Cellular and Molecular Genetics 2012-2013

Directors : Dr Benoît Arcangioli Genome Dynamics Unit, Institut Pasteur Pr Thomas Bourgeron Human Genetics and cognitive Functions Group, Institut Pasteur and Université Paris-Diderot Pr Michèle Debatisse, Institut Curie Head of Studies : Dr Sophie Bachellier-Bassi Fungal Biology and Pathogenicity Unit, Institut Pasteur

 

Candidates must have good knowledge of Genetics at the Master level.
The main language used in this course is French, but some lectures are in English.

The aim of the course is to introduce students to technical and conceptual aspects of research in modern somatic cell and germ-line Genetics, from yeast to human.
Theoretical courses will address the organisation and expression of the eukaryotic genome as well as the organization and expression of molecular and cellular mechanisms which maintain genome integrity. The focus will be on genetic and epigenetic processes and their influence in normal and pathological development of germ-line and somatic cells.
Practical courses will include: analysis of a chromosomal fragile site by DNA combing and cytogenetic; Deletion of a transcription factor in yeast, microarray analysis of the transcriptome in different growth conditions and phenotypic analysis of corresponding mutants; chromatin immunoprecipitation (ChIP) ; Bioinformatics ;multifactorial Genetics ; human genetics and analysis of CNVs (Copy Number Variations) and SNPs (Single Nucleotide Polymorphisms).


* Full-time, Saturdays included, from November 5, to December 21, 2012 (examinations included)
* Number of students: 24
* Closing-date for applications: June 15, 2012

Diplomas:

The Institut Pasteur Diploma will be awarded to students having successfully completed the final examination,

This course is run in agreement with the Université Pierre et Marie Curie and Paris Diderot-Paris 7 and a University Diploma may also be granted,

Credits for Masters (second year) from Universités René Descartes, Pierre et Marie Curie and Paris Diderot-Paris 7,  for students registered at this universities (masters).

 

Members of the Teaching Committee:

B. Arcangioli (Institut Pasteur), S. Bachellier-Bassi (Institut Pasteur), A. Bernheim (Institut Gustave Roussy), T. Bourgeron (Institut Pasteur/ Université Paris Diderot), E. Coeffier (Institut Pasteur), M. Debatisse* (Université P. et M. Curie), J. Heuvingh (Université Paris-Diderot), B. Ladoux (Université Paris Diderot), S. Le Crom (Ecole Normale Supérieure), C. Parsot (Institut Pasteur), D. Scott-Algara (Institut Pasteur) and F. Schweisguth (Ecole Normale Supérieure). 

* University Representatives

Lecturers:

B. Arcangioli, A. Bernheim,W. Bickmore, S. Boiteux, B. Caudron, JY Coppée, F. Dautry, M. Debatisse-Buttin, C. Fairhead, F. Fauchereau, E. Gilson, S. Gribaldo, E. Heard, O. Hyrien, K. McElreavey, V. Malan, C. Muchardt, C. Nguyen, J.-J. Panthier, M. Perrière; L. Quintana-Murci, R. Rothstein, A. Sarasin, V. Simanis, I. Solovei, S. Tajbakhsh, R. Veitia, J-P. Villartay and D. Zickler.