Publications

2013

Mosci, P., Pericolini, E., Gabrielli, E., Kenno, S., Perito, S., Bistoni, F., d'Enfert, C., and Vecchiarelli, A. (2013) A novel bioluminescence mouse model for monitoring oropharyngeal candidiasis in mice. Virulence 4: 250-254

Zeidler, U., Bougnoux, M.E., Lupan, A., Helynck, O., Doyen, A., Garcia, Z., Sertour, N., Clavaud, C., Munier-Lehman, H., Saveanu, C. and d’Enfert C. (2013) Synergy of the antibiotic colistin with echinocandin antifungals in Candida species. J Antimic Chemother. 68: 1285-1296

Gastebois, A., Amainianda, V., Bachellier-Bassi, S., Nesseir, A., Firon, A., Beauvais, A., Schmitt, C., England, P., Beau, R., Prévost, M.-C., d’Enfert, C., Latgé, J.-P. and Mouyna, I. (2013) SUN-proteins belong to a novel family of -(1,3)-glucan modifying enzymes involved in fungal morphogenesis. J Biol Chem. 288: 13387-13396

Rossignol, T., Kocsis, B., Bouquet, O., Kustos, I., Kilar, F., Nyul, A., Jakus, P.B., Kerekes, S., Rajbhandari, K., Prokai, L., d’Enfert, C. and Lorand, T. (2013) Antifungal activity of fused Mannich ketones triggers an oxidative stress response and is Cap1 dependant in Candida albicans. PLoS One 8: e62142

Bonhomme, J. and d’Enfert, C. (2013) Candida albicans biofilms : building a heterogeneous, drug-tolerant environment. Curr Op Microbiol 16 : 398-403

Angebault, C., Djossou, F., Abélanet, S., Permal, E., Ben Soltana, M., Diancourt, L., Bouchier, C., Woerther, P.-L., Catzeflis, F., Andremont, A., d’Enfert, C., and Bougnoux, M.E. (2013) Candida albicans is not always the preferential yeast colonising humans: a study amongst Wayampi Amerindians. J Infect Dis 208: 1705-1716

Znaidi, S., Nesseir, A., Chauvel, M., Rossignol, T. and d’Enfert, C. (2013) A Comprehensive functional portrait of two Heat Shock Factor-type transcriptional regulators involved in Candida albicans morphogenesis and virulence. PLoS Pathogens 9: e1003519

Vediyappan, G., Dumontet, V., Pelissier, F. and d'Enfert, C. (2013) Gymnemic acids inhibit hyphal growth and virulence in Candida albicans. PLoS One 8: e74189

Monniot, C., Boisramé, A., Da Costa, G., Chauvel, M., Sautour, M., Bougnoux, M.E., Bellon-Fontaine, M.N., Dalle, F., d’Enfert, C. and Richard, M. (2013) Rbt1 protein domains analysis in Candida albicans brings insights into hyphal surface modifications and Rbt1 potential role during adhesion and biofilm formation. PLoS One, in press.

2012

Gutierrez-Escribano P, Zeidler U, Suarez MB, Bachellier-Bassi S, Clemente-Blanco A, Bonhomme J, Vazquez de Aldana CR, d'Enfert C, Correa-Bordes J (2012) The NDR/LATS Kinase Cbk1 Controls the Activity of the Transcriptional Regulator Bcr1 during Biofilm Formation in Candida albicans. PLoS Pathog 8: e1002683

Cabral V, Chauvel M, Firon A, Legrand M, Nesseir A, Bachellier-Bassi S, Chaudhari Y, Munro CA, d'Enfert C (2012) Modular Gene Over-expression Strategies for Candida albicans. Methods Mol Biol 845: 227-244

Riera M, Moreno-Ruiz E, Goyard S, d'Enfert C, Janbon G (2012) Biofilm formation studies in microtiter plate format. Methods Mol Biol 845: 369-377

Pietrella D, Enjalbert B, Zeidler U, Znaidi S, Rachini A, Vecchiarelli A, d'Enfert C (2012) A Luciferase Reporter for Gene Expression Studies and Dynamic Imaging of Superficial Candida albicans Infections. Methods Mol Biol 845: 537-546

Vecchiarelli A, d'Enfert C (2012) Shedding natural light on fungal infections. Virulence 3: 15-17

Riera M, Mogensen E, d'Enfert C, Janbon G (2012) New regulators of biofilm development in Candida glabrata. Res Microbiol., 163: 297-307

L'Ollivier, C., Labruere, C., Jebrane, A., Bougnoux, M. E., d'Enfert, C., Bonnin, A. and Dalle, F. (2012) Using a Multi-Locus Microsatellite Typing method improved phylogenetic distribution of Candida albicans isolates but failed to demonstrate association of some genotype with the commensal or clinical origin of the isolates. Infect Genet Evol 12: 1949-1957

Chauvel, M., Nesseir, A., Cabral, V., Znaidi, S., Goyard, S., Bachellier-Bassi, S., Firon, A., Legrand, M., Diogo, D., Naulleau, C., Rossignol, T., and d'Enfert, C. (2012) A versatile overexpression strategy in the pathogenic yeast Candida albicans: Identification of regulators of morphogenesis and fitness. PLoS One 7: e45912

2011

Dai, T., Kharkwal, GB., Zhao, J., Denis, TG., Wu, Q., Xia, Y., Huang, L., Sharma, SK., d'Enfert, C., Hamblin, MR (2011) Ultraviolet-C Light for Treatment of Candida albicans Burn Infection in Mice. Photochem Photobiol 87 : 342-349

Bonhomme, J., Chauvel, M., Goyard, S., Roux, P., Rossignol, T., d'Enfert, C (2011) Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans. Mol Microbiol 80 : 995-1013

Shin, JH., Bougnoux, ME., d'Enfert, C., Kim, SH., Moon, CJ., Joo, MY., Lee, K., Kim, MN., Lee, HS., Shin, MG., Suh, SP., Ryang, DW (2011) Genetic Diversity among Korean Candida albicans Bloodstream Isolates: Assessment by Mutilocus Sequence Typing and Restriction Endonuclease Analysis of Genomic DNA using BssHII. J Clin Microbiol 49 : 2572-2577

Rossignol T, Kelly B, Dobson C, d'Enfert C (2011) Endocytosis-mediated vacuolar accumulation of the human ApoE apolipoprotein-derived ApoEdpL-W antimicrobial peptide contributes to its antifungal activity in Candida albicans. Antimicrob Agents Chemother 55: 4670-4681

Pietrella D, Rachini A, Pines M, Pandey N, Mosci P, Bistoni F, d'Enfert C, Vecchiarelli A (2011) Th17 cells and IL-17 in protective immunity to vaginal candidiasis. PLoS One 6: e22770

Legrand M, Munro CA, d'Enfert C (2011) Cool Tools 5: The Candida albicans ORFeome project. In Candida and candidiasis, 2nd edition, Calderone RA, Clancy CJ (eds), pp 505-510. Washington DC: ASM Press

2010

Spiering, M. J., G. P. Moran, M. Chauvel, D. M., Maccallum, J. Higgins, K. Hokamp, T. Yeomans, C. d’Enfert, D.C. Coleman, and D. J. Sullivan (2010) Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model, Eukaryot Cell 9: 251-265 (PMC2823005)

Vediyappan, G., T. Rossignol, and C. d’Enfert (2010) Interaction of Candida albicans biofilms with antifungals: transcriptional response and binding of antifungals to beta-glucans, Antimicrob Agents Chemother 54: 2096-2111

Spiering MJ, Moran GP, Chauvel M, Maccallum DM, Higgins J, Hokamp K, Yeomans T, d'Enfert C, Coleman DC, Sullivan DJ (2010) Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model. Eukaryot Cell 9: 251-265

Pietrella D, Rachini A, Torosantucci A, Chiani P, Brown AJ, Bistoni F, Costantino P, Mosci P, d'Enfert C, Rappuoli R, Cassone A, Vecchiarelli A (2010) A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique. Vaccine 28: 1717-1725

Jacobsen ID, Brunke S, Seider K, Schwarzmuller T, Firon A, d'Enfert C, Kuchler K, Hube B (2010) Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy. Infect Immun 78: 1066-1077

Carr PD, Tuckwell D, Hey PM, Simon L, d'Enfert C, Birch M, Oliver JD, Bromley MJ (2010) The transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus. Eukaryot Cell 9: 438-448

2009

Rossignol, T., C. Ding, A. Guida, C. d’Enfert, D. G. Higgins, and G. Butler. (2009). Correlation between biofilm formation and the hypoxic response in Candida parapsilosis. Eukaryot Cell 8:550-559. (PMC2669199)

Moreno-Ruiz, E., M. Galan-Diez, W. Zhu, E. Fernandez-Ruiz, C. d’Enfert, S. G. Filler, P. Cossart, and E. Veiga. (2009). Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism. Cell Microbiol 11:1179-1189

Enjalbert, B., A. Rachini, G. Vediyappan, D. Pietrella, R. Spaccapelo, A. Vecchiarelli, A. J. Brown, and C. d’Enfert. (2009). A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections. Infect Immun 77:4847-4858. (PMC2772526)

Diogo, D., Bouchier, C., d’Enfert, C. and Bougnoux, M.E. (2009). Loss of heterozygosity in commensal isolates of the asexual diploid yeast Candida albicans. Fungal Genet Biol 46: 159-168

Moreno-Ruiz, E., Ortu, G., de Groot, P.W., Cottier, F., Loussert, C., Prevost, M.C., de Koster, C., Klis, F.M., Goyard, S. and d’Enfert, C. (2009). The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity. Microbiology 155: 2004-2020

McManus, B.A., Sullivan, D.J., Moran, G.P., d’Enfert, C., Bougnoux, M.-E., Nunn, M.A., and Coleman, D.C. (2009) Avian- and human-isolates of Candida dubliniensis are genetically distinct. Emerg. Infect. Dis., 15:1467-1470

d’Enfert, C. (2009) Hidden killers: Persistence of opportunistic fungal pathogens in the human host. Curr. Op. Microbiol.12:358-364

2008

Jacobsen, M.D., Bougnoux, M.E., d’Enfert, C. and Odds, F.C. (2008). Multilocus sequence typing of Candida albicans isolates from animals. Res Microbiol 159: 436-440

Rossignol, T., Lechat, P., Cuomo, C., Zeng, Q., Moszer, I., and d’Enfert, C. (2008). CandidaDB: a multi-genome database for Candida species and related Saccharomycotina. Nucleic Acids Res 36: D557-561. (PMC2238939)

Goyard, S., Knechtle, P., Chauvel, M., Mallet, A., Prevost, M.C., Proux, C., Coppee, J.Y., Schwartz, P., Dromer, F., Park, H., Filler, S.G., Janbon, G., and d’Enfert, C. (2008). The Yak1 Kinase Is Involved in the Initiation and Maintenance of Hyphal Growth in Candida albicans. Mol Biol Cell 19: 2251-2266. (PMC2366847)

McManus, B.A., Coleman, D.C., Moran, G., Pinjon, E., Diogo, D., Bougnoux, M.E., Borecka-Melkusova, S., Bujdakova, H., Murphy, P., d’Enfert, C., and Sullivan, D.J. (2008). Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans. J Clin Microbiol 46: 652-664

Bougnoux, M.E., Pujol, C., Diogo, D., Bouchier, C., Soll, D.R., and d’Enfert, C. (2008). Mating is rare within as well as between clades of the human pathogen Candida albicans. Fungal Genet Biol 45: 221-231

Bougnoux, M.E., Kac, G., Aegerter, P., d’Enfert, C., and Fagon, J.Y. (2008). Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome. Intensive Care Med 34: 292-299

McManus, B.A., Coleman, D.C., Moran, G., Pinjon, E., Diogo, D., Bougnoux, M.E., Borecka-Melkusova, S., Bujdakova, H., Murphy, P., d’Enfert, C. and Sullivan, D.J. (2008) Multilocus Sequence Typing Reveals that the Population Structure of Candida dubliniensis is Significantly Less Divergent than that of Candida albicans. J Clin Microbiol 46: 652-664 [Abstract]

Rossignol, T., Lechat, P., Cuomo, C., Zeng, Q., Moszer, I. and d’Enfert, C. (2008) CandidaDB: a multi-genome database for Candida species and related Saccharomycotina. Nucleic Acids Res 36: D557-561 [Abstract]

2007

Bougnoux, M.E., Diogo, D., Pujol, C., Soll, D.R. and d’Enfert, C. (2007) Molecular epidemiology and population dynamics in Candida albicans. In d’Enfert, C. and Hube, B. (eds.), Candida: comparative and fucntional genomics. Caister Academic Press, Wymondham, United Kingdom, pp. 51-70

Bougnoux, M.E., Pujol, C., Diogo, D., Bouchier, C., Soll, D.R. and d’Enfert, C. (2007) Mating is rare within as well as between clades of the human pathogen Candida albicans. Fungal Genet Biol., 45:221-231 [Abstract]
 
Coste, A., Selmecki, A., Forche, A., Diogo, D., Bougnoux, M.E., d’Enfert, C., Berman, J. and Sanglard, D. (2007) Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates. Eukaryot Cell, 6: 1889-1904 [Abstract]
 
d’Enfert, C. and Hube, B. (2007) Candida: comparative and fucntional genomics. Caister Academic Press, Wymondham, United Kingdom
 
Firon, A., Aubert, S., Iraqui, I., Guadagnini, S., Goyard, S., Prevost, M.C., Janbon, G. and d’Enfert, C. (2007) The SUN41 and SUN42 genes are essential for cell separation in Candida albicans. Mol Microbiol, 66: 1256-1275. [Abstract]
 
Firon, A. and d’Enfert, C. (2007) From genes to function: systematic approaches used to study Candida albicans and Candida glabrata biology and pathogenesis. In d’Enfert, C. and Hube, B. (eds.), Candida: comparative and fucntional genomics. Caister Academic Press, Wymondham, United Kingdom, pp. 195-216
 
Odds, F.C., Bougnoux, M.E., Shaw, D.J., Bain, J.M., Davidson, A.D., Diogo, D., Jacobsen, M.D., Lecomte, M., Li, S.Y., Tavanti, A., Maiden, M.C., Gow, N.A. and d’Enfert, C. (2007) Molecular phylogenetics of Candida albicans. Eukaryot Cell, 6: 1041-1052 [Abstract]

Pel, H.J., de Winde, J.H., Archer, D.B., Dyer, P.S., Hofmann, G., et al. (2007) Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Nat Biotechnol, 25: 221-231 [Abstract]

Yu, J. H. and d’Enfert, C.
(2007) Signal transduction in Aspergilli. In S. A. Osmani and G. H. Goldman (eds.), The Aspergilli: Genomics, Medical Applications, Biotechnology, and Research Methods. CRC Press

2006

Bougnoux, M.E., Diogo, D., Francois, N., Sendid, B., Veirmeire, S., Colombel, J.F., Bouchier, C., Van Kruiningen, H., d’Enfert, C. and Poulain, D. (2006) Multilocus sequence typing reveals intrafamilial transmission and microevolutions of Candida albicans isolates from the human digestive tract. J Clin Microbiol, 44: 1810-1820.[Abstract]

d’Enfert, C. (2006) Biofilms and their role in the resistance of pathogenic Candida to antifungal agents. Curr Drug Targets, 7: 465-470.[Abstract]

Lafon, A., Han, K.H., Seo, J.A., Yu, J.H. and d’Enfert, C. (2006) G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective. Fungal Genet Biol, 43: 490-502.[Abstract]

Peltroche-Llacsahuanga, H., Goyard, S., d’Enfert, C., Prill, S.K. and Ernst, J.F. (2006) Protein O-mannosyltransferase isoforms regulate biofilm formation in Candida albicans. Antimicrob Agents Chemother, 50: 3488-3491.[Abstract]

2005

Braun, B.R., van Het Hoog, M., d’Enfert, C., Martchenko, M., Dungan, J., et al. (2005) A human-curated annotation of the Candida albicans genome. PLoS Genet, 1: 36-57.[Abstract]
 
d’Enfert, C., Goyard, S., Rodriguez-Arnaveilhe, S., Frangeul, L., Jones, L., et al. (2005) CandidaDB: a genome database for Candida albicans pathogenomics. Nucleic Acids Res, 33: D353-357.[Abstract]

Galagan, J.E., Calvo, S.E., Cuomo, C., Ma, L.J., Wortman, J.R., et al. (2005) Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature, 438: 1105-1115.[Abstract]

Knechtle, P., Goyard, S., Brachat, S., Ibrahim-Granet, O. and d’Enfert, C. (2005) Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction. Res Microbiol, 156: 822-829.[Abstract]

Iraqui, I., Garcia-Sanchez, S., Aubert, S., Dromer, F., Ghigo, J.M., d’Enfert, C. and Janbon, G. (2005) The Yak1p kinase controls expression of adhesins and biofilm formation in Candida glabrata in a Sir4p-dependent pathway. Mol Microbiol, 55: 1259-1271.[Abstract]

Lafon, A., Seo, J.A., Han, K.H., Yu, J.H. and d’Enfert, C. (2005) The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans. Genetics, 171: 71-80. [Abstract]

2004

Bougnoux, M.E., Aanensen, D.M., Morand, S., Theraud, M., Spratt, B.G. and d’Enfert, C. (2004) Multilocus sequence typing of Candida albicans: strategies, data exchange and applications. Infect Genet Evol, 4: 243-252 [Abstract]

Garcia-Sanchez, S., Aubert, S., Iraqui, I., Janbon, G., Ghigo, J.M. and d’Enfert, C. (2004) Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns. Eukaryot Cell, 3: 536-545 [Abstract]

2003

Bougnoux, M.E., Tavanti, A., Bouchier, C., Gow, N.A., Magnier, A., Davidson, A.D., Maiden, M.C., D’Enfert, C. and Odds, F.C. (2003) Collaborative consensus for optimized multilocus sequence typing of Candida albicans. J Clin Microbiol, 41: 5265-5266 [Abstract]

de Vries, R.P., Flitter, S.J., van de Vondervoort, P.J., Chaveroche, M.K., Fontaine, T., Fillinger, S., Ruijter, G.J., d’Enfert, C. and Visser, J. (2003) Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans. Mol Microbiol, 49: 131-141 [Abstract]

Firon, A., Villalba, F., Beffa, R. and D’Enfert, C. (2003) Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis. Eukaryot Cell, 2: 247-255 [Abstract]

Fradin, C., Kretschmar, M., Nichterlein, T., Gaillardin, C., d’Enfert, C. and Hube, B. (2003) Stage-specific gene expression of Candida albicans in human blood. Mol Microbiol, 47: 1523-1543 [Abstract]

2002

Bougnoux, M.E., Morand, S. and d’Enfert, C. (2002) Usefulness of multilocus sequence typing for characterization of clinical isolates of Candida albicans. J Clin Microbiol, 40: 1290-1297 [Abstract]

Fillinger, S., Chaveroche, M.K., Shimizu, K., Keller, N. and d’Enfert, C. (2002) cAMP and ras signalling independently control spore germination in the filamentous fungus Aspergillus nidulans. Mol Microbiol, 44: 1001-1016 [Abstract]

Firon, A., Beauvais, A., Latge, J.P., Couve, E., Grosjean-Cournoyer, M.C. and D’Enfert, C. (2002) Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA. Genetics, 161: 1077-1087 [Abstract]

Firon, A. and d’Enfert, C. (2002) Identifying essential genes in fungal pathogens of humans. Trends Microbiol, 10: 456-462 [Abstract]

2001

Fillinger, S., Chaveroche, M.K., van Dijck, P., de Vries, R., Ruijter, G., Thevelein, J. and d’Enfert, C. (2001) Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans. Microbiology, 147: 1851-1862 [Abstract]

Fillinger, S., Ruijter, G., Tamas, M.J., Visser, J., Thevelein, J.M. and d’Enfert, C. (2001) Molecular and physiological characterization of the NAD-dependent glycerol 3-phosphate dehydrogenase in the filamentous fungus Aspergillus nidulans. Mol Microbiol, 39: 145-157 [Abstract]

Murad, A.M., d’Enfert, C., Gaillardin, C., Tournu, H., Tekaia, F., Talibi, D., Marechal, D., Marchais, V., Cottin, J. and Brown, A.J. (2001) Transcript profiling in Candida albicans reveals new cellular functions for the transcriptional repressors CaTup1, CaMig1 and CaNrg1. Mol Microbiol, 42: 981-994 [Abstract]

Murad, A.M., Leng, P., Straffon, M., Wishart, J., Macaskill, S., MacCallum, D., Schnell, N., Talibi, D., Marechal, D., Tekaia, F., d’Enfert, C., Gaillardin, C., Odds, F.C. and Brown, A.J. (2001) NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans. Embo J, 20: 4742-4752 [Abstract]