PUBLICATIONS

 2012

  • 2012-1:        Riederer, I., Negroni, E., Benczel, M., Wolf, A., Aamiri, A., Di Santo, J.P., Silva-Barbosa, S., Butler-Browne, G., Savino, W. and Mouly, V. (2012) Slowing down the differentiation of engrafted human myoblasts into immunodeficient mice correlates with increased proliferation and migration. Molecular Therapy 20:146-154.
  • 2012-2:        Gayraud-Morel, B., Chrétien, F., Negroni, E., Jory, A., Sambasivan, R., Flamant, P., Soubigou, G., Coppée, J.-Y., Di Santo, J., Cumano, A., Mouly, V. and Tajbakhsh, S. (2012) Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells. Journal of Cell Science 125:1738-1749.          
  • 2012-3:        Peaudecerf, L., Lemos, S., Galgano, A., Krenn, G., Vasseur, F., Di Santo, J.P., Ezine, S. and Rocha, B. (2012) Thymocytes may persist and differentiate without any input from bone marrow progenitors. Journal of Experimental Mecidine 209:1401-1408.
  • 2012-4:        Denton, P.W., Nochi, T., Lim, A., Krisko, J.F., Martinez-Torres, F. , Choudhary, S.K., Wahl, A., Olesen, R., Zou, W., Di Santo, J.P., Margolis, D.M. and Garcia, J.V. (2012) IL-2 receptor g-chain molecule is critical for intestinal T-cell reconstitution in humanized mice. Mucosal Immunology 5:555-566.
  • 2012-5:        Redelsperger, F., Lekbaby, B., Mandouri, Y., Giang, E., Duriez, M., Desire, N., Roque Afonso, A.M., Brichler, S., Dubreuil, P., Dobrin, A., Perlemuter, G., Prevot, S., Bacon, N., Grange, J.D., Zatla, F., Le Pendeven, C., Pol, S., Strick-Marchand, H., Di Santo, J., Kremsdorf, D. and Soussan, P. (2012) Production of hepatitis B défective particles is dependent on liver status. Virology 431:21-28. 
  • 2012-6:        Schulthess, J., Meresse, B., Ramiro-Puig, E., Montcuquet, N., Darche, S., Bègue, B., Ruemmele, F., Combadière, C., Di Santo, J.P., Buzoni-Gatel, D. and Cerf-Bensussan, N. (2012) Interleukin-12-dependant NKp46(+) Innate Lymphoid Cells Control Intestinal Inflammation by Recruiting Inflammatory Monocytes. Immunity 37:108-121. 
  • 2012-7:        Lucas, S., Taront, S., Magnan, C., Fauconnier, L., Delacre, M., Macia, L., Delanoye, A., Verwaerde, C., Spriet, C., Saule, P., Goormachtig, G., Héliot, L., Ktorza, A., Movassat, J., Polakowska, R., Auriault, C., Poulain-Godefroy, O., Di Santo, J.P., Froguel, P. and Wolowczuk, I., (2012) Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms. PLoS One 7:e40351.
  • 2012-8:        Waern, J.M., Yuan, Q., Rüdrich, U., Becker, P.D., Schulze, K., Strick-Marchand, H., Huntington, N.D., Zacher BJ, Wursthorn K, Di Santo, J.P., Guzman, C.A., Manns, M.P., Ott, M. and Bock, M. (2012) Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice. Hepatology (in press).
  • 2012-9:        Bencze, M., Negroni, E., Vallese, D., Yacoub–Youssef, H., Chaouch, S., Wolff, A., Aamiri, A., Di Santo, J.P., Chazaud, B. and Butler-Browne, G.S., Savino, W., Mouly, V., and Riederer, I. (2012) Pro-inflammatory macrophages enhance the regenerative capacity of human myoblasts by modifying the kinetics of proliferation and differentiation. Molecular Therapy (in press).


2011
  • Gayraud-Morel, B, Chrétien, F., Negroni, E., Jory, A., Sambasivan, R., Flamant, P., Soubigou, G., Coppée, J.-Y., Di Santo, J., Cumano, A., Mouly, V. and Tajbakhsh, S. (2011) Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells. Journal of Cell Science (in press).
  • Mamchaoui, K., Trollet, C., Bigot, A., Negroni, E., Chaouch, S., Wolff, A., Kandalla, P.K., Marie, S., Di Santo, J.P., Lacau St Guily, J., Muntoni, F., Kim, J., Philippi, S., Spuler, S., Levy, N., Blumen, S.C., Voit, T., Wright, W.E., Aamiri, A., Butler-Browne, G. and Mouly, V. (2011) Immortalized pathological human myoblasts: towards a universal tool for the study of neuromuscular disorders. Skeletal Muscle 1:34.
  • Riederer, I., Negroni, E., Benczel, M., Wolf, A., Aamiri, A., Di Santo, J.P., Silva-Barbosa, S., Butler-Browne, G., Savino, W and Mouly, V. (2011) Slowing down the differentiation of engrafted human myoblasts into immunodeficient mice correlates with increased proliferation and migration. Molecular Therapy (in press).
  • Yusa, K., Rashid, S.T., Strick-Marchand, H., Miranda, E., Ordonez, A., Hannan, N., Rohani, F., Alexander, G., Marciniak, S.J., Gregory, P.D., Di Santo, J.P., Lomas, D.A., Bradley, A. and Vallier, L. (2011) Efficient bi-allelic correction of a1-antitrypsin deficiency in human induced pluripotent stem cells. Nature 478:391-394.
  • Huntington, N.D., Alves, N.L., Legrand, N., Lim, A.M., Strick-Marchand, H., Plet, A., Weijer, K., Jacques, Y., Spits, H. andDi Santo, J.P. (2011) Autonomous and extrinsic regulation of thymopoiesis in human immune system mice. European Journal of Immunology41:2883-2893.
  • Legrand, N., Huntington, N.D., Nagasawa, M., Bakker, A.Q., Schotte, R., Strick-Marchand, H., de Geus, S.J., Pouw, S.M., Bohne, M., Weijer, K., Di Santo, J.P. and Spits, H. (2011) Functional CD47/signal regulatory protein alpha (SIRPá) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo. Proceedings of the National Academy of Sciences (USA) 108:13224-13229.
  • Beuneu, H., Deguine, J., Bouvier, I., Di Santo, J.P., Albert, M.L. and Bousso, P. (2011) A dual role for type I IFNs during poly I:C acid-induced NK cell activation. Journal of Immunology 187:2084-2088.
  • Kollias, G., Papadaki, P., Apparailly, F., Vervoordeldonk, M.J., Holmdahl, R., Baumans, V., Desaintes, C, Di Santo, J., Distler, J., Garside, P., Hegen, M., Huizinga, T., Jungel, A., Klareskog, L., McInnes, I., Ragoussis, I., Schett, G., t’Hart, B., Toes, R., van den Berg, W., Wurst, W. and Gay, S. (2011) Animal models for arthritis: Innovative tools for prevention and therapy. Annals of Rheumatoid Diseases 70:1357-62.
  • Huntington, N.D., Alves, N.L., Legrand, N., Lim, A.M., Strick-Marchand, H., Mention, J.-J., Plet, A., Weijer, K., Jacques, Y., Becker, P.D., Guzman, C.A., Soussan, P., Kremsdorf, D., Spits, H. andDi Santo, J.P. (2011) IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo. Proceedings of the National Academy of Sciences (USA)108:6217-22.
  • Dumontier, L., de Heusch, M., Orabona, C., Satoh-Takayama, N., Eberl, G., Sirard, J.-C., Di Santo, J.P. and Renauld, J.-C. (2011) IL-22 is produced by gc-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. European Journal of Immunology 41:1075-85.
  • Sawa, S., Lochner, M., Satoh-Takayama, N., Gaboriau-Routhiau, V., Dulauroy, S., Berard, M., Cerf-Bensussan, N., Cua, D., Di Santo, J.P. and Eberl, G. (2011) RORgt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nature Immunology 12:320-6.
  • Korbel, D.S., Barakat, F.M., Di Santo, J.P. and McDonald, V. (2011) CD4+ T cells are not essential for control of early acute Cryptosporidium parvum infection in neonatal mice. Infection and Immunity 79:1647-53.
  • Satoh-Takayama, N., Lesjean-Pottier, S., Sawa, S.-I., Vosshenrich, C.A.J., Eberl, G. and Di Santo, J.P. (2011) LTbR-independent development of intestinal IL-22-producing NKp46+ innate lymphoid cells. European Journal of Immunology 41:780-786.
  • Spits, H. and Di Santo, J.P. (2011) The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nature Immunology 12:21-27.
2010
  • Elkabets, M., Gomes-Ribiero, V., Dinarello, C.A., Ostrand-Rosenberg, S., Di Santo, J.P., Apte, R.N. and Vosshenrich, C.A.J. (2010) IL-1b regulates myeloid suppressor cell subsets that inhibit NK cell development and function. European Journal of Immunology 40:3347-3357.
  • Crellin, N., Triafari, S., Kaplan, C., Satoh-Takayama, N., Di Santo, J.P. and Spits, H. (2010) Regulation of cytokine secretion in human CD127+ LTi-like innate lymphoid cells by Toll-like receptor 2. Immunity 33:752-764.
  • Klein Wolterink, R.G.L., Garcia-Ojeda, M.E., Vosshenrich, C.A.J. and Di Santo, J.P. (2010) The intrathymic crossroads of T and NK cell differentiation. Immunological Reviews 238:126-137.
  • Becker, P.D., Legrand, N., van Geelen, C., Noerder, M., Noerder, M., Huntington, N.D., Lim, A., Yasuda, E., Diehl, S., Scheeren, F.A., Ott, M., Weijer, K., Wedemeyer, H., Di Santo J.P., Beaumont, T., Guzman, C.A, and Spits, H. (2010) Generation of human antigen-specific monoclonal IgM antibodies using vaccinated “Human Immune System” mice. PLOS One 5(10). pii: e13137.
  • Deguine, J., Bréart, B., Lemaitre, F., Di Santo, J.P. and Bousso, P. (2010) Intravital imaging reveals distinct dynamics for natural killer and CD8+ T cells during tumor regression. Immunity 33:632-644.
  • Sawa, S., Cherrier, M., Lochner, M., Satoh-Takayama, N., Fehling, H.-J., Langa, F., Di Santo, J.P. and Eberl, G. (2010) Lineage relationship analysis of RORãt+ innate lymphoid cells. Science 330:665-669.
  • Ribeiro, V.S.G., Hasan, M., Wilson, A., Boucontet, L., Pereira, P., Lesjean-Pottier, S., Satoh-Takayama, N., Di Santo, J.P. and Vosshenrich, C.A.J. (2010) Cutting Edge: Thymic NK cells develop independently from T cell precursors. Journal of Immunology 185:4993-4997.
  • Di Santo, J.P. (2010) The innate side of TOX. Nature Immunology 11:885-886.
  • Di Santo, J.P. (2010) An IL-1b-dependent switch for innate mucosal immunity? Immunity 32:734-736.
  • Di Santo, J.P. (2010) Immunology. A guardian of T cell fate. Science 329:44-45.
  • Di Santo, J.P., Vosshenrich, C.A. and Satoh-Takayama, N. (2010) A ‘natural’ way to provide innate mucosal immunity. Current Opinion in Immunology 22:435-441.
  • Alves, N.L., Huntington, N.D., Mention, J.-J., Richard-LeGoff, O. and Di Santo, J.P. (2010) Ctting Edge: A thymocyte-thymic epithelial cell crosstalk dynamically regulates intrathymic IL-7 expression in vivo. Journal of Immunology 184:5949-5953.
  • Decaluwe, H., Taillardet, M., Corcuff, E., Munitic, I., Law, H.K.W., Rocha, B., Rivière, Y. and Di Santo, J.P. (2010) gc deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors. Proceedings of the National Academy of Sciences (USA) 107:9311-9316.
  • Macia, L., Viltart, O., Delacre, M., Sachot, C., Héliot, L., Di Santo, J.P. and Wolowczuk, I. (2010) Interleukin-7, a new cytokine targeting the mouse hypothalamic arcuate nucleus : role in body weight and food intake regulation. PLOS One 5:e9953.
  • Touboul, T., Hannan, N.R., Corbineau, S., Martinez, A., Martinet, C., Branchereau, S., Mainot, S., Strick-Marchand, H., Pedersen, R., Di Santo, J.P., Weber, A., and Vallier, L. (2010) Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development. Hepatology 51:1754-65.
  • Satoh-Takayama, N., Lesjean-Pottier, S., Vieira, P., Sawa, S., Eberl, G., Vosshenrich, C.A. and Di Santo, J.P. (2010) IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors. Journal of Experimental Medicine 207:273-280.
  • Pisani, D.F., Dechesne, C.A., Sacconi, S., Delplace, S., Belmonte, N., Cochet, O., Clement, N., Wdziekonski, B., Villageois, A.P., Butori, C., Bagnis, C., Di Santo, J.P., Kurzenne, J.Y., Desnuelle, C. and Dani, C. (2010) Isolation of a highly myogenic CD34-negative subset of human skeletal muscle cells free of adipogenic potential. Stem Cells 28:753-64.
  • Sellge, G., Magalhaes, J.G., Fritz, J.H., Konradt, C., Tanguy, M., Eberl, G., Bandeira, A., Di Santo, J.P., Sansonetti, P.J. and Phalipon, A. (2010) Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity. Journal of Immunology 184:2076-2085.
 
  • van Lent, A.U., Dontje, W., Nagasawa, M., Siamari, R., Bakker, A.Q., Pouw, S.M., Maijoor, K.A. Weijer, K., Cornelissen, J.J., Blom, B., Di Santo, J.P., Spits, H. and Legrand, N. (2010) IL-7 enhances thymic human T cell development in Human Immune System Rag2-/-IL-2Rgammac-/- mice without affecting peripheral T cell homeostasis. Journal of Immunology 183:7645-7655.
2009
  • Satoh-Takayama, N., Dumontier, L., Lesjean-Pottier, S., Ribeiro, V.S.G., Mandelboim, O., Renauld, J.-C., Vosshenrich, C.A.J., and Di Santo, J.P. (2009) The natural cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium. Journal of Immunology 183:6579-6587.
  • Munitic, I., Decaluwe, H., Evaristo, C., Lemos, S., Wlodarczyk, M., Worth, A., Le Bon, A., Selin, L.K., Rivière, Y., Di Santo, J.P., Borrow, P. and Rocha, B. (2009) Epitope specificity and relative clonal abundance do not affect CD8 T cell differentiation patterns during LCMV infection. Journal of Virology 83:11795-11807.
  • Di Santo, J.P. (2009) A defining factor for NK cell development. Nature Immunology 10:1051-1052.
  • Barakat, F.M., McDonald, V., Di Santo, J.P. and Korbel, D.S. (2009) Roles for NK cells and an NK cell-independent source of intestinal interferon-γ for innate immunity to Cryptosporidium parvum infection. Infection and Immunity 77:5044-5049.
  • Manz, M.G. and Di Santo, J.P. (2009) Meeting Report: Renaissance for mouse models of human hematopoiesis and immunobiology. Nature Immunology 10:1039-1042.
  • Beuneu, H., Deguine, J., Bréart, B., Mandelboim, O., Di Santo, J.P. and Bousso, P. (2009) Dynamic behavior of NK cells during activation in lymph nodes. Blood 114:3227-3234.
  • Alves, N., Huntington, N.D., Rodewald, H.-R. and Di Santo, J.P. (2009) Thymic Epithelial Cells: the multi-tasking framework of the T cell “cradle”. Trend in Immunology 30:468-474.
  • Negroni, E., Riedere, I., Chaouch, S., Belicchi, M., Razini, P., Di Santo, J.P., Torrente, Y., Butler-Browne, G.S. and Mouly, V. (2009) In vivo myogenic potential of human CD133+ muscle-derived stem cells: a quantitative study. Molecular Therapy 17:1771-1778.
  • Haridass, D., Yuan, Q., Becker, P.D., Cantz, T., Iken, M., Narain, N., Bock, M., Nörder, M., Legrand, N., Wedemeyer, H., Weijer, K., Spits, H., Manns, M.P., Cai, J., Deng, H.-K., Di Santo J.P., Guzman, C.A, and Ott, M. (2009) Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells and embryonic stem cell-derived hepatic cells in Alb-uPA mice. American Journal of Pathology 175:1483-1492.
 
  • Vosshenrich, C.A.J., Huntington, N.D., Ribeiro, V.S.G., Satoh-Takayama, N., and Di Santo, J.P. (2009) Development of NK cell diversity. In: Cell Determination during Hematopoiesis (Eds : Geoffrey Brown & Rhodri Ceredig), Nova Science Publishers, Inc. (in press).
  • Chaouch, S., Mouly, V., Goyenvalle, A., Vulin, A., Mamchaoui, K., Negroni, E., Di Santo, J., Butler-Browne, G., Torrente, Y., Garcia, L.and Furling, D. (2009) Immortalized skin fibroblasts expressing conditional MyoD as a renewable and reliable source of converted human muscle cells to assess therapeutic strategies for muscular dystrophies: validation of an exon skipping approach to restore dystrophin in Duchenne Muscular Dystrophy cells. Human Gene Therapy 20:784-790.
  • Legrand, N., Ploss, A., Balling, R., et al. (2009) Humanized mice: modeling human infectious disease : challenges, progress and outlook. Cell Host and Microbe 6:5-9.
  • Goudenege, S., Pisani, D.F., Wdziekonski, B., Di Santo, J.P., Bagnis, C., Dani, C. and Dechesne, C.A. (2009) Enhancement of myogenic and muscle repair capacities of human adipose-derived stem cells with forced expression of MyoD. Molecular Therapy 17:1064-1072.
  • Huntington, N.D., Labi, V., Cumano, A., Vieira, P., Strasser, A., Villunger, A., Di Santo, J.P. and Alves, N.L. (2009) Loss of pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7. International Immunology 21:715-725.
  • Alves, N.L., Richard-Le Goff, O., Huntington, N.D., Sousa, A.P., Ribeiro, V., Bordack, A., Langa Vives, F., Peduto, L., Chidgey, A., Cumano, A., Boyd, R., Eberl, G. and Di Santo, J.P. (2009) Characterization of the thymic IL-7 niche in vivo. Proceedings of the National Academy of Sciences (USA) 106:1512-1517.
  • Huntington, N.D., Legrand, N., Alves, N.L., Jaron, B., Weijer, K., Plet, A., Corcuff, E., Mortier, E., Jacques, Y., Spits, H. andDi Santo, J.P. (2009) IL-15 trans-presentation promotes human NK cell development and terminal differentiation in vivo. Journal of Experimental Medicine 206:25-34.
2008
  • Satoh-Takayama, N., Vosshenrich, C.A.J., Lesjean-Pottier, S.., Sawa, S., Lochner, M., Rattis, F., Mention, J.-J., Thiam, K., Cerf-Bensussan, N., Mandelboim, O., Eberl, G. and Di Santo, J.P. (2008) Microbial flora drives IL-22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29:958-970.
  • Di Santo, J.P. (2008) Functionally distinct NK cell subsets: developmental origins and biological implications. European Journal of Immunology 38:2948-51.
  • Strick-Marchand, H., Masse, G.X. Weiss, M.C. and Di Santo, J.P. (2008) Lymphocytes support oval cell-dependent liver regeneration. Journal of Immunology 181:2764-2771.
  • Dulphy, N., Haas, P., Busson, M., Belhadj, S., de Latour, R.P., Robin, M., Carmagnat, M., Loiseau, P., Tamouza, R., Scieux, C., Rabian, C., Di Santo, J.P., Charron, D., Janin, A., Socié, G. and Toubert, A. (2008) An unusual CD56bright CD16low NK cell subset dominates the early post-transplant period following HLA-matched hematopoietic stem cell transplantion. Journal of Immunology 181:2227-2237.
  • Lochner, M., Peduto, L., Cherrier, M., Sawa, S., Varona, R., Riethmacher, D., Si-Tahar, M., Di Santo, J.P. & Eberl, G. (2008) Equilibrium in vivo of pro-inflammatory IL-17+ and regulatory IL-10+ FoxP3+ RORãt+ T cells. Journal of Experimental Medicine 205:1381-1393.
  • Huntington, N.D. & Di Santo, J.P. (2008) Humanized immune system (HIS) mice as a tool to study human NK cell development. Current Topics in Microbiology and Immunology 324:109-124.
  • Di Santo, J.P. (2008) Natural killer cells: diversity in search of a niche. Nature Immunology 9:473-475.
  • Riederer, I., Negroni, E., Bigot, A., Bencze, M., Di Santo, J., Aamiri, A., Butler-Browne, G., Mouly, V. (2008) Heat shock treatment increases engraftment of transplanted human myoblasts into immunodeficient mice. Transplantation Proceedings 40:624-30.
  • Wang, Y., Kissenpfennig, A., Mingueneau, M., Richelme, S., Perrin, P., Chevrier, S., Genton, C., Lucas, B., Di Santo, J.P., Orbea, H.-A., Malissen, B. and Malissen, M. (2008) Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells. Journal of Immunology 180:1565-75.
  • Silva-Barbosa, S.D., Butler-Browne, G.S., de Mello, W., Riederer I., Di Santo, J.P., Savino, W. and Mouly, V. (2008) Human myoblast engraftment is improved in laminin enriched microenvironment. Transplantation 85:566-575.
2007
  • Vosshenrich, C.A.J., Lesjean-Pottier, S., Hasan, M., Richard-Le Goff, O., Corcuff, O., Mandelboim, O. and Di Santo, J.P. (2007) CD11cloB220+ Interferon-producing killer dendritic cells are activated NK cells. Journal of Experimental Medicine 240:2569-2578.
  • Masse, G.X., Corcuff, E., Strick-Marchand, H., Guy-Grand, D., Tafuri-Bladt, A., Albert, M.L., Lantz, O. and Di Santo, J.P. (2007) gc cytokines condition the progressive differentiation of CD4+ T cells. Proceedings of the National Academy of Sciences (USA) 104:15442-15447.
  • Némati, F., Mathiot, C., Grandjean, I., Lantz, O., Bordier, V., Dewulf, S., Ekue, R., Di Santo, J.P., Poupon, M.-F. and Decaudin, D. (2007) Imatinib mesylate reduces rituximab-induced tumor-growth inhibition in vivo on Epstein-Barr virus-associated human B-cell lymphoma. Anticancer Drugs 18:1029-1037.
  • Masse, G.X., Corcuff, E., Decaluwe, H., Bommhardt, U., Lantz, O., Buer, J. and Di Santo, J.P. (2007) gc cytokines provide multiple homeostatic signals to naïve CD4+ T cells. European Journal of Immunology 37:2606-2616.
  • Huntington, N.D., Vosshenrich, C.A.J., and Di Santo, J.P. (2007) Developmental pathways that generate NK-cell diversity in humans and mice. Nature Reviews Immunology 7:703-714.
  • Zhu, C-H., Mouly, V., Cooper, R.N., Mamchaoui, K., Bigot, A., Shay, J.W., Di Santo, J.P., Butler-Browne, G.S. and Wright, W.E. (2007) Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin- dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies. Aging Cell 6:515-23.
  • Sansonetti, P.J. and Di Santo, J.P. (2007) Debugging how bacteria manipulate the immune response. Immunity 26 :149-61.
2006
  • Decaudin, D., Marszak, F., Couturier, J., Mathiot, C., Martin, A., Némati, F., Lantz, O., Di Santo, J.P., Arnaud, P., Bordier, V., Vincent-Salomon, A. and Poupon, M.-F. (2006) High efficacy of combined rituximab and gemcitabine on EBV-associated human B-cell lymphoma obtained after Hodgkin’s xenograft in immunodeficient mice. Anticancer Drugs 17:685-95.
  • Vosshenrich, C.A.J., García-Ojeda, M.E., Samson-Villeger, S.I., Pasquelleto, V., Enault, L., Richard-Le Goff, O., Corcuff, E., Guy-Grand, D., Rocha, B., Cumano A., Rogge, L., Ezine, S. and Di Santo, J.P. (2006) A thymic pathway of murine natural killer cell development characterized by Gata3 and interleukin-7 receptor expression. Nature Immunology 7:1217-1224.
  • de Latour, R.P., Dujardin, H., Mishellany, F., Burlen-Defranoux, O., Zuber, J., Marques, R., Di Santo, J.P., Cumano, A., Vieira, P. and Bandeira, A. (2006) Ontogeny, function and peripheral homeostasis of regulatory T cells in the absence of interleukin-7. Blood 108:2300-6.
  • Di Santo, J.P. and Vosshenrich, C.A.J. (2006) Bone marrow versus thymic pathways of NK cell development. Immunological Reviews 214:35-46.
  • Parouchev, A., Nguyen, T.H., Dagher, I., Mainot, S., Groyer-Picard, M.T., Branger, J., Gonin, P., Di Santo, J., Franco, D., Gras, G. and Weber, A. (2006) Efficient ex vivo gene transfer into non-human primate hepatocytes using HIV-1 derived lentiviral vectors. Journal of Hepatology 45:99-107.
  • Caraux, A., Lu, Q., Di Santo, J.P., Raulet, D.H., Lemke, G. and Roth, C. (2006) Natural killer cell differentiation driven by Tyro 3 receptor tyrosine kinases. Nature Immunology 7:747-54.
  • Buentke, E., Coles, M., Tolaini, M., Kioussis, D., Di Santo, J.P., Zamoyska, R., and Seddon, B. (2006) Do CD8 effector cells need IL-7R to become resting memory cells ? Blood 108:1949-56.
  • Roland, J., Soulard, V., Sellier, C., Drapier, A.-M., Di Santo, J.P., Cazenave, P.-A. and Pied, S. (2006) NK cell responses to Plasmodium infection and control of intrahepatic parasite development. Journal of Immunology 177:1229-39.
  • Liu, A., Vosshenrich, C.A.J., Lagresle-Peyrou, C., Malassis-Seris, M., Hue, C., Fischer, A., Di Santo, J.P. and Cavazzana-Calvo, M. (2006) Competition within the early B cell compartment conditions B cell reconstitution after hematopoietic stem cell transplantation in non-irradiated recipients. Blood 108:1123-8.
  • Blachère, N.E., Morris, H.K., Braun, D., Saklani, H., Di Santo, J.P., Darnell, R.B. and Albert, M.L. (2006) Interleukin-2 is required for the activation of memory CD8+ T cells via antigen cross-presentation. Journal of Immunology 176:7288-300.
  • Lizundi, R., Chaussepied, M., Huerre, M., Werling, D., Di Santo, J.P. and Langsley, G. (2006) JNK/cJun signalling promotes survival and metastasis of B-lymphocytes transformed by Theileria. Cancer Research 66:6105-10.
  • Rybner-Barnier, C., Jacquemot C., Cuche, C., Doré, G., Majlessi, L., Gabellec, M.-M., Moris, A., Schwartz, O., Di Santo, J.P., Cumano, A., Leclerc, C. and Lazarini, F. (2006) Processing of the BSE-specific prion by dendritic cells. Journal of Virology 80:4656-63.
  • Di Santo, J.P. (2006) Natural Killer Cell Developmental Pathways : A Question of Balance. Annual Review of Immunology 24:257-86.
  • Lambolez, F., Arcangeli, M-L., Joret, A-M., Pasqualetto, V., Cordier, C., Di Santo, J.P., Rocha, B. and Ezine, S. (2006) The thymus exports long-lived fully committed T cell precursors that can colonize lymphoid organs. Nature Immunology 7:76-82.
2005
  • Silva-Barbosa, S.D., Butler-Browne, G.S., Di Santo, J.P. and Mouly, V. (2005) Comparative analysis of genetically-engineered immunodeficient mouse strains as recipients for human myoblast transplantation. Cell Transplantation 14 :457-67.
  • Feuillet, V., Lucas, B., Di Santo, J.P., Bismuth, G. and Trautmann, A. (2005) Multiple survival signals are delivered by dendritic cells to naïve T cells. European Journal of Immunology 35:2563-72.
  • Le Barillec, K., Gamelas, J., Corcuff, E., Thuizat, A., Sansonetti, P.J., Phalipon, A. and Di Santo, J.P. (2005) Roles for T and NK cells in the innate immune response to Shigella flexneri. Journal of Immunology 175:1735-40.
  • Ranson, T., Bregenholt, S., Lehuen, A., Gaillot, O., Leite-de-Moraes, M.C., Herbelin, A., Berche, P. and Di Santo, J.P. (2005) Invariant V14+ NKT cells participate in the early response to enteric Listeria monocytogenes infection. Journal of Immunology 175:1137-44.
  • Vosshenrich, C.A.J., Samson, S.I. and Di Santo, J.P. (2005) Distinguishing features of developing natural killer cells. Current Opinion in Immunology 17:151-8.
  • Delgado, J.-P., Parouchev, A., Allain, J.-E., Pennarun, G.,Gauthier, L.R., Dutrillaux, A.-M., Dutrillaux, B., Di Santo, J.P.,Capron, F., Boussin, F.D. and Weber, A. (2005) Long-term controlled immortalization of a primate hepatic progenitor cell line after Simian Virus 40 T- Antigen gene transfer. Oncogene 24:541-551.
  • Vosshenrich, C.A.J., Ranson, T., Samson, S.I., Colucci, F., Rosmaraki, E .E. and Di Santo, J.P. (2005) Roles for c-dependent cytokines in the generation, differentiation and maturation of NK cell precursors and peripheral NK cells in vivo. Journal of Immunology  174:1213-1221.