.
Insertion site preference of Mu, Tn5, and Tn7 transposons.
Mob DNA. 2012 Feb 7;3(1):3. [Epub ahead of print]

Legrand E, Yrinesi J, Ekala MT, Péneau J, Volney B, Berger F, Bouchier C, Bertani S, Musset L, Meynard JB, Mercereau-Puijalon O.
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after changing drug policy in French Guiana.
Antimicrob Agents Chemother. 2012 Jan 9. [Epub ahead of print]

Khim N, Kim S, Bouchier C, Tichit M, Ariey F, Fandeur T, Chim P, Ke S, Sum S, Man S, Ratsimbasoa A, Durand R, Ménard D.
Reduced Impact of Pyrimethamine Drug Pressure on Plasmodium malariae Dihydrofolate Reductase Gene.
Antimicrob Agents Chemother. 2012 Feb;56(2):863-8. Epub 2011 Nov 28.

Cousin S, Gulat-Okalla ML, Motreff L, Gouyette C, Bouchier C, Clermont D, Bizet C.
Lactobacillus gigeriorum sp. nov. isolated from chicken crop.
Int J Syst Evol Microbiol. 2012 Feb;62(Pt 2):330-4. Epub 2011 Mar 18.


Andriantsoanirina V, Durand R, Pradines B, Baret E, Bouchier C, Ratsimbasoa A, D Ménard.
  In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum
Malaria J. 2011 vol.10 283.

N Khim, S Siv, S Kim, T Mueller, E Fleischmann , B Singh, Pl Cliff Simon Divis, N Steenkeste, L Duval, C Bouchier , S Duong, F Ariey, D Ménard.
  Plasmodium knowlesi infection in Humans, Cambodia, 2007-2010
Emerging Infectious Diseases 2011 vol.17 No. 10 1900-19002.

Manry J, Laval G, Patin E, Fornarino S, Tichit M, Bouchier C, Barreiro LB, Quintana-Murci L.
Evolutionary genetics evidence of an essential, nonredundant role of the IFN-gamma pathway in protective immunity.
Hum Mutat. 2011 Jun;32(6):633-42.

Manry J, Laval G, Patin E, Fornarino S, Itan Y, Fumagalli M, Sironi M, Tichit M, Bouchier C, Casanova JL, Barreiro LB, Quintana-Murci L.
Evolutionary genetic dissection of human interferons.
J Exp Med. 2011 Dec 19;208(13):2747-59. Epub 2011 Dec 12.

Kim S, Nguon C, Guillard B, Duong S, Chy S, Sum S, Nhem S, Bouchier C, Tichit M, Christophel E, Taylor WR, Baird JK, Menard D.
Performance of the CareStart™ G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening.
PLoS One
. 2011;6(12):e28357. Epub 2011 Dec 2.


Andriantsoanirina V, Ratsimbasoa A, Bouchier C, Tichit M , Jahevitra M, Raherinjafy R, Mercereau-Puijalon O, Durand R, Ménard D.
Chloroquine clinical failures in Plasmodium falciparum Malaria are associated with mutant Pfmdr-1, not Pfcrt in Madagascar .
PloS ONE Oct 2010 5:10 e13281.

Andriantsoanirina V, Ménard D, Rabearimanana S, Hubert V, Bouchier C, Tichit M ,Le Bras J, Durand R.
Association of Microsatellite Variations of Plasmodium falciparum Na+/H+ Exchanger (Pfnhe-1) Gene with Reduced In Vitro Susceptibility to Quinine: Lack of Confirmation in Clinical Isolates from Africa.
Am. J. Trop. Med. Hyg., 82(5), 2010, pp. 782–787.

Jambou R, Martinelli A, Pinto J, Gribaldo S, Legrand E, Niang M, Kim N, Pharath L, Volnay B, Ekala MT, Bouchier C, Fandeur T, Berzosa P, Benito A, Ferreira ID, Ferreira C, Vieira PP, Alecrim MG, Mercereau-Puijalon O, Cravo P.
Geographic structuring of the Plamodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity.
PLoS One. 2010 Feb 25;5(2):e9424.

Bob NS, Diop BM, Renaud F, Marrama L, Durand P, Tall A, Ka B, Ekala MT, Bouchier C, Mercereau-Puijalon O, Jambou R.
Parasite polymorphism and severe malaria in Dakar (Senegal); a west african urban area.
PLoS One. 2010 Mar 23;5(3):e9817

Ménard D, Barnadas C, Bouchier C, Henry-Halldin C, Gray LR, Ratsimbasoa A, Thonier V, Carod JF, Domarle O, Colin Y, Bertrand O, Picot J, King CL, Grimberg BT, Mercereau-Puijalon O, Zimmerman PA.
Plasmodium vivax Clinical Malaria is Commonly Observed in Duffy-negative Malagasy People.
Proc Natl Acad Sci U S A. 2010 Mar30;107(13):5967-71

Andriantsoanirina V, Bouchier C, Tichit M, Jahevitra M, Rabearimanana S, Randrianjafy R, Ratsimbasoa A, Mercereau-Puijalon O, Durand R, Ménard D.
Origins of the recent emergence of Plasmodium falciparum pyrimethamine resistant alleles into Madagascar.
Antimicrob. Agents Chemother. 2010 June 54: 2323-2329.

Thiberge JM, Boursaux-Eude C, Lehours P, Dillies MA, Creno S, Coppee JY, Rouy Z, Lajus A, Ma L, Burucoa C, Ruskone-Foumestraux A, Courillon-Mallet A, De Reuse H, Gomperts Boneca I, Lamarque D, Mégraud F, Delchier JC, Médigue C, Bouchier C, Labigne A, Raymond J.
Array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma.
BMC Genomics 2010 11:368

Cazalet C, Gomez-Valero L, Rusniok C, Lomma M, Dervins-Ravault D, Newton HJ , Sansom F M, Jarraud S, Zidane N, Ma L, Bouchier C, Etienne J, Hartland E L, Buchrieser C.
Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires’ Disease.
PLoS Genet 6(2): e1000851. doi:10.1371. 2010

Rusniok C, Couve E, Da Cunha V, El Gana R, Zidane N, Bouchier C, Poyart C, Leclercq R, Trieu-Cuot P, Glaser P.
Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis.
J Bacteriol. 2010 192:2266-2276.

Michelet L, Carod JF, Rakontondrazaka M, Ma L, Gay F, Dauga C.
The pig tapeworm Taenia solium, the cause of cysticercosis: Biogeographic (temporal and spacial) origins in Madagascar.
Mol Phylogenet Evol. 2010 Jan 20.


Monot M, Honore N, Garnier T, Zidane N, Sherafi D, Paniz-Mondolfi A, Matsuoka M, Taylor GM, Donoghue HD, Bouwman A, Mays S, Watson C, Lockwood D, Khamispour A, Dowlati Y, Jianping S, Rea TH, Vera-Cabrera L, Stefani MM, Banu S, Macdonald M, Sapkota BR, Spencer JS, Thomas J, Harshman K, Singh P, Busso P, Gattiker A, Rougemont J, Brennan PJ, Cole ST.
Comparative genomic and phylogeographic analysis of Mycobacterium leprae.
Nat Genet. 2009 Dec;41(12):1264-6.

Solis CF, Santi-Rocca J, Perdomo D, Weber C, Guillén N.
Use of bacterially expressed dsRNA to downregulate Entamoeba histolytica gene expression.
PLoS One. 2009 Dec 23;4(12):e8424.

Andriantsoanirina V, Lascombes V, Ratsimbasoa A, Bouchier C, Hoffman J, Tichit M, Rabarijaona LP, Durand R, Ménard D.
Rapid detection of point mutations in Plasmodiumfalciparumgenes associated with antimalarial drugs resistance by using High-Resolution Melting analysis.
J Microbiol Methods. 2009 Aug78(2):165-70.

Clermont D, Diard S, Bouchier C, Vivier C, Bimet F, Motreff L, Welker M, Kallow W, Bizet C.
Microbacterium binotii sp. nov., isolated from human blood.
Int J Syst Evol Microbiol. 2009 May;59(Pt 5):1016-22.

Le Roux F, Zouine M, Chakroun N, Binesse J, Saulnier D, Bouchier C, Zidane N, Ma L, Rusniok C, Lajus A, Buchrieser C, Médigue C, Polz MF, Mazel D.
Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity.
Environ Microbiol. 2009 Apr 1.

Quach H, Barreiro LB, Laval G, Zidane N, Patin E, Kidd KK, Kidd JR, Veuille M, Antoniewski C, Quintana-Murci L.
Signatures of purifying and local positive selection in human miRNAs.
Am J Hum Genet. 2009 Mar;84(3):316-27.

Ishida K, Welker M, Christiansen G, Cadel-Six S, Bouchier C, Dittmann E, Hertweck C, Tandeau de Marsac N.
Plasticity and evolution of aeruginosin biosynthesis in cyanobacteria.
Appl Environ Microbiol. 2009 Apr;75(7):2017-26.

Dacheux L, Larrous F, Mailles A, Boisseleau D, Delmas O, Biron C, Capek I, Muller M, Ilari F, Lefranc T, Raffi F, Goudal M, Bourhy H.
European bat Lyssavirus transmission among cats, Europe.
Emerg Infect Dis. 2009 Feb;15(2):280-4.

Touchon M, Hoede C, Tenaillon O, Barbe V, Baeriswyl S, Bidet P, Bingen E, Bonacorsi S, Bouchier C, Bouvet O, Calteau A, Chiapello H, Clermont O, Cruveiller S, Danchin A, Diard M, Dossat C, Karoui ME, Frapy E, Garry L, Ghigo JM, Gilles AM, Johnson J, Le Bouguenec C, Lescat M, Mangenot S, Martinez-Jehanne V, Matic I, Nassif X, Oztas S, Petit MA, Pichon C, Rouy Z, Ruf CS, Schneider D, Tourret J, Vacherie B, Vallenet D, Médigue C, Rocha EP, Denamur E.
Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths.
PLoS Genet. 2009 Jan;5(1):e1000344.

Noranate N, Prugnolle F, Jouin H, Tall A, Marrama L, Sokhna C, Ekala MT, Guillotte M, Bischoff E, Bouchier C, Patarapotikul J, Ohashi J, Trape JF, Rogier C, Mercereau-Puijalon O.
Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting.
BMC Microbiol. 2009 Oct 15;9:219.

Steenkeste N, Dillies MA, Khim N, Sismeiro O, Chy S, Lim P, Crameri A, Bouchier C, Mercereau-Puijalon O, Beck HP, Imwong M, Dondorp AM, Socheat D, Rogier C, Coppée JY, Ariey F.
FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug resistance.
Malar J. 2009 Oct 15;8:229.

Bouchier C, Ma L, Créno S, Dujon B, Fairhead C.
Complete mitochondrial genome sequences of three Nakaseomyces species reveal invasion by palindromic GC clusters and considerable size expansion.
FEMS Yeast Res. 2009 Dec;9(8):1283-92.

Andriantsoanirina V, Ratsimbasoa A, Bouchier C, Jahevitra M, Rabearimanana S, Radrianjafy R, Andrianaranjaka V, Randriantsoa T, Rason MA, Tichit M, Rabarijaona LP, Mercereau-Puijalon O, Durand R, Ménard D.
Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.
Antimicrob Agents Chemother. 2009 Nov;53(11):4588-97.

Ivanova EP, Christen R, Bizet C, Clermont D, Motreff L, Bouchier C, Zhukova NV, Crawford RJ, Kiprianova EA.
Pseudomonas brassicacearum subsp. neoaurantiaca subsp. nov., orange-pigmented bacteria isolated from soil and the rhizosphere of agricultural plants.
Int J Syst Evol Microbiol. 2009 Oct;59(Pt 10):2476-81.

Barreiro LB, Ben-Ali M, Quach H, Laval G, Patin E, Pickrell JK, Bouchier C, Tichit M, Neyrolles O, Gicquel B, Kidd JR, Kidd KK, Alcash;s A, Ragimbeau J, Pellegrini S, Abel L, Casanova JL, Quintana-Murci L.
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense.
PLoS Genet. 2009 Jul;5(7):e1000562.

Barnadas C, Musset L, Legrand E, Tichit M, Briolant S, Fusai T, Rogier C, Bouchier C, Picot S, Ménard D.
High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.
Am J Trop Med Hyg. 2009 Jul;81(1):19-22.

Lim P, Alker AP, Khim N, Shah NK, Incardona S, Doung S, Yi P, Bouth DM, Bouchier C, Puijalon OM, Meshnick SR, Wongsrichanalai C, Fandeur T, Le Bras J, Ringwald P, Ariey F.
Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia.
Malar J. 2009 Jan 12;8:11.


Diogo D, Bouchier C, d’Enfert C, Bougnoux ME
Loss of heterozygosity in commensal isolates of the asexual diploid yeast Candida albicans.
Fungal Genet Biol. 2009 Feb;46(2):159-68

Mariette N, Barnadas C, Bouchier C, Tichit M, Ménard D.
Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria.
Malaria Journal 2008 7:219.

Barnadas C, Ratsimbasoa A, Tichit M, Bouchier C, Jahevitra M,Picot S, Ménard D.
Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes.
Antimicrob Agents Chemother. 2008 Vol. 52 No12 4233-4240.

Thierry A, Bouchier C, Dujon B, Richard GF.
Megasatellites: a peculiar class of giant minisatellites in genes involved in cell adhesion and pathogenicity in Candida glabrata.
Nucleic Acids Res. 2008 Oct;36(1):5970-82

Niang M, Marrama L, Ekala MT, Alioune G, Tall A, Ndiaye JL, Sarr D, Dangou JM, Lehesran JY, Bouchier C, Mercereau-Puijalon O, Jambou R.
Accumulation of CVIET Pfcrt allele of Plasmodium falciparum in placenta of pregnant women living in an urban area of Dakar, Senegal.
J Antimicrob Chemother. 2008 Nov;62(5):921-8.

Achour I, Cavelier P, Tichit M, Bouchier C, Lafaye P, Rougeon F.
Tetrameric and homodimeric camelid IgGs originate from the same IgH locus.
J Immunol. 2008 Aug 1;181(3):2001-9.

Cadel-Six S, Dauga C, Castets AM, Rippka R, Bouchier C, Tandeau de Marsac N, Welker M.
Halogenase genes in nonribosomal peptide synthetase gene clusters of Microcystis (cyanobacteria): sporadic distribution and evolution.
Mol Biol Evol. 2008 Sep;25(9):2031-41.

Menard D, Andriantsoanirina V, Jahevitra M, Barnadas C, Tichit M, Bouchier C, Hopkins Sibley C.
Dihydrofolate reductase I164L mutation in Plasmodium falciparum, Madagascar.
Emerg Infect Dis. 2008 Jul;14(7):1166-7.

Frangeul L, Quillardet P, Castets AM, Humbert JF, Matthijs HC, Cortez D,Tolonen A, Zhang CC, Gribaldo S, Kehr JC, Zilliges Y, Ziemert N, Becker S, Talla E, Latifi A, Billault A, Lepelletier A, Dittmann E, Bouchier C, de Marsac NT.
Highly plastic genome of Microcystis aeruginosa PCC 7806, a ubiquitous toxic freshwater cyanobacterium
BMC Genomics. 2008 Jun 5;9:274.

Picardeau M, Bulach DM, Bouchier C, Zuerner RL, Zidane N, Wilson PJ, Creno S, Kuczek ES, Bommezzadri S, Davis JC, McGrathA, Johnson MJ, Boursaux-Eude C, Seemann T, Rouy Z, Coppel RL, Rood JI, Lajus A, Davies JK, Médigue C, Adler B.
Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis.
PLoS ONE. 2008 Feb 13;3(2):e1607.

Barnadas C, Tichit M, Bouchier C, Ratsimbasoa A, Randrianasolo L, Raherinjafy R, Jahevitra M, Picot S, Ménard D.
Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine.
Malar J. 2008 Feb 26;7:35.

Bougnoux ME, Pujol C, Diogo D, Bouchier C, Soll DR, d’Enfert C.
Mating is rare within as well as between clades of the human pathogen Candida albicans.
Fungal Genet Biol. 2008 Mar;45(3):221-31. Epub 2007 Oct 23.

Ziemert N, Ishida K, Quillardet P, Bouchier C, Hertweck C, de Marsac NT, Dittmann E.
Microcyclamide biosynthesis in two strains of Microcystis aeruginosa: from structure to genes and vice versa.
Appl Environ Microbiol. 2008 Mar;74(6):1791-7. Epub 2008 Feb 1.

Zilliges Y, Kehr JC, Mikkat S, Bouchier C, de Marsac NT, Börner T, Dittmann E.
An Extracellular Glycoprotein Is Implicated in Cell-Cell Contacts in the Toxic
Cyanobacterium Microcystis aeruginosa PCC 7806.
J Bacteriol. 2008 Apr;190(8):2871-9. Epub 2008 Feb 15.

Delmas O, Holmes EC, Talbi C, Larrous F, Dacheux L, Bouchier C, Bourhy H.
Genomic diversity and evolution of the lyssaviruses.
. 2008 Apr 30;3(4):e2057.


Ekala MT, Khim N, Legrand E, Randrianarivelojosia M, Jambou R, Fandeur T,
Menard D, Assi SB, Henry MC, Rogier C, Bouchier C, Mercereau-Puijalon O.
Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic
Malar J. 2007 Dec 17;6(1):164

Guljamow A, Jenke-Kodama H, Saumweber H, Quillardet P, Frangeul L, Castets AM,
Bouchier C, Tandeau de Marsac N, Dittmann E.
Horizontal gene transfer of two cytoskeletal elements from a eukaryote to a
Curr Biol. 2007 17(17):R757-9.

Legrand E, Demar M, Volney B, Ekala MT, Quinternet M, Bouchier C, Fandeur T,
Rogier C, Carme B, Puijalon OM, Esterre P.
First case of emergence of atovaquone resistance in Plasmodium falciparum during
second-line atovaquone-proguanil treatment in South America.
Antimicrob Agents Chemother. 2007 51(6):2280-1.

Stinear TP, Seemann T, Pidot S, Frigui W, Reysset G, Garnier T, Meurice G,
Simon D, Bouchier C, Ma L, Tichit M, Porter JL, Ryan J, Johnson PD, Davies JK,
Jenkin GA, Small PL, Jones LM, Tekaia F, Laval F, Daffe M, Parkhill J, Cole ST.
Reductive evolution and niche adaptation inferred from the genome of
Mycobacterium ulcerans, the causative agent of Buruli ulcer.
Genome Res. 2007 17(2):192-200.

Noranate N, Durand R, Tall A, Marrama L, Spiegel A, Sokhna C, Pradines B,
Cojean S, Guillotte M, Bischoff E, Ekala MT, Bouchier C, Fandeur T, Ariey F,
Patarapotikul J, Le Bras J, Trape JF, Rogier C, Mercereau-Puijalon O.
Rapid dissemination of Plasmodium falciparum drug resistance despite strictly
controlled antimalarial use.
PLoS ONE. 2007 2(1):e139.


Kehr JC, Zilliges Y, Springer A, Disney MD, Ratner DD, Bouchier C, Seeberger
PH, de Marsac NT, Dittmann E.
 A mannan binding lectin is involved in cell-cell attachment in a toxic strain of
Microcystis aeruginosa.
Mol Microbiol. 2006 Feb;59(3):893-906.

Ariey F, Fandeur T, Durand R, Randrianarivelojosia M, Jambou R, Legrand E,
Ekala MT, Bouchier C, Cojean S, Duchemin JB, Robert V, Le Bras J,
Mercereau-Puijalon O.
 Invasion of Africa by a single pfcrt allele of South East Asian type.
Malar J. 2006 Apr 26;5:34.

Bougnoux ME, Diogo D, François N, Sendid B, Veirmeire S, Colombel JF, Bouchier
C, Van Kruiningen H, d’Enfert C, Poulain D.
 Multilocus sequence typing reveals intrafamilial transmission and microevolutions
of Candida albicans isolates from the human digestive tract.
J Clin Microbiol. 2006 May;44(5):1810-20.

Weber C, Guigon G, Bouchier C, Frangeul L, Moreira S, Sismeiro O, Gouyette C,
Mirelman D, Coppee JY, Guillén N.
 Stress by heat shock induces massive down regulation of genes and allows
differential allelic expression of the Gal/GalNAc lectin in Entamoeba
Eukaryot Cell. 2006 May;5(5):871-5.

Carré-Mlouka A, Méjean A, Quillardet P, Ashida H, Saito Y, Yokota A,
Callebaut I, Sekowska A, Dittmann E, Bouchier C, de Marsac NT.
 A new rubisco-like protein coexists with a photosynthetic rubisco in the
planktonic cyanobacteria Microcystis.
J Biol Chem. 2006 Aug 25;281(34):24462-71. Epub 2006 May 31.

Louvel H, Bommezzadri S, Zidane N, Boursaux-Eude C, Creno S, Magnier A, Rouy
Z, Médigue C, Saint Girons I, Bouchier C, Picardeau M.
 Comparative and functional genomic analyses of iron transport and regulation in
Leptospira spp.
J Bacteriol. 2006 Nov;188(22):7893-904. Epub 2006 Sep 15.


Talla E, Anthouard V, Bouchier C, Frangeul L, Dujon B.
 The complete mitochondrial genome of the yeast Kluyveromyces thermotolerans.
FEBS Lett. 2005 Jan 3;579(1):30-40.

Grüner AC, Hez-Deroubaix S, Snounou G, Hall N, Bouchier C, Letourneur F,
Landau I, Druilhe P.
 Insights into the P. y. yoelii hepatic stage transcriptome reveal complex
transcriptional patterns.
Mol Biochem Parasitol. 2005 Aug;142(2):184-92.

Pain A, Renauld H, Berriman M, Murphy L, Yeats CA, Weir W, Kerhornou A, Aslett
M, Bishop R, Bouchier C, Cochet M, Coulson RM, Cronin A, de Villiers EP, Fraser
A, Fosker N, Gardner M, Goble A, Griffiths-Jones S, Harris DE, Katzer F, Larke N,
Lord A, Maser P, McKellar S, Mooney P, Morton F, Nene V, O’Neil S, Price C, Quail
MA, Rabbinowitsch E, Rawlings ND, Rutter S, Saunders D, Seeger K, Shah T, Squares
R, Squares S, Tivey A, Walker AR, Woodward J, Dobbelaere DA, Langsley G,
Rajandream MA, McKeever D, Shiels B, Tait A, Barrell B, Hall N.
 Genome of the host-cell transforming parasite Theileria annulata compared with T.
Science. 2005 Jul 1;309(5731):131-3.

Khim N, Bouchier C, Ekala MT, Incardona S, Lim P, Legrand E, Jambou R, Doung
S, Puijalon OM, Fandeur T.
 Countrywide survey shows very high prevalence of Plasmodium falciparum multilocus
resistance genotypes in Cambodia.
Antimicrob Agents Chemother. 2005 Aug;49(8):3147-52.

Jambou R, Legrand E, Niang M, Khim N, Lim P, Volney B, Ekala MT, Bouchier C,
Esterre P, Fandeur T, Mercereau-Puijalon O.
 Resistance of Plasmodium falciparum field isolates to in-vitro artemether and
point mutations of the SERCA-type PfATPase6.
Lancet. 2005 Dec 3;366(9501):1960-3.

Galagan JE, Calvo SE, Cuomo C, Ma LJ, Wortman JR, Batzoglou S, Lee SI,
Bastürkmen M, Spevak CC, Clutterbuck J, Kapitonov V, Jurka J, Scazzocchio C,
Farman M, Butler J, Purcell S, Harris S, Braus GH, Draht O, Busch S, D’Enfert C,
Bouchier C, Goldman GH, Bell-Pedersen D, Griffiths-Jones S, Doonan JH, Yu J,
Vienken K, Pain A, Freitag M, Selker EU, Archer DB, Peñalva MA, Oakley BR, Momany
M, Tanaka T, Kumagai T, Asai K, Machida M, Nierman WC, Denning DW, Caddick M,
Hynes M, Paoletti M, Fischer R, Miller B, Dyer P, Sachs MS, Osmani SA, Birren BW.
 Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and
A. oryzae.
Nature. 2005 Dec 22;438(7071):1105-15.


Cazalet C, Rusniok C, Brüggemann H, Zidane N, Magnier A, Ma L, Tichit M, Jarraud S, Bouchier C, Vandenesch F, Kunst F, Etienne J, Glaser P, Buchrieser C. (2004)
Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity.
Nature Genetics, 305: 1966-1968.

Dujon B, Sherman D, Fischer G, Durrens P, Casaregola S, Lafontaine I, De Montigny J, Marck C, Neuveglise C, Talla E, Goffard N, Frangeul L, Aigle M, Anthouard V, Babour A, Barbe V, Barnay S, Blanchin S, Beckerich JM, Beyne E, Bleykasten C, Boisrame A, Boyer J, Cattolico L, Confanioleri F, De Daruvar A, Despons L, Fabre E, Fairhead C, Ferry-Dumazet H, Groppi A, Hantraye F, Hennequin C, Jauniaux N, Joyet P, Kachouri R, Kerrest A, Koszul R, Lemaire M, Lesur I, Ma L, Muller H, Nicaud JM, Nikolski M, Oztas S, Ozier-Kalogeropoulos O, Pellenz S, Potier S, Richard GF, Straub ML, Suleau A, Swennen D, Tekaia F, Wesolowski-Louvel M, Westhof E, Wirth B, Zeniou-Meyer M, Zivanovic I, Bolotin-Fukuhara M, Thierry A, Bouchier C, Caudron B, Scarpelli C, Gaillardin C, Weissenbach J, Wincker P, Souciet JL. (2004)
Genome evolution in yeasts.
Nature. 430: 35-44.

Kim N, Bouchier C, Ekala MT, Mercereau-Puijalon O, Fandeur T. (2004)
Chemoresistance and polymorphism in falciparum malaria in Cambodia.
Med Mal Infect. 34(Suppl 1): S61-S64. French. No abstract available.

Mlouka A, Comte K, Castets AM, Bouchier C, Tandeau de Marsac N. (2004)
The gas vesicle gene cluster from Microcystis aeruginosa and DNA rearrangements that lead to loss of cell buoyancy.
J Bacteriol. 186: 2355-2365.


Bougnoux ME, Tavanti A, Bouchier C, Gow NA, Magnier A, Davidson AD, Maiden MC, d’Enfert C, Odds FC. (2003)
Collaborative consensus for optimized multilocus sequence typing of Candida albicans.
J Clin Microbiol. 41: 5265-6.

Guillemin I, Bouchier C, Garrigues T, Wisner A, Choumet V. (2003)
Sequences and structural organization of phospholipase A2 genes from Vipera aspis aspis, V. aspis zinnikeri and Vipera berus berus venom. Identification of the origin of a new viper population based on ammodytin I1 heterogeneity.
Eur J Biochem. 270: 2697-706.

Koszul R, Malpertuy A, Frangeul L, Bouchier C, Wincker P, Thierry A, Duthoy S, Ferris S, Hennequin C, Dujon B. (2003)
The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata.
FEBS Lett. 534 :39-48.

Sielaff H, Dittmann E, Tandeau de Marsac N, Bouchier C, Von Dohren H, Borner T, Schwecke T. (2003).
The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase.
Biochem J. 373: 909-16.