Identification et caractérisation de nouveaux facteurs de virulence de Listeria monocytogenes
H. Bierne, Adapted from S.K. Mazmanian
L. monocytogenes expresses surface proteins that have critical roles in host-bacterium interactions. Surface proteins harboring a C-terminal sorting signal with an LPXTG motif are covalently linked to the cell wall peptidoglycan by a transamidase named sortase. Two genes encoding putative sortases, termed srtA and srtB, were identified in the Listeria genome.