Recherche / Départements scientifiques / Microbiologie / Unités et groupes / Biologie des Spirochètes / Publications
Liste des publications
Desvars A, Naze F, Vourc'h G, Cardinale E, Picardeau M, Michault A, Bourhy P. (2012)
Similarities in Leptospira serogroup and species distribution in animals and humans in the Indian Ocean island American Journal of Tropical Medicine and Hygiene (in press)
Lambert A, Picardeau M, Haake DA, Sermswan RW, Srikram A, Adler B, Murray G. (2012)
Infect Immun. (in press)
Slamti L, Picardeau M. (2012)
Methods Mol Biol. 859:169-76.
Bourhy P, Collet L, Lernout T, Zinini F, Hartskeerl RA, van der Linden H, Thiberge JM, Diancourt L, Brisse S, Giry C, Pettinelli F, Picardeau M. (2012)
J Clin Microbiol. 50:307-11.
Slamti L, de Pedro MA, Guichet E, Picardeau M. (2012)
J Bacteriol. 193:6266-75.
Lourdault K, Cerqueira GM, Wunder EA Jr, Picardeau M. (2011)
Infect Immun. 2011 79:3711-7.
Figueira CP, Croda J, Choy HA, Haake DA, Reis MG, Ko AI, Picardeau M. (2011)
BMC Microbiol. ;11:129.
Bourhy P, Bremont S, Zinini F, Giry C, Picardeau M. (2011)
J Clin Microbiol. 49:2154-60.
Hochedez P, Rosine J, Théodose R, Abel S, Bourhy P, Picardeau M, Quénel P, Cabié A. (2011)
Am J Trop Med Hyg. 84:621-6.
Choy HA, Kelley MM, Croda J, Matsunaga J, Babbitt JT, Ko AI, Picardeau M, Haake DA. (2011)
PLoS One. 6:e16879.
Aviat F, Slamti L, Cerqueira GM, Lourdault K, Picardeau M. (2010)
Appl Environ Microbiol. 76:8135-42.
M. Picardeau (2010)
Transposition of fly mariner elements into bacteria as a genetic tool for mutagenesis
Genetica. 138:551-558. (revue)
Transposition of fly mariner elements into bacteria as a genetic tool for mutagenesis
Genetica. 138:551-558. (revue)
A. I. Ko, C. Goarant, and M. Picardeau (2009)
Leptospira: The dawn of the molecular genetics era for an emerging zoonotic pathogen
Nature Rev. Microbiol. 7:736-47 (revue)
Leptospira: The dawn of the molecular genetics era for an emerging zoonotic pathogen
Nature Rev. Microbiol. 7:736-47 (revue)
C. Chassin, M. Picardeau, J.M. Goujon, P. Bourhy, N. Quellard, S. Darche, E. Badell, M.F. d’Andon, N. Winter, S. Lacroix-Lamandé, D. Buzoni-Gatel, A. Vandewalle, and C. Werts (2009)
TLR4- and TLR2-Mediated B Cell Responses Control the Clearance of the Bacterial Pathogen, Leptospira interrogans.
J. Immunol. 183: 2669-2677
TLR4- and TLR2-Mediated B Cell Responses Control the Clearance of the Bacterial Pathogen, Leptospira interrogans.
J. Immunol. 183: 2669-2677
G.M. Cerqueira and M. Picardeau (2009)
A century of Leptospira strain typing.
Infect. Genet. Evol. 9:760-8. (revue)
G.M. Cerqueira, A.J. McBride, M. Picardeau, S.G. Ribeiro, A.N. Moreira, V. Morel, M.G. Reis, A.I. and Ko, O.A. Dellagostin (2009)
Distribution of the Leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospira spp. and application of ligB to typing leptospiral isolates.
J. Med. Microbiol. 58: 1173-1181
F. Xue, J. Yan, and M. Picardeau (2009)
Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes
Microbes Inf. 11:328-33 (revue)
K. Lourdault, F. Aviat, and M. Picardeau (2009)
The use of quantitative PCR to study the dissemination of Leptospira interrogans in the guinea pig infection model of leptospirosis
J. Med. Microbiol. 58:648-55.
A century of Leptospira strain typing.
Infect. Genet. Evol. 9:760-8. (revue)
G.M. Cerqueira, A.J. McBride, M. Picardeau, S.G. Ribeiro, A.N. Moreira, V. Morel, M.G. Reis, A.I. and Ko, O.A. Dellagostin (2009)
Distribution of the Leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospira spp. and application of ligB to typing leptospiral isolates.
J. Med. Microbiol. 58: 1173-1181
F. Xue, J. Yan, and M. Picardeau (2009)
Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes
Microbes Inf. 11:328-33 (revue)
K. Lourdault, F. Aviat, and M. Picardeau (2009)
The use of quantitative PCR to study the dissemination of Leptospira interrogans in the guinea pig infection model of leptospirosis
J. Med. Microbiol. 58:648-55.
G.L. Murray, V. Morel, G.M. Cerqueira, J. Croda, A. Srikram, R. Henry, A.I. Ko, O.A. Dellagostin, D.M. Bulach, R. Sermswan, B. Adler, and M. Picardeau. (2009)
Genome-wide transposon mutagenesis in pathogenic Leptospira spp.
Infect Immun. 77:810-816.
J. Croda, C.P. Figueira, E.A. Jr Wunder, C.S. Santos, M.G. Reis, A. I. Ko, and M. Picardeau (2008)
Targeted mutagenesis in pathogenic Leptospira: Disruption of the ligB gene does not affect virulence in animal models of leptospirosis.
Infect Immun. 76:5826-33.
M. Picardeau, M. Cornet, V. Morel, N. Sertour, D. Chaumet, E. Brachet, and P. Bourhy (2008)
Impact du changement de nomenclature médicale sur le diagnostic et la surveillance de la leptospirose en France
Bulletin Epidémiologique Hebdomadaire / 7octobre 2008 / n°37
P. Ristow, P. Bourhy, S. Kerneis, C. Schmitt, M.-C. Prevost, W. Lilenbaum, and M. Picardeau (2008)
Biofilm Formation by Leptospira strains
Microbiology 154:1309-17.
M. Picardeau (2008)
Conjugative transfer between Escherichia coli and Leptospira spp. as a new genetic tool
Appl Environ Microbiol. 74:319-22.
M. Picardeau, D.M. Bulach, C. Bouchier, R. L. Zuerner, N. Zidane, P. J. Wilson, S. Creno, E. S. Kuczek, S. Bommezzadri, J. C. Davis, A. McGrath, D. Roche, M. J. Johnson, C. Boursaux-Eude, T. Seemann, Z. Rouy, R. L. Coppel, J. I. Rood, A. Lajus, J. K. Davies, C. Médigue, and B. Adler (2008)
Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis
PLoS ONE 3(2):e1607.
H. Louvel, J.-M. Betton, and M. Picardeau (2008)
Heme is necessary to rescue a two-component system mutant strain of Leptospira biflexa
BMC Microbiol. 8(1):25.
H. Louvel, and M. Picardeau (2007)
Genetic manipulation of Leptospira biflexa.
Curr Protoc Microbiol. 2007 Jun;Chapter 12:Unit 12E.4.
P. Ristow, P. Bourhy, F.W. McBride, C.P. Figueira, M. Huerre, P. Ave, I Saint Girons, A.I. Ko, and M. Picardeau (2007)
The OmpA-like protein Loa22 is essential for leptospiral virulence.
PLoS Pathog. 3(7):e97.
Y. Zou, X. Guo, M. Picardeau, H. Xu, and G. Zhao (2007)
A comprehensive survey on isoleucine biosynthesis pathways in seven epidemic Leptospira interrogans reference strains of China.
FEMS Microbiol Lett. 269:90-6.
P. Bourhy, L. Salaün, A. Lajus, C. Medigue, C. Boursaux-Eude, and M. Picardeau (2007)
A genomic island of the pathogen Leptospira interrogans serovar Lai can excise from its chromosome.
Infect Immun. 75:677-83.
H. Louvel, S. Bommezzadri, N. Zidane, C. Boursaux-Eude, S. Creno, A. Magnier, Z. Rouy, C. Médigue, I. Saint Girons, C. Bouchier, and M. Picardeau (2006)
Comparative and functional genomic analyses of iron transport and regulation in Leptospira spp.
J Bacteriol. 188:7893-904.
L. Salaün, F. Mérien, S. Gurianova, G. Baranton, and M. Picardeau (2006)
Application of Multi-Locus Variable number of tandem repeats Analysis for molecular typing of the agent of leptospirosis.
J. Clin. Microbiol. 4:3954-62.
K. Mazouni, G. Pehau-Arnaudet, P. England, P. Bourhy, I. Saint Girons, and M. Picardeau. (2006)
The Scc spirochetal coiled-coil protein forms helical-like filaments and binds to nucleic acids generating nucleoprotein structures.
J. Bacteriol. 188:469-476.
P. Bourhy, L. Frangeul, E. Couvé, P. Glaser, I. Saint Girons, and M. Picardeau (2005)
Complete nucleotide sequence of the LE1 prophage from the spirochete Leptospira biflexa and characterization of its replication and partition functions.
J. Bacteriol. 187:3931-3940.
P. Bourhy, H. Louvel, I. Saint Girons, and M. Picardeau (2005)
Random insertional mutagenesis of Leptospira interrogans, the agent of leptospirosis, using a mariner transposon.
J. Bacteriol. 187:3255-3258.
H. Louvel, I. Saint Girons, and M. Picardeau (2005)
Isolation and characterization of FecA- and FeoB- mediated iron acquisition systems of the spirochete Leptospira biflexa by random insertional mutagenesis.
J. Bacteriol. 187:3249-54
Z. Majed, E. Bellenger, D. Postic, C. Pourcel, G. Baranton, and M. Picardeau (2005)
Identification of variable-number tandem-repeat loci in Leptospira interrogans sensu stricto.
J. Clin. Microbiol. 2005 43:539-545.
M. Picardeau, C. Le Dantec, G.F. Richard, and I. Saint Girons (2003)
The spirochetal chpK-chromosomal toxin-antitoxin locus induces growth inhibition of yeast and mycobacteria.
FEMS Microbiol. Lett. 229: 277-81.
M. Picardeau, H. Bauby, and I. Saint Girons (2003)
Genetic evidence for the existence of two pathways for the biosynthesis of methionine in the Leptospira spp.
FEMS Microbiol. Lett. 225: 257-62.
R. Guégan, J.M. Camadro, I. Saint Girons, and M. Picardeau (2003)
Leptospira spp. possess a complete haem biosynthetic pathway and are able to use exogenous heme sources.
Mol. Microbiol. 49:745-54.
H. Bauby, I. Saint Girons, and M. Picardeau (2003)
Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri.
Microbiology 149 : 689-693.
A.-P. Tchamedeu Kameni, E. Couture-Tosi, I. Saint-Girons, and M. Picardeau (2002)
Inactivation of the spirochete recA gene results in a mutant with low viability and irregular nucleoid morphology.
J. Bacteriol. 184 : 452-458.
M. Picardeau, S. Ren, and I. Saint Girons (2001)
Killing effect and antitoxic activity of the Leptospira interrogans toxin-antitoxin system in Escherichia coli.
J. Bacteriol. 183 : 6494-6497.
I. Saint Girons, A. Brenot, and M. Picardeau (2001)
Genetics of spirochetes- light at the end of the tunnel: response.
Trends Microbiol. 9: 248
M. Picardeau, A. Brenot, and I. Saint Girons (2001)
First evidence for gene replacement in Leptospira spp., inactivation of L. biflexa flaB results in non-motile mutants deficient in endoflagella.
Mol. Microbiol. 40: 189-199.
I. Saint Girons, P. Bourhy, C. Ottone, M. Picardeau, D. Yelton, R.W. Hendrix, P. Glaser, and N. Charon (2000)
The LE1 bacteriophage replicates as a plasmid within Leptospira biflexa. Construction of a L. biflexa-Escherichia coli shuttle vector.
J. Bacteriol. 182: 5700-5705.
Genome-wide transposon mutagenesis in pathogenic Leptospira spp.
Infect Immun. 77:810-816.
J. Croda, C.P. Figueira, E.A. Jr Wunder, C.S. Santos, M.G. Reis, A. I. Ko, and M. Picardeau (2008)
Targeted mutagenesis in pathogenic Leptospira: Disruption of the ligB gene does not affect virulence in animal models of leptospirosis.
Infect Immun. 76:5826-33.
M. Picardeau, M. Cornet, V. Morel, N. Sertour, D. Chaumet, E. Brachet, and P. Bourhy (2008)
Impact du changement de nomenclature médicale sur le diagnostic et la surveillance de la leptospirose en France
Bulletin Epidémiologique Hebdomadaire / 7octobre 2008 / n°37
P. Ristow, P. Bourhy, S. Kerneis, C. Schmitt, M.-C. Prevost, W. Lilenbaum, and M. Picardeau (2008)
Biofilm Formation by Leptospira strains
Microbiology 154:1309-17.
M. Picardeau (2008)
Conjugative transfer between Escherichia coli and Leptospira spp. as a new genetic tool
Appl Environ Microbiol. 74:319-22.
M. Picardeau, D.M. Bulach, C. Bouchier, R. L. Zuerner, N. Zidane, P. J. Wilson, S. Creno, E. S. Kuczek, S. Bommezzadri, J. C. Davis, A. McGrath, D. Roche, M. J. Johnson, C. Boursaux-Eude, T. Seemann, Z. Rouy, R. L. Coppel, J. I. Rood, A. Lajus, J. K. Davies, C. Médigue, and B. Adler (2008)
Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis
PLoS ONE 3(2):e1607.
H. Louvel, J.-M. Betton, and M. Picardeau (2008)
Heme is necessary to rescue a two-component system mutant strain of Leptospira biflexa
BMC Microbiol. 8(1):25.
H. Louvel, and M. Picardeau (2007)
Genetic manipulation of Leptospira biflexa.
Curr Protoc Microbiol. 2007 Jun;Chapter 12:Unit 12E.4.
P. Ristow, P. Bourhy, F.W. McBride, C.P. Figueira, M. Huerre, P. Ave, I Saint Girons, A.I. Ko, and M. Picardeau (2007)
The OmpA-like protein Loa22 is essential for leptospiral virulence.
PLoS Pathog. 3(7):e97.
Y. Zou, X. Guo, M. Picardeau, H. Xu, and G. Zhao (2007)
A comprehensive survey on isoleucine biosynthesis pathways in seven epidemic Leptospira interrogans reference strains of China.
FEMS Microbiol Lett. 269:90-6.
P. Bourhy, L. Salaün, A. Lajus, C. Medigue, C. Boursaux-Eude, and M. Picardeau (2007)
A genomic island of the pathogen Leptospira interrogans serovar Lai can excise from its chromosome.
Infect Immun. 75:677-83.
H. Louvel, S. Bommezzadri, N. Zidane, C. Boursaux-Eude, S. Creno, A. Magnier, Z. Rouy, C. Médigue, I. Saint Girons, C. Bouchier, and M. Picardeau (2006)
Comparative and functional genomic analyses of iron transport and regulation in Leptospira spp.
J Bacteriol. 188:7893-904.
L. Salaün, F. Mérien, S. Gurianova, G. Baranton, and M. Picardeau (2006)
Application of Multi-Locus Variable number of tandem repeats Analysis for molecular typing of the agent of leptospirosis.
J. Clin. Microbiol. 4:3954-62.
K. Mazouni, G. Pehau-Arnaudet, P. England, P. Bourhy, I. Saint Girons, and M. Picardeau. (2006)
The Scc spirochetal coiled-coil protein forms helical-like filaments and binds to nucleic acids generating nucleoprotein structures.
J. Bacteriol. 188:469-476.
P. Bourhy, L. Frangeul, E. Couvé, P. Glaser, I. Saint Girons, and M. Picardeau (2005)
Complete nucleotide sequence of the LE1 prophage from the spirochete Leptospira biflexa and characterization of its replication and partition functions.
J. Bacteriol. 187:3931-3940.
P. Bourhy, H. Louvel, I. Saint Girons, and M. Picardeau (2005)
Random insertional mutagenesis of Leptospira interrogans, the agent of leptospirosis, using a mariner transposon.
J. Bacteriol. 187:3255-3258.
H. Louvel, I. Saint Girons, and M. Picardeau (2005)
Isolation and characterization of FecA- and FeoB- mediated iron acquisition systems of the spirochete Leptospira biflexa by random insertional mutagenesis.
J. Bacteriol. 187:3249-54
Z. Majed, E. Bellenger, D. Postic, C. Pourcel, G. Baranton, and M. Picardeau (2005)
Identification of variable-number tandem-repeat loci in Leptospira interrogans sensu stricto.
J. Clin. Microbiol. 2005 43:539-545.
M. Picardeau, C. Le Dantec, G.F. Richard, and I. Saint Girons (2003)
The spirochetal chpK-chromosomal toxin-antitoxin locus induces growth inhibition of yeast and mycobacteria.
FEMS Microbiol. Lett. 229: 277-81.
M. Picardeau, H. Bauby, and I. Saint Girons (2003)
Genetic evidence for the existence of two pathways for the biosynthesis of methionine in the Leptospira spp.
FEMS Microbiol. Lett. 225: 257-62.
R. Guégan, J.M. Camadro, I. Saint Girons, and M. Picardeau (2003)
Leptospira spp. possess a complete haem biosynthetic pathway and are able to use exogenous heme sources.
Mol. Microbiol. 49:745-54.
H. Bauby, I. Saint Girons, and M. Picardeau (2003)
Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri.
Microbiology 149 : 689-693.
A.-P. Tchamedeu Kameni, E. Couture-Tosi, I. Saint-Girons, and M. Picardeau (2002)
Inactivation of the spirochete recA gene results in a mutant with low viability and irregular nucleoid morphology.
J. Bacteriol. 184 : 452-458.
M. Picardeau, S. Ren, and I. Saint Girons (2001)
Killing effect and antitoxic activity of the Leptospira interrogans toxin-antitoxin system in Escherichia coli.
J. Bacteriol. 183 : 6494-6497.
I. Saint Girons, A. Brenot, and M. Picardeau (2001)
Genetics of spirochetes- light at the end of the tunnel: response.
Trends Microbiol. 9: 248
M. Picardeau, A. Brenot, and I. Saint Girons (2001)
First evidence for gene replacement in Leptospira spp., inactivation of L. biflexa flaB results in non-motile mutants deficient in endoflagella.
Mol. Microbiol. 40: 189-199.
I. Saint Girons, P. Bourhy, C. Ottone, M. Picardeau, D. Yelton, R.W. Hendrix, P. Glaser, and N. Charon (2000)
The LE1 bacteriophage replicates as a plasmid within Leptospira biflexa. Construction of a L. biflexa-Escherichia coli shuttle vector.
J. Bacteriol. 182: 5700-5705.