Curriculum vitae Marie-Anne Nahori
Citizenship: French
Professional address :
INSTITUT PASTEUR
Bacteria-cell interactions Unit – INSERM U604 – INRA USC2020
Department of Cell biology and Infection
25 rue du Docteur Roux -75724 PARIS Cedex 15-France.
E-mail: manaho@pasteur.fr
Present position and status: Staff scientist, Engineer
UNIVERSITARY EDUCATION
1986 Certificate of Statistics Applied to Clinical Studies (CESAM), University Paris VI, France.
1985 Master in Cellular and Molecular Pharmacology (DEA), University Paris VI, France.
RESEARCH EXPERIENCE
2005 Research Engineer, Unité des Interactions Bactéries-Cellules, Institut Pasteur, Paris, France. "Analysis of Listeria monocytogenes infection process in vivo and in vitro".
2002-2004 Research Engineer, Unité Cytokines et Inflammation (PTR 94), Institut Pasteur, Paris, France. Toll-like receptors and Nod proteins in innate immunity.
1986-2002 Research Engineer, Unité de Pharmacologie Cellulaire, Institut Pasteur, Paris, France. Bronchopulmonary pharmacology in mice and modulation of inflammatory response.
1984-1986 Research Engineer, Unité des Venins, Institut Pasteur, Paris. Development of polyvalent antisnake venom serum (Middle East and North Africa).
OTHER
2003 Certificate for animal experimentation (Level 2), Gif sur Yvette, France.
SELECTED PUBLICATION LIST
1. Nahori, MA, Fournie-Amazouz, E, Que-Gewirth, NS, Balloy, V, Chignard, M, Raetz, CR, Saint-Girons, I, and Werts. C. 2005. Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells. J. Immunol. 175, 6022-6031.
2. Balloy, V, Si-Tahar, M, Takeuchi, O, Philippe, B, Nahori, MA, Tanguy, M, Huerre, M, Akira, S, Latge, JP, and Chignard M.. 2005. Involvement of Toll-like receptor 2 in experimental invasive pulmonary aspergillosis. Infect. Immun. 73, 5420-5425.
3. Magalhaes, JG, Philpott, DJ, Nahori, MA, Jehanno, M, Fritz, J, Bourhis, LL, Viala, J, Hugot, JP, Giovannini, M, Bertin, J, Lepoivre, M, Mengin-Lecreulx, D, Sansonetti, PJ, and Girardin, SE. 2005. Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin. EMBO Rep. 12, 1201-1207.
4. Travassos, LH, Girardin, SE, Philpott, DJ, Blanot, D, Nahori, MA, Werts, C, and Boneca, IG. 2004. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep. 5, 1000-1006.
5. Nahori, MA, Lagranderie, M, Lefort, J, Thouron, F, Joseph, D, Winter, N, Giquel, B, Lapa e Silva, JR, and Vargaftig, BB. 2001. Effects of Mycobacterium bovis BCG on the development of allergic inflammation and bronchial hyperrresponsiveness in hyper-IgE BP2 mice vaccinated as newborns. Vaccine. 19, 1484-1495.
6. Russo, M, Nahori, MA, Lefort, J, Gomes, E, de Castro Keller, A, Rodriguez, D, Garcia Ribeiro, O, Adriouch, S, Gallois V, and Vargaftig, BB. 2001. Suppression of asthma like responses in different mouse strains by oral tolerance. Am. J. Respir. Cell Mol. Biol. 24, 518-526.
7. Lefort, J, Nahori, MA, Ruffié, C, Vargaftig, BB, and Pretolani, M. 1996. In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperreactivity in sensitized guinea-pigs. J. Clin. Invest. 97, 1117-1121.
8. Nahori, MA, Etievant, M, Terzidis-Trabelsi, H, David, B, and Lambré, C. 1994. Binding of serum autoantibodies to sialidase-treated tracheal epithelial cells. Determination of autoantibodies isotypes in normal and influenza virus infected guinea pig sera. Immunol. Lett. 42, 67-73.
9. Nahori, MA, Renesto, P, Vargaftig, BB, and Chignard, M. 1992. Activation and damage of cultured airway epithelial cells by human elastase and cathepsin G. Eur. J. Pharmacol. 228, 213-218.
10. Nahori, MA, Prévost, MC, and Gounon, P. 1991. Guinea pig tracheal epithelial cells in primary culture: morphological and metabolic characterization. J. Lipid Med. 3, 101-112.
PATENT
2002 Nahori, MA, Lagranderie, M, Marchal, Vargaftig, BB, Lefort, J, Romain, F, Hekimian, G, Peltre, P. G"Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation". Patent # 02804652.22107-IB0205760