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Biologie cellulaire de l'infection par <i>Listeria monocytogenes</i>
Motilité intra-cellulaire
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Figure from Pizarro-Cerda J, Cossart P. J Pathol. 2006 Jan;208(2):215-23. Figure 5. Polymerization of actin comet tails by ActA. A. The proline-rich sequence of ActA recruits VASP, which in turn recruits profilin and actin monomers that will be polymerized by the Arp2/3 complex, leading to the formation of actin comet tails that power the movement of L. monocytogenes in the host cell cytoplasm. B. Immunofluorescence showing the actin cytoskeleton (green) of kangaroo PTK2 and the polymerization of actin comet tails by L. monocytenes (red). |