Centre d'Immunologie Humaine

Projets actuellement menés au sein du CIH :

1. HCV Immunology Principal investigator: M. ALBERT, MD PhD (Institut Pasteur). 2. Immune responses in the bladder Principal investigator: M. Ingersoll PhD (Institut Pasteur). 3. Defining the influence of HCV on the T cell pre-immune repertoire Principal investigator: C . Alanio (Institut Pasteur). 4. Manipulation of cell death pathways by viruses and microbes Principal investigators: Nader Yatim (Institut Pasteur). 5. Humanized mice for biomedical research Principal investigator: J. DI SANTO, MD PhD (Institut Pasteur). 6. Linking genotype, cell function and pathology in inflammatory disease Principal investigator: L. ROGGE, PhD (Institut Pasteur). 7. Epigenetic regulation of CD4+ T cell differentiation Principal investigator: E. Bianchi (Institut Pasteur). 8. Diversity of mouse NKp46+ cells Principal investigator: C. Vosshenrich (Institut Pasteur). 9. DNA damage in HIV-infected cells Principal investigator: J. DI SANTO, MD PhD (Institut Pasteur). 10. Role of the innate immunity in the induction of anti-HIV1 protective responses Principal investigator: F.Barre-Sinoussi MD PhD (Institut Pasteur). 11. The HTLV-1 cell to cell transmission Principal investigator: A. Alcover (Institut Pasteur). 12. Cellular orchestration of the T cell and NK cell responses during infection with Leichmania major Principal investigator: P. Bousso , PhD (Institut Pasteur). 13. Role of the stroma in the regulation of hematopoiesis, application to the myeloproliferative syndrome Principal investigator: R. Golub, PhD (Institut Pasteur).

14. Study of neonatal DC responses

Principal investigator: R. Lo-Man, PhD (Institut Pasteur).

15. Identification of prognitors to innate lymphoid cells and lymphoid stromal cells
Principal investigator: G. Eberl, PhD (Institut Pasteur).

16. Correlation of the intracellular localization of invasive pathogens with the induced host responses
Principal investigator: J. Enninga, PhD (Institut Pasteur).

17. Etude de l'entrée des menozoites de plasmodium berghei dans les erythrocytes de rongeur par imagerie en flux
Principal investigator: A. Freitas, PhD (Institut Pasteur).

18. study of the heterogeneity of healthy plasma cell population
Principal investigator: F. Huetz, PhD (Institut Pasteur).

19. Humanized mice for immune development and disease
Principal investigator: G. Azar, PhD (Institut Pasteur).

20. Etude de l'entrée des menozoites de plasmodium berghei dans les erythrocytes de rongeur par imagerie en flux
Principal investigator: D. Youssuf-Bargieri, PhD (Institut Pasteur).

21. APOBEX 3 enzymes and apoptosis
Principal investigator: S. Wain-Hobson, PhD (Institut Pasteur).

22. X-inactivation in differentiated ES cells

Principal investigator: P. Clerc, PhD (Institut Pasteur).

23. Study of imprinted x-inactivation during early mouse embryogenesis
Principal investigator: C, Morey, PhD (Institut Pasteur).

24. Manipulation of the adoptive immune response by Shigella
Principal investigator: A. Phalipon, PhD (Institut Pasteur).

25. Study of the heterogeneity of marginal zone B cell population in human
Principal investigator: D. Bagnara, PhD (Necker).

26. Kinetics of gene exression in cells infected in vitro with Yersinia pestis or the Raft Valley fever virus
Principal investigator: Jean-Jacques Panthier, PhD (Institut Pasteur).

27. Deciphering dormancy of Cryptococcus neoformans in vivo and in vitro
Principal investigator: A. Alanio, PhD (Institut Pasteur).

28. Multiplex analysis of Ab as biomarkers for malaria
Principal investigator: R. Perraut, PhD (Institut Pasteur).

29. Biological validation of anti-malaria frug candidates targeting host cell invasion
Principal investigator: C. Barrale, PhD (Institut Pasteur).

30. Surface antigens of P. falciparum parasites
Principal investigator: I. Vigan-Womas PhD (Institut Pasteur).

31. Analysis of artesunate-incuded dormancy in P. falciaprum parasites
Principal investigator: C. Barrale PhD (Institut Pasteur).

32. Characterization of histone modifications during infection with Listeria monocytogenes
Principal investigator: M. Hamon, PhD (Institut Pasteur).

33. HeLa cells infected with Listeria monocytogenes
Principal investigator: J. Pizarro-Cerda, PhD (Institut Pasteur).

34. Epigenetic reprogramming by the bacterial pathogen listeria monodytogenes
Principal investigator: A. Paliwai, PhD (Institut Pasteur).

35. Clonotypic characterization of HIV-specific CD4+ T cells from HIV controllers
Principal investigator: L. Chakrabarti PhD (Institut Pasteur).

36. Immunomodulatory activity of type I IFN on human blood cells
Principal investigator: M. Frederique, PhD (Institut Pasteur).