Medical Mycology Course
Pr Françoise Dromer
Molecular Mycology Unit,
and National Reference Center for Mycoses and Antifungal Agents,
Pr Olivier Lortholary
Hopital Necker Enfants Malades and National Reference Center for Mycoses and Antifungal Agents, Institut Pasteur
Head of Studies :
Dr Dea Garcia Hermoso
Molecular Mycology Unit,and National Reference Center for Mycoses and Antifungal Agents, Institut Pasteur
This four-week course is aimed at MDs, PhDs or veterinarians, working in a hospital microbiology laboratory and having previous practice of medical mycology, who are willing to improve their practical and theoretical knowledge in the field.
Training is provided through bench works, lectures and panel discussions and will cover:
- Technical aspects: choice of media, slide cultures, storage of isolates, molecular diagnosis and identification (PCR, qPCR, sequencing, MALDI-TOF), typing techniques (microsatellite, MLST), antifungal susceptibility testing (CLSI/EUCAST microbroth dilution methods, commercially available tests), antigen/antibody detection, histopathology.
- Practical aspects: spectrum of action and pharmacokinetics/dynamics of antifungal drugs, role of the laboratory in the diagnosis and monitoring of patients (direct examination, histopathology, antigen detection, antifungal susceptibility testing results, qPCR …), limitation and use of public and specific databases for molecular identification, discussion of clinical cases.
- Fungal aspects: sexual and asexual reproduction, phylogeny, species identification, resistance mechanisms.
- Medical aspects: Pathogenic concepts, epidemiology diagnosis criteria for infections due to common and emerging yeasts or filamentous fungi (including invasive and mucocutaneous infections, endemic mycoses), principles of therapeutic management, practical guidelines.
The program of the course organized in 2012 can be downloaded to get detailed information on the general frame of the course; some topics and practical works change, however, the aims and the general means of the course are maintained.
Full time, March 3rd to 28th, 2014 (Examinations included)
Number of students: 20
Closing-date for applications: september 30th, 2013 (online registration)
The Institut Pasteur Diploma will be awarded to students having successfully completed the final examination,
This course is run in agreement with the Université Pierre et Marie Curie-Paris 6 and Paris-Diderot and a University Diploma may also be granted,
12 ECTS for students registered in Master’s training in Public Health - Pasteur/ Cnam of Public Health
Members of the Teaching Committee: E. Coeffier (Institut Pasteur), F. Dromer (Institut Pasteur), J. Dupouy-Camet (Faculté de Médecine Paris-Descartes- Hôpital Cochin), J.-P. Gangneux CHU Rennes), D. Garcia Hermoso-Kaiser (Institut Pasteur), O. Lortholary (Université Paris-Descartes, Hôpital Necker-Enfants Malades et Institut Pasteur), C. Parsot (Institut Pasteur), P. Silar* (Université Paris-Diderot Paris 7).* University Representatives`
Lecturers: M. Arendrup (Denmark), J. Bille (Switzerland), T. Boekhout (The Netherlands), S. Bretagne (France), A. van Belkum (The Netherlands), T. Calandra (Switzerland), F. Chrétien (France), JM Costa (France), M. Cuenca-Estrella (Spain), D.W. Denning (UK), J. Dupont (France), F. Dromer (France), J.-P. Gangneux (France), D. Garcia-Hermoso (France), J. Guillot (France), R. Hay (UK), W. Hope (UK), C. Klaassen (The Netherlands), O. Lortholary (France), M. Machouart (France), V. Robert (The Netherlands), A.Stchigel (Spain), P. Verweij (The Netherlands)