Recherche / Départements scientifiques / Biologie cellulaire et infection / Unités et groupes / Unité des Interactions Bactéries-Cellules / Team
Curriculum vitae Cristel Archambaud
Cristel Archambaud
Professional address:
Laboratory of Prof. P. Cossart
Bacteria-Cell Interaction Unit – INSERM U604 – INRA USC2020
Department of Cell Biology and Infection
Institut Pasteur
25 Rue du Dr Roux
75015 Paris Cedex 15
France
Email: cristel.archambaud@pasteur.fr
Phone: +33-1-406137799
Present position: Post-doctoral fellow
Education:
2008 Diploma of Animal Experimentation, level I, Marseille, France
2006 PhD in Microbiology, Paris VII, France
2004 Diploma of Molecular Biology of the Cell, Curie & Pasteur Institutes, Paris, France
2002 Master of Fundamental Microbiology (DEA), Paris VII, France
2002 Diploma of General Microbiology, Pasteur Institute, Paris, France
2000-2001 License & Master’s Degree in Biochemistry, Paris VI, France
Research Experience:
2009- Post-doctoral fellow supervised by Pr. P. Cossart in the unit of “Bacteria Cell Interactions”, Pasteur Institute, Paris, France
Subject: Effect of commensals and probiotics on the enteropathogenicity of the model microorganism Listeria monocytogenes
2006-2008 Post-doctoral fellow supervised by Pr Bernard Malissen in the laboratory of “Genetic and structural analysis of T cell interactions”, Centre d’Immunologie de Marseille-Luminy, Marseille, France
Subject 1: Role of dendritic cells in Brucella infection in vivo
Subject 2: Molecular and cellular pathways involved in the lymphoproliferative disorder occuring in mice with point mutation in the gene coding for the LAT adaptor
2002-2006 Ph.D. thesis supervised by Pr. P. Cossart and Dr. O. Dussurget in the unit of “Bacteria Cell Interactions”, Pasteur Institute, Paris, France
Subject: Role of the serine-threonine phosphatase Stp in the infectious process of L. monocytogenes
2002 DEA stage supervised by Pr. P. Cossart and Dr. O. Dussurget in the unit of “Bacteria Cell Interactions”, Pasteur Institute, Paris, France
Subject: Characterization of the system of serine-threonine phosphatase/kinase in L. monocytogenes
2001 Stage supervised by Dr. L. Christa in the unit of “Hepatic carcinogenesis and molecular virology”, Necker Institute, Paris, France
Subject: Analysis of the role of the PKA in mitogenic and anti-apoptotic functions of the HIP/PAP protein in liver
Teaching Experience:
2004 General Microbiology practical laboratory course, Pasteur Institute, Paris, France
Prize
PathoGenoMics PhD Award 2007
Publications List
1. Cossart P and Archambaud C
The bacterial pathogen Listeria monocytogenes: an emerging model in prokaryotic transcriptomics. J. Biol. 8(12):107, 2009
2. Archambaud C, Sansoni A, Mingueneau M, Devilard E, Delsol G, Malissen B & Malissen M
STAT6 deletion converts the Th2 inflammatory pathology afflicting LatY136F mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells, J. Immunol., 182(5):2680-9, 2009
3. Mingueneau M, Roncagalli R, Grégoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, Richelme S, Locksley RM, Aguado E, Malissen M & Malissen B.
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity 31(2):197-208, 2009
4. Archambaud C, Nahori MA, Pizarro-Cerda J, Cossart P & Dussurget O
Control of Listeria superoxide dismutase by phosphorylation, J. Biol. Chem., 281(42):31812-22, 2006
5. Archambaud C, Gouin E, Pizarro-Cerda J, Cossart P & Dussurget O
Translation elongation factor EF-Tu is a target for Stp, a serine-threonine phosphatase involved in virulence of Listeria monocytogenes, Mol. Microbiol., 56(2): 383-96, 2005.
6. Dussurget O, Dumas E, Archambaud C, Chafsey I, Chambon C, Hébraud M & Cossart P
Listeria monocytogenes ferritin protects against multiple stresses and is required for virulence, FEMS Microbiol. Lett., 250(2): 253-61, 2005.
7. Sousa S, Cabanes D, Archambaud C, Colland F, Lemichez E, Popoff M, Dupuis S, Gouin E, Lecuit M, Legrain P & Cossart P
ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion, Nat. Cell Biol., 7(10): 954-60, 2005
Oral communications
Etude de la dynamique et de la fonction des DCs in vivo
Colloque sur la Recherche Biomédicale ANR et bilan des programmes 2005
November, 26-27, 2009, Paris, France
Role of the serine-threonine phosphatase Stp in the infectious process of Listeria monocytogenes
ProkaGENOMICS 2007
October 7-10, 2007, Göttingen, Germany
Role of STAT6 in the Th2- lymphoproliferative disease developing in mice with a point mutation in the LAT adaptor
2nd ENII-MUGEN Immunology Summer School
April 14-21, 2007, Capo Caccia, Sardinia, Italy
Translation elongation factor EF-Tu is a target for Stp, a novel serine-threonine phosphatase of Listeria monocytogenes
13th International Conference on Bacilli «Functional Genomics of Gram-positive Microorganisms»
June 12-16, 2005, San Diego, California, USA
Role of the serine-threonine phosphatase Stp in the infectious process of Listeria monocytogenes
Vème colloque «Phosphorylation des protéines» (Société Française de Biochimie et Biologie Moléculaire)
September 26-29, 2004, Presqu’île de Giens, France
Professional address:
Laboratory of Prof. P. Cossart
Bacteria-Cell Interaction Unit – INSERM U604 – INRA USC2020
Department of Cell Biology and Infection
Institut Pasteur
25 Rue du Dr Roux
75015 Paris Cedex 15
France
Email: cristel.archambaud@pasteur.fr
Phone: +33-1-406137799
Present position: Post-doctoral fellow
Education:
2008 Diploma of Animal Experimentation, level I, Marseille, France
2006 PhD in Microbiology, Paris VII, France
2004 Diploma of Molecular Biology of the Cell, Curie & Pasteur Institutes, Paris, France
2002 Master of Fundamental Microbiology (DEA), Paris VII, France
2002 Diploma of General Microbiology, Pasteur Institute, Paris, France
2000-2001 License & Master’s Degree in Biochemistry, Paris VI, France
Research Experience:
2009- Post-doctoral fellow supervised by Pr. P. Cossart in the unit of “Bacteria Cell Interactions”, Pasteur Institute, Paris, France
Subject: Effect of commensals and probiotics on the enteropathogenicity of the model microorganism Listeria monocytogenes
2006-2008 Post-doctoral fellow supervised by Pr Bernard Malissen in the laboratory of “Genetic and structural analysis of T cell interactions”, Centre d’Immunologie de Marseille-Luminy, Marseille, France
Subject 1: Role of dendritic cells in Brucella infection in vivo
Subject 2: Molecular and cellular pathways involved in the lymphoproliferative disorder occuring in mice with point mutation in the gene coding for the LAT adaptor
2002-2006 Ph.D. thesis supervised by Pr. P. Cossart and Dr. O. Dussurget in the unit of “Bacteria Cell Interactions”, Pasteur Institute, Paris, France
Subject: Role of the serine-threonine phosphatase Stp in the infectious process of L. monocytogenes
2002 DEA stage supervised by Pr. P. Cossart and Dr. O. Dussurget in the unit of “Bacteria Cell Interactions”, Pasteur Institute, Paris, France
Subject: Characterization of the system of serine-threonine phosphatase/kinase in L. monocytogenes
2001 Stage supervised by Dr. L. Christa in the unit of “Hepatic carcinogenesis and molecular virology”, Necker Institute, Paris, France
Subject: Analysis of the role of the PKA in mitogenic and anti-apoptotic functions of the HIP/PAP protein in liver
Teaching Experience:
2004 General Microbiology practical laboratory course, Pasteur Institute, Paris, France
Prize
PathoGenoMics PhD Award 2007
Publications List
1. Cossart P and Archambaud C
The bacterial pathogen Listeria monocytogenes: an emerging model in prokaryotic transcriptomics. J. Biol. 8(12):107, 2009
2. Archambaud C, Sansoni A, Mingueneau M, Devilard E, Delsol G, Malissen B & Malissen M
STAT6 deletion converts the Th2 inflammatory pathology afflicting LatY136F mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells, J. Immunol., 182(5):2680-9, 2009
3. Mingueneau M, Roncagalli R, Grégoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, Richelme S, Locksley RM, Aguado E, Malissen M & Malissen B.
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity 31(2):197-208, 2009
4. Archambaud C, Nahori MA, Pizarro-Cerda J, Cossart P & Dussurget O
Control of Listeria superoxide dismutase by phosphorylation, J. Biol. Chem., 281(42):31812-22, 2006
5. Archambaud C, Gouin E, Pizarro-Cerda J, Cossart P & Dussurget O
Translation elongation factor EF-Tu is a target for Stp, a serine-threonine phosphatase involved in virulence of Listeria monocytogenes, Mol. Microbiol., 56(2): 383-96, 2005.
6. Dussurget O, Dumas E, Archambaud C, Chafsey I, Chambon C, Hébraud M & Cossart P
Listeria monocytogenes ferritin protects against multiple stresses and is required for virulence, FEMS Microbiol. Lett., 250(2): 253-61, 2005.
7. Sousa S, Cabanes D, Archambaud C, Colland F, Lemichez E, Popoff M, Dupuis S, Gouin E, Lecuit M, Legrain P & Cossart P
ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion, Nat. Cell Biol., 7(10): 954-60, 2005
Oral communications
Etude de la dynamique et de la fonction des DCs in vivo
Colloque sur la Recherche Biomédicale ANR et bilan des programmes 2005
November, 26-27, 2009, Paris, France
Role of the serine-threonine phosphatase Stp in the infectious process of Listeria monocytogenes
ProkaGENOMICS 2007
October 7-10, 2007, Göttingen, Germany
Role of STAT6 in the Th2- lymphoproliferative disease developing in mice with a point mutation in the LAT adaptor
2nd ENII-MUGEN Immunology Summer School
April 14-21, 2007, Capo Caccia, Sardinia, Italy
Translation elongation factor EF-Tu is a target for Stp, a novel serine-threonine phosphatase of Listeria monocytogenes
13th International Conference on Bacilli «Functional Genomics of Gram-positive Microorganisms»
June 12-16, 2005, San Diego, California, USA
Role of the serine-threonine phosphatase Stp in the infectious process of Listeria monocytogenes
Vème colloque «Phosphorylation des protéines» (Société Française de Biochimie et Biologie Moléculaire)
September 26-29, 2004, Presqu’île de Giens, France