Molecular Retrovirology / Publications


 Suspène R, MM Aynaud, SK, D Pasedloup, M Labetoulle, JP Vartanian, A Meyerhans and S Wain-Hobson
Genetic editing of herpes simplex 1 and Epstein Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in vitro and in vivo.
Journal of Virology 85, 7594-7602 2011

Martínez JP, G Bocharov, A Ignatovich, J Reiter, MT Dittmar, S Wain-Hobson and A Meyerhans
Epistasis buffers HIV-1 fitness losses along an AZT-resistance pathway
PLoS One 6, e18375 2011

Suspène R*, MM Aynaud*, M Henry, D Guétard, G Eckhoff, JP Vartanian and S Wain-Hobson
Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases – a pathway for DNA catabolism .
Proc Natl Acad Sci, USA, 108, 4858-4863 2011

Suspène R, V Petit, Puyraimond-Zemmour, MM Aynaud, C Rusniok, S Wain-Hobson and JP Vartanian
Double stranded RNA adenosine deaminase ADAR-1 induced hypermuted genomes among inactivated seasonal influenza and live attenuated measles vaccines
Journal of Virology, 85,2458-2462 2011

Rusakiewicz S, M Dosset, K Mollier, P Souque, P Charneau, S Wain-Hobson, P Langlade-Demoyen and O Adotévi
Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice
Vaccine 28, 6374-6381 2010

Renard M, M Henry, D Guétard, JP Vartanian and S Wain-Hobson
APOBEC1 and APOBEC3 cytidine deaminases as restriction factors for hepadnaviral genomes in non-humans in vivo
Journal of Molecular Biology 400, 323-324 2010

Fan J, G Ma, K Nosaka, J Tanabe, Y Satou, A Koito, S Wain-Hobson, J-P Vartanian and M Matsuoka
APOBEC3G generates nonsense mutations in HTLV-1 proviral sequences
Journal of Virology 84, 7278-7287 2010

Vartanian JP, M Henry, A Marchio, R Suspène, MM Aynaud, D Guétard, M Cervantes-Gonzalez, C Battiston, V Mazzaferro, P Pineau, A Dejean and S Wain-Hobson
Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis
PLoS Pathogens 6, e1000928 2010

Adotevi O, K Mollier, C Neuveut, M Dosset, P Ravel, W-H Fridman, E Tartour, P Charneau, S Wain-Hobson and P Langlade-Demoyen
Targeting human telomerase reverse transcriptase (hTERT) with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo
Blood 115, 2025-3032 2010

Gonzalez MC, R Suspène, M Henry, D Guétard, S Wain-Hobson and JP Vartanian
Human APOBEC1 cytidine deaminase edits HBV DNA
Retrovirology 6, 96 2009

Murphy RL, B Autran, C Katlama, G Brucker, P Debré, V Calvez, B Clotet, N Clumeck, D Costagliola, SG Deeks, L Dorrel, J Gattel, A Haase, M Klein, A Lazzarin, AJ McMichael, L Papagno, TW Schacker, S Wain-Hobson, BD Walker and M Youle
A step ahead on the HIV collaboratory (letter)
Science 324, 1264-1265 2009

Kostrzak A, M Cervantes Gonzalez, D Guetard, D Bellary Nagaraju, S Wain-Hobson, D Tepfer, T Pniewski and M Sala
Oral administration of low doses of plant-based HBsAg induced antigen-specific IgAs and IgGs in mice, without increasing levels of regulatory T cells.
Vaccine 27, 4798-4807 2009

Domingo E and S Wain-Hobson
Quasisprcies’ 30th birthday
EMBO Reports 10, 444-448 2009

Henry M, D Guétard, R Suspène, C Rusniok, S Wain-Hobson and JP Vartanian
Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G
PLoS One4, e4277 2009

LaRue R, V Andrésdóttir, Y Blanchard, SG Conticello, D Derse, M Emerman, WC Greene, SR Jónsson, NR Landau, M Löchelt, HS Malik, MH Malim, C Münk, SJ O'Brien,VK Pathak, K Strebel, S Wain-Hobson, XiF Yu, N Yuhki and RS Harris
Guidelines for naming non-primate APOBEC3 genes and proteins
Journal of Virology 83, 494-497 2009

Petit V, D Guétard, A Keriel, M Sitbon, S Wain-Hobson and JP Vartanian
Murine APOBEC1 deaminates Fr-MLV RNA and DNA in vitro and in vivo
Journal of Molecular Biology 385, 65-78 2009

Petit V, JP Vartanian and S Wain-Hobson
Powerful mutators lurking in the genome
Philosophical Transactions of the Royal Society B 364, 705-715 2009

Guétard D, R Greco, M Cervantes-Gonzalez, S Celli, A Kostrzak, P Langlade-Demoyen, F Sala, S Wain-Hobson and M Sala
Immunogenicity and tolerance following HIV-1/HBV plant-based oral vaccine administration
Vaccine 26, 447-4485 2008

Wain-Hobson, S
Retrovirus evolution
In Origin and evolution of viruses (Eds. E Domingo, C Parrish & JJ Holland)
Academic Press pp259-277 2008

Suspène R, M Renard, M Henry, D Puyraimond-Zemmour, A Billecocq, M Bouloy, F Tangy, JP Vartanian and S Wain-Hobson
Inverting the natural hydrogen bonding rule to selectively amplify GC-rich ADAR edited RNAs
Nucleic Acids Research 36, e72 2008

Vartanian JP, D Guétard, M. Henry and S Wain-Hobson
Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and pre-cancerous lesions
Science 320, 230-233 2008

Greco R, M Michel, D Guetard, M Cervantes-Gonzalez, N Pelucchi, S Wain-Hobson, F Sala and M Sala
Production of recombinant HIV-1/HBV virus-like particles in Nicotiana tabacum and Arabidopsis thaliana plants for a bivalent vaccin
Vaccine 25, 8228-8240 2007

Sala M, M Centlivre and S Wain-Hobson
Clade-specific differences in active viral replication and compartmentalisation
Current Opinion in HIV/AIDS 1, 108-114 2007

Sester U, M Sester, H Köhler, HW Pees, BC Gärtner, S Wain-Hobson, G Bocharov and
A Meyerhans
The maintenance of HIV-specific central and effector memory CD4 and CD8 T cells requires antigen persistence
AIDS Research and Human Retroviruses 23, 549-553 2007

Terzian C, M Henry, A Meyerhans, S Wain-Hobson and JP Vartanian
Induction of mutations in D. melanogaster gypsy retroelements by modulation of intracellular deoxynucleoside triphosphate pools
Journal of Virology 81, 4900-4903 2007

Centlivre M, M Sala, S Wain-Hobson and B Berkhout
In HIV pathogenesis the die is cast in primary infection
AIDS 21, 1-11 2007

Michel M, Y-C Lone, M Centlivre, P Roux, S Wain-Hobson and M Sala
Optimisation of secretion of recombinant HBsAg virus-like articles: impact on the development of HIV-1/HBV bivalent vaccines
Vaccine 21, 1-11 2007

Suspène R, C Rusniok, JP Vartanian and S Wain-Hobson
Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication
Nucleic Acids Research 34, 4677-4684 2006

Bonvin M, F Achermann, I Greeve, D Stroka, A Keogh, D Inderbitzin, D Candinas,
P Sommer, S Wain-Hobson, JP Vartanian and J Greeve
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication
Hepatology 43, 1364-1374 2006

Centlivre M, P Sommer, M Michel, R Ho Tsong Fang, S Gofflo, J Valladeau, N Schmitt,
S Wain-Hobson and M Sala
HIV-1 C clade promoter is particularly well adapted to replication in the gut in primary infection
AIDS 20, 657-666 2006

Wain-Hobson S
The third Bond
Nature 439, 397 2006

Delebecque F, R Suspène, S Calattini, N Casartelli, A Saib, A Froment, S Wain-Hobson,
A Froment, A Gessain, JP Vartanian and O Schwartz
Restriction of foamy viruses by APOBEC cytidine deaminases
Journal of Virology 80, 605-614 2006

Dumaurier MJ, S Gratton, S Wain-Hobson and R Cheynier
The majority of human immunodeficiency virus type 1 particles present within splenic germinal centers are locally produced
Journal of General Virology 86, 3369-3373 2005

Bocharov G, NJ Ford, J Edwards, T Heintel, S Wain-Hobson and A Meyerhans
A genetic algorithm approach to simulating HIV evolution reveals the strong impact of multiply infected cells and recombination
Journal of General Virology 86, 3109-3018 2005

Renoux C, S Wain-Hobson, B Hurtrel and R Cheynier
Antigenic stimulation specifically reactivates the replication of archived SIV genomes in chronically infected macaques
Journal of Virology 79, 11231-11238 2005

Mahieux R, R Suspène, F Delebecque, M Henry, O Schwartz, S Wain-Hobson and
JP Vartanian
Extensive editing of human T cell leukaemia virus type 1 DNA by four APOBEC3 cytidine deaminases
Journal of General Virology 86, 2489-2494 2005

Suspène R, D Guétard, M Henry, P Sommer, S Wain-Hobson and JP Vartanian
Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo
Proceedings of the National Academy of Sciences USA 102, 8321-8326 2005

Centlivre M, P Sommer, M Michel, R Ho Tsong Fang, S Gofflo, J Valladeau, N Schmitt,
F Thierry, B Hurtrel, S Wain-Hobson and M Sala
HIV-1 clade promoters on an isogenic SIV background strongly influence the spatial and temporal dynamics of viral replication in vivo
Journal of Clinical Investigation, 115, 348-358 2005

Pineau P, M Henry, R Suspène, A Marchio, A Dettai, R Debruyne, T Petit, A Lecu, P Moisson, A Dejean, S Wain-Hobson and JP VartanianA universal primer set for PCR amplification of nuclear histone H4 genes from all animal species
Journal of Molecular Evolution, 22, 582-588 2005

Suspène R, M Henry, S Wain-Hobson & JP Vartanian
Recovery of APOBEC3-edited human immunodeficiency virus G->A hypermutants by differential DNA denaturation PCR
Journal of General Virology, 86, 125-129 2005

Wain-Hobson S and JP Vartanian
Editing HBV into oblivion
Hepatology, 40, 1461-1464 2004

Sommer P, JP Vartanian, M Wachsmuth, M Henry, D Guétard & S Wain-Hobson
Anti-termination by SIV Tat requires flexibility of the nascent TAR structure
Journal of Molecular Biology, 344, 11-28, 2004

Meyerhans A, T Heintel, JP Vartanian and S Wain-Hobson
Forms and function of intracellular HIV DNA
Los Alamos data base reviews on HIV, 14-21 2004

Leh-Louis V, B Wirth, L Despons, S Wain-Hobson, S Potier and J-L Souciet
Differential evolution of the Saccharomyces cerevisae DUP240 paralogs and implication of recombination in phylogeny
Nucleic Acids Research, 32, 2069-2078, 2004

Suspène R, P Sommer, M Henry, S Ferris, D Guétard, S Pochet, A Chester, N Navaratnam, S Wain-Hobson and JP Vartanian
APOBEC3G is a single stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase
Nucleic Acids Research, 32, 1-9, 2004