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Subvertion of host cell functions by Listeria
SUMOylation
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D. Ribet et al. (2010). Nature 464:1192-1195 Decrease in SUMO-conjugated proteins upon infection with Listeria. a) Comparison of SUMO-conjugated protein patterns from uninfected HeLa cells (2) or cells infected for 1, 3 or 5 h with L. monocytogenes (L.m.) or L. innocua (L.i.). Whole-cell lysates were analysed by immunoblotting experiments using antibodies specific for SUMO1 (upper panel) or SUMO2/3 (lower panel) isoforms. b) Analysis of SUMO1-conjugated protein patterns from uninfected HeLa cells (2) or cells infected for 3 h with wild-type (WT), DinlB or Dhly L. monocytogenes. c) Analysis of SUMO1- and SUMO2/3-conjugated protein patterns from HeLa cells incubated with 3nM LLO for 20 min. |
