Publications principales

Judith D, Mostowy S, Bourai M, Gangneux N, Lelek M, Lucas-Hourani M, Cayet N, Jacob Y, Prévost MC, Pierre P, Tangy F, Zimmer C, Vidalain PO, Couderc T, Lecuit M.
Species-specific impact of the autophagy machinery on Chikungunya virus infection.
EMBO Rep. 2013 Apr 26.
Link to Pubmed

Chenal-Francisque V, Diancourt L, Cantinelli T, Passet V, Tran-Hykes C, Bracq-Dieye H, Leclercq A, Pourcel C, Lecuit M, Brisse S.
Optimized Multilocus Variable-Number Tandem-Repeat Analysis Assay and Its Complementarity with Pulsed-Field Gel Electrophoresis and Multilocus Sequence Typing for Listeria monocytogenes Clone Identification and Surveillance.
J Clin Microbiol. 2013 Jun;51(6):1868-80.
Link to Pubmed

Schilte C, Staikovsky F, Couderc T, Madec Y, Carpentier F, Kassab S, Albert ML, Lecuit M, Michault A.
Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study.
PLoS Negl Trop Dis. 2013 Mar;7(3):e2137.
Link to Pubmed

Travier L, Guadagnini S, Gouin E, Dufour A, Chenal-Francisque V, Cossart P, Olivo-Marin JC, Ghigo JM, Disson O, Lecuit M.
ActA promotes Listeria monocytogenes aggregation, intestinal colonization and carriage.
PLoS Pathog. 2013 Jan;9(1):e1003131.
Link to Pubmed

Archambaud C, Nahori MA, Soubigou G, Bécavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P.
Impact of lactobacilli on orally acquired listeriosis.
Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16684-9
Link to Pubmed


Bierne H, Travier L, Mahlakõiv T, Tailleux L, Subtil A, Lebreton A, Paliwal A, Gicquel B, Staeheli P, Lecuit M, Cossart P.
Activation of Type III Interferon Genes by Pathogenic Bacteria in Infected Epithelial Cells and Mouse Placenta.
PLoS One. 2012;7(6):e39080.
Link to Pubmed

Couderc T, Gangneux N, Chrétien F, Caro V, Le Luong T, Ducloux B, Tolou H, Lecuit M, Grandadam M.
Chikungunya Virus Infection of Corneal Grafts.
J Infect Dis. 2012 Sep 15;206(6):851-9
Link to Pubmed

Clavarino G, Cláudio N, Couderc T, Dalet A, Judith D, Camosseto V, Schmidt EK, Wenger T, Lecuit M, Gatti E, Pierre P.
Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.
PLoS Pathog. 2012 May;8(5):e1002708.
Link to Pubmed

Mailles A, De Broucker T, Costanzo P, Martinez-Almoyna L, Vaillant V, Stahl JP; Steering Committee and Investigators Group.
Long-term outcome of patients presenting with acute infectious encephalitis of various causes in France.
Clin Infect Dis. 2012 May;54(10):1455-64.
Link to Pubmed

Disson O, Lecuit M.
Targeting of the central nervous system by Listeria monocytogenes.
Virulence. 2012 Mar 1;3(2):213-21. 
Link to Pubmed

Clavarino G, Cláudio N, Dalet A, Terawaki S, Couderc T, Chasson L, Ceppi M, Schmidt EK, Wenger T, Lecuit M, Gatti E, Pierre P.
Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells.
Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3006-11. 
Link to Pubmed

Bouraï M, Lucas-Hourani M, Gad HH, Drosten C, Jacob Y, Tafforeau L, Cassonnet P, Jones LM, Judith D, Couderc T, Lecuit M, André P, Kümmerer BM, Lotteau V, Desprès P, Tangy F, Vidalain PO.
Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component.
J Virol. 2012 Mar;86(6):3121-34. 
Link to Pubmed

Charlier C, Leclercq A, Cazenave B, Desplaces N, Travier L, Cantinelli T, Lortholary O, Goulet V, Le Monnier A, Lecuit M.
Listeria monocytogenes-associated joint and bone infections: a study of 43 consecutive cases.
Clin Inf Dis 2012 Jan 15;54(2):240-8.

Link to Pubmed

Nikitas G, Deschamps C, Disson O, Niault T, Cossart P, Lecuit M.
Transcytosis of Listeria monocytogenes across the intestinal barrier upon specific targeting of goblet cell accessible E-cadherin.
J Exp Med 2011 Oct 24;208(11):2263-77.

Link to Pubmed

Sauvage V, Foulongne V, Cheval J, Ar Gouilh M, Pariente K, Dereure O, Manuguerra JC, Richardson J, Lecuit M, Burguiere A, Caro V, Eloit M.
Human polyomavirus related to african green monkey lymphotropic polyomavirus.
Emerg Infect Dis 2011;17:1364-70.
Link to Pubmed

Sauvage V, Cheval J, Foulongne V, Gouilh MA, Pariente K, Manuguerra JC, Richardson J, Dereure O, Lecuit M, Burguiere A, Caro V, Eloit M.
Identification of the first human gyrovirus, a virus related to chicken anemia virus.
J Virol 2011;85:7948-50.
Link to Pubmed

Reynders A, Yessaad N, Vu Manh TP, Dalod M, Fenis A, Aubry C, Nikitas G, Escaliere B, Renauld JC, Dussurget O, Cossart P, Lecuit M, Vivier E, Tomasello E.
Identity, regulation and in vivo function of gut NKp46(+)RORgammat(+) and NKp46(+)RORgammat(-) lymphoid cells.
EMBO J 2011;30:2934-47.
Link to Pubmed

Chenal-Francisque V, Lopez J, Cantinelli T, Caro V, Tran C, Leclercq A, Lecuit M, Brisse S.
Worldwide distribution of major clones of Listeria monocytogenes.
Emerg Infect Dis 2011;17:1110-2.
Link to Pubmed

Mostowy S, Bonazzi M, Hamon MA, Tham TN, Mallet A, Lelek M, Gouin E, Demangel C, Brosch R, Zimmer C, Sartori A, Kinoshita M, Lecuit M, Cossart P.
Entrapment of intracytosolic bacteria by septin cage-like structures.
Cell Host Microbe. 2010 Nov 18;8(5):433-44.
Link to Pubmed

Tazi A, Disson O, Bellais S, Bouaboud A, Dmytruk N, Dramsi S, Mistou MY, Khun H, Mechler C, Tardieux I, Trieu-Cuot P, Lecuit M*, Poyart C*.
The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates.
J Exp Med. 2010 Oct 25;207(11):2313-22.

Link to Pubmed

Decaudin D, Ferroni A, Vincent-Salomon A, Beldjord K, Validire P, de Cremoux P, Validire P, Plancher C, Mathiot C, Macintyre E, Asselain B, Girodet J, Mal F, Brousse N, Beretti JL, Dendale R, Lumbroso-Le Rouic L, Hermine O, Lecuit M.
Ocular adnexal lymphoma and Helicobacter pylori gastric infection.
Am J Hematol. 2010 May 23.
Link to Pubmed

Morvan A, Moubareck C, Leclercq A, Hervé-Bazin M, Bremont S, Lecuit M, Courvalin P, Le Monnier A.
Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in France.
Antimicrob Agents Chemother. 2010 Jun;54(6):2728-31.
Link to Pubmed

Personnic N, Bruck S, Nahori MA, Toledo-Arana A, Nikitas G, Lecuit M, Dussurget O, Cossart P, Bierne H.
The stress-induced virulence protein InlH controls interleukin-6 production during murine listeriosis.
Infect Immun. 2010 May;78(5):1979-89.
Link to Pubmed

Schilte C*, Couderc T*, Chretien F, Sourisseau M, Gangneux N, Guivel-Benhassine F, Kraxner A, Tschopp J, Higgs S, Michault A, Arenzana-Seisdedos F, Colonna M, Peduto L, Schwartz O, Lecuit M*, Albert ML*.
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells.
J Exp Med. 2010 Feb 15;207(2):429-42.
Link to Pubmed

Lemichez E, Lecuit M, Nassif X, Bourdoulous S.

Breaking the wall: targeting of the endothelium by pathogenic bacteria.
Nat Rev Microbiol. 2010 Feb;8(2):93-104. Review.
Link to Pubmed

Guillet C, Join-Lambert O, Monnier AL, Leclercq A, Mechai F, Mamzer-Bruneel MF, Bielecka MK, Scortti M, Disson O, Berche P, Vazquez-Boland J, Lortholary O, Lecuit M.

Human Listeriosis Caused by Listeria ivanovii.
Emerg Infect Dis. 2010 Jan;16(1):136-138.
Link to Pubmed

Mailles A, Stahl JP; Steering Committee and Investigators Group.
Infectious encephalitis in france in 2007: a national prospective study.
Clin Infect Dis. 2009 Dec 15;49(12):1838-47.
Link to Pubmed

Leclercq A, Clermont D, Bizet C, Grimont PA, Le Flèche-Matéos A, Roche SM, Buchrieser C, Cadet-Daniel V, Le Monnier A, Lecuit M, Allerberger F.
Listeria rocourtiae sp. nov.
Int J Syst Evol Microbiol. 2009 Nov 13. [Epub ahead of print]
Link to Pubmed

Staikowsky F, Talarmin F, Grivard P, Souab A, Schuffenecker I, Le Roux K, Lecuit M, Michault A.
Prospective study of Chikungunya virus acute infection in the Island of La Réunion during the 2005-2006 outbreak.
PLoS One. 2009 Oct 28;4(10):e7603.
Link to Pubmed

Bonazzi M, Lecuit M, Cossart P.
Listeria monocytogenes internalin and E-cadherin: from bench to bedside.
Cold Spring Harb Perspect Biol. 2009 Oct;1(4):a003087.
Link to Pubmed

Charlier-Woerther C, Leclercq A, Lortholary O, Lecuit M.
[Listeriosis, a rare but severe foodborne infection].
Rev Prat. 2009 Sep 20;59(7):905-11. French.

Link to Pubmed

Couderc T, Lecuit M.
Focus on Chikungunya pathophysiology in human and animal models.
Microbes Infect. 2009 Dec;11(14-15):1197-205.

Link to Pubmed

Couderc T, Khandoudi N, Grandadam M, Visse C, Gangneux N, Bagot S, Prost JF, Lecuit M.
Immunoprophylaxis and therapy for Chikungunya virus infection.
J Infect Dis. 2009, Aug 15;200(4):516-523.
Link to Pubmed

Levraud JP, Disson O, Kissa K, Bonne I, Cossart P, Herbomel P, Lecuit M.
Real-time observation of Listeria-phagocyte interactions in the living zebrafish larva.
Infect Immun. 2009, Sep;77(9):3651-60.

Link to Pubmed

Toledo-Arana A, Dussurget O, Nikitas G, Sesto N, Guet-Revillet H, Balestrino D, Loh E, Gripenland J, Tiensuu T, Vaitkevicius K, Barthelemy M, Vergassola M, Nahori MA, Soubigou G, Régnault B, Coppée JY, Lecuit M, Johansson J, Cossart P.
The Listeria transcriptional landscape from saprophytism to virulence.
Nature. 2009 Jun 18;459(7249):950-6.
Link to Pubmed

Disson O, Nikitas G, Grayo S, Dussurget O, Cossart P, Lecuit M.
Human listeriosis modeling in natural and genetically engineered animals.
Nature Protoc. 2009, 4(6):799-810.
Link to Pubmed

Bonazzi M, Lecuit M, Cossart P.
Listeria monocytogenes internalin and E-cadherin: from structure to pathogenesis.
Cell Microbiol. 2009 Feb 2.
Link to Pubmed

Disson O, Grayo S, Huillet E, Nikitas G, Langa-Vives F, Dussurget O, Ragon M, Le Monnier A, Babinet C, Cossart P, Lecuit M.

Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis.
Nature. 2008 Oct 23;455(7216):1114-8.

Ragon M, Wirth T, Hollandt F, Lavenir R, Lecuit M, Le Monnier A, Brisse S.

A new perspective on Listeria monocytogenes evolution.
PLoS Pathog. 2008 Sep 5;4(9):e1000146.

Cabanes D, Lecuit M, Cossart P.

Animal models of Listeria infection.
Curr Protoc Microbiol. 2008 Aug;Chapter 9:Unit9B.1.

Bréhin AC, Mouriès J, Frenkiel MP, Dadaglio G, Desprès P, Lafon M, Couderc T.

Dynamics of immune cell recruitment during West Nile encephalitis and identification of a new CD19+B220-BST-2+ leukocyte population.
J Immunol. 2008 May 15;180(10):6760-7.

Gérardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, Lenglet Y, Touret Y, Bouveret A, Grivard P, Le Roux K, Blanc S, Schuffenecker I, Couderc T, Arenzana-Seisdedos F, Lecuit M*, Robillard PY.
Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Réunion.
PLoS Med
. 2008 Mar 18;5(3):e60.

Link to the article

Couderc T, Chrétien F, Schilte C, Disson O, Brigitte M, Guivel-Benhassine F, Touret Y, Barau G, Cayet N, Schuffenecker I, Desprès P, Arenzana-Seisdedos F, Michault A, Albert ML, Lecuit M.

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease.
PLoS Pathog. 2008 Feb 8;4(2):e29.
Link to the article

Sabet C, Toledo-Arana A, Personnic N, Lecuit M, Dubrac S, Poupel O, Gouin E, Nahori MA, Cossart P, Bierne H.
The Listeria monocytogenes virulence factor InlJ is specifically expressed in vivo and behaves as an adhesin.
Infect Immun. 2008 Apr;76(4):1368-78. Epub 2008 Jan 28.
Link to Pubmed

Lecuit M.
Human listeriosis and animal models.
Microbes Infect. 2007 Aug;9(10):1216-25. Link to Pubmed

Sousa S, Cabanes D, Bougneres L, Lecuit M, Sansonetti P, Tran-Van-Nhieu G, Cossart P.
Src, cortactin and Arp2/3 complex are required for E-cadherin-mediated internalization of Listeria into cells.
Cell Microbiol. 2007 Jul 11
Link to Pubmed

Lecuit M, Sonnenburg JL, Cossart P, Gordon JI.
Functional genomic studies of the intestinal response to a foodborne enteropathogen in a humanized gnotobiotic mouse model.
J Biol Chem. 2007 May 18;282(20):15065-72.
Link to Pubmed

Boneca IG, Dussurget O, Cabanes D, Nahori MA, Sousa S, Lecuit M, Psylinakis E, Bouriotis V, Hugot JP, Giovannini M, Coyle A, Bertin J, Namane A, Rousselle JC, Cayet N, Prevost MC, Balloy V, Chignard M, Philpott DJ, Cossart P, Girardin SE.
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):997-1002.
Link to Pubmed

Khelef N, Lecuit M, Bierne H, Cossart P.
Species specificity of the Listeria monocytogenes InlB protein.

Cell Microbiol. 2006 Mar;8(3):457-70. Link to Pubmed

Khelef, N, Lecuit, M, Buchrieser, C, Cabanes, D, Dussurget, O, and Cossart, P.
L. monocytogenes
and the genus Listeria. In: The Prokaryotes.
A Handbook on the Biology of Bacteria, 2006. 3rd. ed. Vol. 4. Dworkin, Falkow, Rosenberg, Schleifer, & Stackebrandt (Eds.), Springer, New York, USA. 

Sousa S, Cabanes D, Archambaud C, Colland F, Lemichez E, Popoff M, Boisson-Dupuis S, Gouin E, Lecuit M, Legrain P, Cossart P.
ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion.
Nat Cell Biol. 2005 Oct;7(10):954-960. Link to PubMed

Sabet C, Lecuit M, Cabanes D, Cossart P, Bierne H.
LPXTG protein InlJ, a newly identified internalin involved in Listeria monocytogenes virulence.
Infect Immun. 2005 Oct;73(10):6912-22. Link to PubMed

Cabanes D, Sousa S, Cebria A, Lecuit M, Garcia-del Portillo F, Cossart P.
Gp96 is a receptor for a novel Listeria monocytogenes virulence factor, Vip, a surface protein.
EMBO J. 2005 Aug 3;24(15):2827-38. Link to PubMed

Lecuit M, Cossart P.
[Molecular basis of Listeria monocytogenes fetoplacental tropism]
Med Sci (Paris). 2005 Jan;21(1):17-9. French. Link to PubMed

Sousa S, Lecuit M, Cossart P.
Microbial strategies to target, cross or disrupt epithelia.
Curr Opin Cell Biol. 2005 Oct;17(5):489-98. Link to PubMed

Dramsi S, Bourdichon F, Cabanes D, Lecuit M, Fsihi H, Cossart P.
FbpA, a novel multifunctional Listeria monocytogenes virulence factor.
Mol Microbiol. 2004 Jul;53(2):639-49.
Link to PubMed

Jacquet C, Doumith M, Gordon JI, Martin PM, Cossart P, Lecuit M.
A molecular marker for evaluating the pathogenic potential of foodborne Listeria monocytogenes.
J Infect Dis. 2004 Jun 1;189(11):2094-100.
Link to PubMed

Sousa S, Cabanes D, El-Amraoui A, Petit C, Lecuit M, Cossart P.
Unconventional myosin VIIa and vezatin, two proteins crucial for Listeria entry into epithelial cells.
J Cell Sci. 2004 Apr 15;117(Pt 10):2121-30. Link to PubMed

Lecuit M, Nelson DM, Smith SD, Khun H, Huerre M, Vacher-Lavenu MC, Gordon JI, Cossart P.
Targeting and crossing of the human maternofetal barrier by Listeria monocytogenes: role of internalin interaction with trophoblast E-cadherin.
Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6152-7. Link to PubMed


Cossart P, Pizarro-Cerda J, Lecuit M.
Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions.
Trends Cell Biol. 2003 Jan;13(1):23-31. Review. Link to PubMed

Dussurget O, Cabanes D, Dehoux P, Lecuit M, Buchrieser C, Glaser P, Cossart P; European Listeria Genome Consortium.
Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis.
Mol Microbiol. 2002 Aug;45(4):1095-106.
Link to PubMed

Lecuit M, Vandormael-Pournin S, Lefort J, Huerre M, Gounon P, Dupuy C, Babinet C, Cossart P.
A transgenic model for listeriosis: role of internalin in crossing the
intestinal barrier.
Science. 2001 Jun 1;292(5522):1722-5.
Link to PubMed

Kussel-Andermann P, El-Amraoui A, Safieddine S, Nouaille S, Perfettini I, Lecuit M, Cossart P, Wolfrum U, Petit C.
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex.
EMBO J. 2000 Nov 15;19(22):6020-9.
Link to PubMed

Lecuit M, Hurme R, Pizarro-Cerda J, Ohayon H, Geiger B, Cossart P.
A role for alpha-and beta-catenins in bacterial uptake.
Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10008-13.
Link to PubMed

Lecuit M, Dramsi S, Gottardi C, Fedor-Chaiken M, Gumbiner B, Cossart P.
A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes.
EMBO J. 1999 Jul 15;18(14):3956-63.
Link to PubMed

Cossart P, Lecuit M.
Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signaling.
EMBO J. 1998 Jul 15;17(14):3797-806. Review.
Link to PubMed

Lecuit M, Ohayon H, Braun L, Mengaud J, Cossart P.
Internalin of Listeria monocytogenes with an intact leucine-rich repeat region
is sufficient to promote internalization.
Infect Immun. 1997 Dec;65(12):5309-19. 
Link to PubMed

Mengaud J, Lecuit M, Lebrun M, Nato F, Mazie JC, Cossart P.
Antibodies to the leucine-rich repeat region of internalin block entry of
Listeria monocytogenes into cells expressing E-cadherin.
Infect Immun. 1996 Dec;64(12):5430-3.
Link to PubMed