Teaching / Mechanisms of Living Organisms

Advanced Immunology 2011-2012


 
Directors :
Dr Andrès Alcover
Lymphocyte Cell Biology Unit,
Institut Pasteur


Pr Antonio Freitas
Lymphocyte Population Biology Unit,
Institut Pasteur


Head of Studies :
Dr François Huetz
Antiviral Cell Immunology Unit,
Institut Pasteur

 

Candidates must have good knowledge of Biochemistry, Molecular Biology and Genetics as well as a first year Master level in Immunology (or equivalent).

This course will be taught in English.

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• Two weeks of lectures dealing with advanced studies on the main themes in cellular and molecular Immunology: development of the immune system, lymphocyte differentiation, molecular basis of antigen recognition by B and T lymphocytes, repertoire selection, lymphocyte homeostasis, tolerance, cellular communication, immune responses, innate immunity and immunopathology.

• Three weeks of laboratory practical course focusing on the characterization of two functions of the AID protein (Activation Induced Cytidine Deaminase) in B cells: isotypic switch and somatic hypermutation. These roles of AID will be studied in B cells by FACS, ELISA and ELISPOT analyses, by reporter gene transfection assays, siRNA and sequence of genes undergoing somatic hypermutation.

 • Three days of thematic bibliography seminars, given by groups of students and supervised by two senior scientists.  These seminars are mandatory for students enrolled in Master programs and optional for students following the Institut Pasteur Course only.

Full-time, Saturdays included, from November 14, 2011 to January 6, 2012

From November 14, to December 17, 2011 for students following the Institut Pasteur Course only (including exam).
The students enrolled in University Master Programs will have the exam and the thematic bibliography seminars from January 3 to 6, 2012.

Number of students: 24

Closing-date for applications: June 15, 2011


Diplomas:

The Institut Pasteur Diploma will be awarded to students having successfully completed the final examination,

This course is run in agreement with the Université Pierre et Marie Curie and Paris-Diderot and a University Diploma may also be granted,

Credits for Masters (second year) from Universités Paris-Descartes, Pierre et Marie Curie and Paris-Diderot,  for students registered at this universities (masters).

Students enrolled in Immunology Programs: Advanced Immunology (Immunologie Approfondie) or Physiopathology of Immune Responses will follow two weeks of “Introduction to Immunology” at the University before starting the Institut Pasteur course.

Doctoral School Modules.

 

Members of the Teaching Committee:

 

A. Alcover (Institut Pasteur), P. A. Cazenave (Institut Pasteur/Université P. et M. Curie), E. Coeffier (Institut Pasteur), A. Freitas (Institut Pasteur), C. Fridman* (Université Paris-Descartes), F. Huetz (Institut Pasteur), O. Ozier-Kalogeropoulos (Institut Pasteur/Université P. et M. Curie), C. Parsot (Institut Pasteur), A. Six* (Université P. et M. Curie), M. Viguier* (Université Paris-Diderot), A. Zider (Université Paris-Diderot).
* University Representatives

Lecturers:(preleminary list)

M. Albert, A. Alcover, A. Bandeira, T. Boehm, I. Boneca C. Bourgeois, P. Bousso, M. Cavazzana-Calvo, A. Cumano, G. Dadaglio, M. Daëron, V. Di Bartolo, J. Di Santo, L. Du Pasquier, G. Eberl, A. Fischer, A. Freitas, M. Goodhardt, A. Hayday, M. Heikenwaelder, L. Klein, R. Lasserre, C. Leclerc, J. P. Levraud, L. Majlessi, R. Mebius, P. Pereira, J. M. Reichhart, C. A. Reynaud, B. Rocha, H.-R. Rodewald, O. Schwartz, C. Tanchot, J. P. de Villartay, N. Van Baren, M. Veldhoen, C. Vosshenrich.