Publications clés



Lasserre R., Cuche C., Blecher-Gonen R., Libman E, Biquand E., Danckaert A., Yablonski D., Alcover A., and Di Bartolo V. Release of serine/threonine-phosphorylated adaptors from signaling microclusters downregulates T cell activation. J. Cell Biol. 2011. 195: 839-853. PMID: 22105350

Thoulouze M.I., Alcover A. Can viruses form biofilms ? Trends Microbiol. 2011. 19:257-62. (Review). PMID : 21458997
 
Alcover A., Thoulouze M. I. Transmission intercellulaire des rétrovirus : de nouvelles structures infectieuses, potentielles cibles thérapeutiques. Biofutur 2010. 29/315 : 48-53. (Revue en français). 
 
Thoulouze M. I., Alcover A. Le « biofilm viral »: un nouveau mode de dissémination des virus? Med. Sci. 2010. 26: 571-573. (Revue en français). PMID : 20619153
 
Lasserre R., Alcover A. Cytoskeletal cross-talk in the control of T cell antigen receptor signaling. FEBS Lett. 2010b 584 : 4845-4850. (Review). PMID : 20828561
 
Lasserre, R., Charrin, S., Cuche, C., Danckaert, A., Thoulouze, M. I., de Chaumont, F., Duong, T., Perrault, N., Varin-Blank, N., Olivo-Marin, J. C., Etienne-Manneville, S., Arpin, M., Di Bartolo, V., Alcover, A. Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse. EMBO J. 2010a. 29 : 2301-2314. PMID : 20551903
 
Pais-Correia A. M., Sachse M., Guadagnini S., Robbiati V., Lasserre R., Gessain A., Gout O., Alcover A., Thoulouze M. I. Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses. Nature Med. 2010. 16: 83-9. PMID: 20023636. 

Alcover A., Thoulouze M. I. Vesicle traffic to the immunological synapse. A multifunctional process targeted by lymphotropic viruses. Curr. Topics Microbiol. Immunol. 2010. 340:191-207. (Review). PMID : 19960315.

Mugnier B., Nal B., Verthuy C., Boyer C., Lam D., Chasson L., Nieoullon V., Chazal G., Guo X. J., He H. T., Rueff-Juy D., Alcover A., Ferrier P. Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling. PLoS ONE. 2008. 3:e3467. PMID: 18941544. 
Acuto O., Di Bartolo V., Michel F. Tailoring T-cell receptor signals by proximal negative feedback mechanisms. Nat. Rev. Immunol. 2008. 8:699-712. (Review). PMID: 18728635. 

Schwartz O., Alcover A., Fackler O. T. Modulation of the immunological synapse : a key to HIV-1 pathogenesis ? Nat. Rev. Immunol. 2007. 7 : 310-317. (Review). PMID: 17380160.
 
Di Bartolo V., Montagne B., Salek M., Jungwirth B., Carrette F., Fourtane J., Sol-Foulon N., Michel F., Schwartz O., Lehmann W. D., and Acuto O. A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76. J. Exp. Med. 2007. 204:681-691. PMID: 17353368. 
 
Pais-Correia A. M., Thoulouze M. I., Alcover A. T cell polarization and the formation of the immunological synapse : from antigen recognition to virus spread. Curr. Immunol. Rev. 2007. 3 : 107-188. (Review). http://hal-pasteur.archives-ouvertes.fr/pasteur-00350265/fr/

Sol-Foulon N., Sourisseau, M., Porrot, F., Thoulouze, M. I., Trouillet, C., Nobile, C., Blanchet, F., Di Bartolo, V., Noraz, N., Taylor, N., Alcover, A., Hivroz, C., Schwartz, O. ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation. EMBO J. 2007. 26 : 512-526. PMID: 17215865 

Thoulouze M. I., Sol-Foulon N., Blanchet F., Dautry-Varsat A., Schwartz O., Alcover A. Human immunodeficiency virus (HIV-1) impairs the formation of the immunological synapse. Immunity. 2006 24 :547-561. PMID: 16713973 

Charrin S., Alcover A. Role of ERM (ezrin-radixin-moesin) proteins in T lymphocyte polarization, Immune synapse Formation and in T cell receptor-mediated signaling. Front. Biosci. 2006. 11 : 1987-1997. (Review). PMID: 16368573. 

Alcover A., Thoulouze M. I. Galli T. Recyclage polarisé et formation de la synapse immune dans les lymphocytes T. Med. Sci. 2005. 21 : 9-10. (Review, french). PMID: 15639007. 

Das V., Nal B., Dujeancourt A., Thoulouze M. I., Galli T., Roux P., Dautry-Varsat A., Alcover A. Activation-induced polarized recycling targets T cell receptors to the immunological synapse. Involvement of SNARE complexes. Immunity. 2004, 20: 577-588. PMID: 15142526. 

Nal B., Carroll P., Mohr E., Verthuy C., Da Silva M. I., Gayet O., Guo X. J., He H. T., Alcover A., Ferrier P. Coronin-1 expression in T lymphocytes : Insights into protein function during T cell development and activation. Int. Immunol. 2004. 16 : 231-240. PMID: 14734608. 

Das V., Nal B., Roumier A., Meas-Yedid V., Zimmer C., Olivo-Marin J.C., Roux P., Ferrier P., Dautry-Varsat A., Alcover A. Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T cell activation. Immunol. Rev. 2002 189 : 123-135. (Review). PMID: 12445270. 

Roumier A., Olivo-Marin J.C., Arpin M., Michel F., Martin M., Mangeat P., Acuto O., Dautry-Varsat A., Alcover A. The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation. Immunity. 2001. 15: 715-728. PMID: 11728334.