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Identification et caractérisation de nouveaux facteurs de virulence de Listeria monocytogenes

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J. Johansson,et al. (2002). Cell, 110 : 551-561.

Regulation of PrfA expression. The untranslated region of the mRNA encoding PrfA can adopt at low temperatures a secondary structure that hides the ribosome binding site and prevents translation. This structure melts at high temperatures, allowing PrfA expression and consequently virulence gene expression.