Advanced Immunology
| Directors : Dr Andrès Alcover Lymphocyte Cell Biology Unit, Institut Pasteur Pr Antonio Freitas Lymphocyte Population Biology Unit, Institut Pasteur Head of Studies : Dr François Huetz Lymphocyte Population Biology Unit, Institut Pasteur |
Candidates must have good knowledge of Biochemistry, Molecular Biology and Genetics as well as a first year Master level in Immunology (or equivalent).
This course will be taught in English. (Students should have enough knowledge of English language to understand full lectures in English, ask questions and deliver a bibliography analysis seminar). Understanding of French language is useful for daily interactions.
• Two weeks of lectures dealing with advanced studies on the main themes in cellular and molecular Immunology: development of the immune system, lymphocyte differentiation, molecular basis of antigen recognition by B and T lymphocytes, repertoire selection, lymphocyte homeostasis, tolerance, cellular communication, immune responses, innate immunity and immunopathology
• Three weeks of laboratory practical course focusing on the characterization of two functions of the AID protein (Activation Induced Cytidine Deaminase) in B cells: isotypic switch and somatic hypermutation. These roles of AID will be studied in B cells from wild type or AID-KO mice by FACS, ELISA analyses, by reporter gene transfection assays, siRNA, sequence of genes undergoing somatic hypermutation and real-time PCR. Some experiments are carried out in the BSL2+ facility of the Institut Pasteur Center for Human Immunology. Updated Tetanos and Hepatitis B vaccination certificates are required to acces these facilities.
Full-time, Saturdays included, from November 19, 2012 to January 11, 2013
From November 19, to December 22, 2012 for students following the Institut Pasteur Course only (including exam).
The students enrolled in University Master Programs will have the exam and the thematic bibliography seminars from January 7 to 11, 2013.
Number of students: 24
Closing-date for applications: June 15, 2012 (online registration)
Tuition fees
Diplomas:
The Institut Pasteur Diploma will be awarded to students having successfully completed the final examination,
This course is run in agreement with the Université Pierre et Marie Curie and Paris-Diderot and a University Diploma may also be granted,
Credits for Masters (second year) from Universités Paris-Descartes, Pierre et Marie Curie and Paris-Diderot, for students registered at this universities (masters).
Students enrolled in Immunology Programs: Advanced Immunology (Immunologie Approfondie) or Physiopathology of Immune Responses will follow two weeks of “Introduction to Immunology” at the University before starting the Institut Pasteur course.
Doctoral School Modules.
Members of the Teaching Committee:
A. Alcover (Institut Pasteur), P. A. Cazenave (Institut Pasteur/Université P. et M. Curie), E. Coeffier (Institut Pasteur), A. Freitas (Institut Pasteur), C. Fridman* (Université Paris-Descartes), F. Huetz (Institut Pasteur), C. Parsot (Institut Pasteur), A. Six* (Université P. et M. Curie), M. Viguier* (Université Paris-Diderot), A. Zider (Université Paris-Diderot).
* University Representatives
Lecturers:(preleminary list)
M. Albert, A. Alcover, A. Bandeira, T. Boehm, I. Boneca C. Bourgeois, P. Bousso, M. Cavazzana-Calvo, A. Cumano, G. Dadaglio, M. Daëron, V. Di Bartolo, J. Di Santo, L. Du Pasquier, G. Eberl, A. Fischer, A. Freitas, M. Goodhardt, A. Hayday, M. Heikenwaelder, L. Klein, R. Lasserre, C. Leclerc, J. P. Levraud, L. Majlessi, R. Mebius, P. Pereira, J. M. Reichhart, C. A. Reynaud, B. Rocha, H.-R. Rodewald, O. Schwartz, C. Tanchot, J. P. de Villartay, N. Van Baren, M. Veldhoen, C. Vosshenrich.
