Genome Analysis 2011-2012
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Directors : Pr Bernard Dujon Yeast Molecular Genetics Unit, Institut Pasteur Dr Odile Ozier-Kalogeropoulos Yeast Molecular Genetics Unit, Institut Pasteur Heads of Studies : Dr Lionel Frangeul Genome Analysis and Integration, Institut Pasteur |
Candidates must have a good knowledge of genetics, molecular biology and biochemistry, equivalent to a Master level.
This course will be taught in French.
The specificity of the course consists in combining bench practical work with an in-depth in silico analysis of genomics data.
Lectures will address the fundamental aspects of genomics (structure and comparison of genomes, human genomics, transcriptome analysis…), examples of medical and biotechnological applications.
In silico classes will include:
- Use of computing tools, analysis of genome sequences and annotations, comparative genomics,
- Polymorphism analysis of the human genome for evolution history and for candidate gene approach in genetic disorders.
From the Bench to Data Analysis:
- Genome microevolution of Chikungunya virus,
- Study of the primary transcriptome of Streptococcus agalactiae by RNA-seq approach in different strains,
- Analysis of DNA polymorphisms in the gene lactase and in the mitochondrial genome in human populations.
Full-time, November 02, to December 16, 2011 (examinations included)
Number of students: 20
Closing-date for applications: June 15, 2011
Laboratory courses:
Laboratory courses are organized by:
- Unit of Human Evolutionary Genetics
- Laboratory “Bacterial Evolution and Genomics”
- Pasteur Genopole: “Bioinformatics for Genome Analysis”, “Transcriptome and Epigenome”
- Group “Bioinformatics Development and Projects”
- Platform “Genotyping of Pathogens and Public Health”
Lecturers (preliminary list):
L. Abel, H. De Reuse, D. Ehrlich, A. Jacquier, S. Jamain, G. Lelandais, B. Llorente, C. Medigue, C. Neuveglise, L. Orlando, E. Quach, L. Quintana-Murci, E. Patin, B. Régnault, H. Roest-Crollius, J.P. Rousset, T. Vallaeys, S. Wain-Hobson and P. Wincker.
Diplomas:
- The Institut Pasteur Diploma will be awarded to students having successfully completed the examinations
- This course is run in agreement with the Université Pierre et Marie Curie and the Université Paris-Diderot and a University Diploma may also be granted
- Credits for Master’s (second year) from Universités Paris-Descartes, Pierre et Marie Curie, Paris-Diderot, Orsay-Paris11 and Versailles Saint-Quentin, for students registered in one of these universities
- Module(s) from Doctoral Schools
Members of the Teaching Committee:
E. Coeffier (Institut Pasteur), A. Ducruix* (Faculté de Pharmacie, Université Paris-Descartes), B. Dujon (Institut Pasteur/Université P. et M. Curie), R.A. Veitia* (Université Paris-Diderot), F. Devaux* (Ecole normale supérieure/Université P. et M. Curie), J. Heuvingh (Université Paris-Diderot), H. de Reuse (Institut Pasteur), B. Ladoux (Université Paris-Diderot), O. Ozier-Kalogeropoulos (Institut Pasteur/Université P. et M. Curie), C. Parsot (Institut Pasteur).
* University Representatives