Unité de Virologie Structurale

Publications 20142013 / 2012 / 2011 / 2010 / 2009 / 2008 / 2007 / 2006 / 2005-1991


Robust and low cost uniform 15N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.
Meola A, Deville C, Jeffers SA, Guardado-Calvo P, Vasiliauskaite I, Sizun C, Girard-Blanc C, Malosse C, van Heijenoort C, Chamot-Rooke J, Krey T, Guittet E, Pêtres S, Rey FA, Bontems F.
J Struct Biol. 2014 Aug 28.

The highly conserved proline at position 438 in Pseudorabies Virus gH is important for regulation of membrane fusion.
Schröter C, Klupp BG, Fuchs W, Gerhard M, Backovic M, Rey FA, Mettenleiter TC.
J Virol. 2014 Sep 3.

Structural basis of eukaryotic cell-cell fusion.
Perez-Vargas J, Krey T, Valansi C, Avinoam O, Haouz A, Jamin M, Raveh-Barak H, Podbilewicz B, Rey FA.
Cell. 2014 Apr 10;157(2):407-19.


T helper type 2 bias and type 17 suppression in primary dengue virus infection in infants and young children.
Talarico LB, Bugna J, Wimmenauer V, Espinoza MA, Quipildor MO, Hijano DR, Beccaria M, Wurster V, Cavagnaro LE, Martinez D, Fattore G, Batalle JP, Acosta PL, Reynoso N, Melendi GA, Rey FA, Libster R, Polack FP.
Trans R Soc Trop Med Hyg. 2013 Jul;107(7):411-419.

Dengue virus: two hosts, two structures.
Rey FA.
Nature. 2013 May 23;497(7450):443-444.

Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Krey T, Meola A, Keck ZY, Damier-Piolle L, Foung SK, Rey FA.
PLoS Pathog. 2013 May;9(5):e1003364.

Structure of the Triatoma virus capsid.
Squires G, Pous J, Agirre J, Rozas-Dennis GS, Costabel MD, Marti GA, Navaza J, Bressanelli S, Guérin DM, Rey FA.
Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1026-1037.

The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.
Bakker SE, Duquerroy S, Galloux M, Loney C, Conner E, Eléouët JF, Rey FA, Bhella D.
J Gen Virol. 2013 Aug;94(Pt8):1734-1738.

Macromolecular assemblies.
Rey FA, Sundquist WI.
Curr Opin Struct Biol. 2013 Apr;23(2):224-228.

Alphavirus structure: activation for entry at the target cell surface.
Vaney MC, Duquerroy S, Rey FA.
Curr Opin Virol. 2013 Apr;3(2):151-158.

Editorial overview: Virus structure and function.
Marcotrigiano J, Rey FA.
Curr Opin Virol. 2013 Apr;3(2):101-102.

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission.
Tarr AW, Lafaye P, Meredith L, Damier-Piolle L, Urbanowicz RA, Meola A, Jestin JL, Brown RJ, McKeating JA,
Rey FA
, Ball JK, Krey T.
Hepatology. 2013 Mar 28.

Functional and evolutionary insight from the crystal structure of rubella virus protein.
Dubois RM, Vaney MC, Tortorici A, Al Kurdi R, Barba-Spaeth G, Krey T, Rey FA.
Nature 2013. Jan 24;493(7433):552-556.


SnapShot: Viral and Eukaryotic Protein Fusogens.
Igonet S., Rey FA.
Cell 2012. Dec 21;151(7):1634-1634.

Characterization of a viral phosphoprotein binding site on the surface of the respiratory syncitial nucleoprotein.
Galloux M, Tarus B, Blazevic I, Fix J, Duquerroy S, Eléouët JF.
J Virol. 2012 Aug;86(16):8375-8387.

Structure-based mutational analysis of the highly conserved domain IV of glycoprotein H of pseudorabies virus.
Fuchs W, Backovic M, Klupp BG, Rey FA, Mettenleiter TC.
J Virol. 2012 Aug;86(15):8002-8013.

Crystal structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Krey T, Bontems F, Vonrhein C, Vaney MC, Bricogne G, Rümenapf T, Rey FA.
Structure. 2012 May 9;20(5):862-873.

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV e2 with resistance to neutralization escape in a genotype 2a isolate.
Keck ZY, Xia J, Wang Y, Wang W, Krey T, Prentoe J, Carlsen T, Li AY, Patel AH, Lemon SM, Bukh J, Rey FA, Foung SK.
PLoS pathogens. 2012 Apr;8(4):e1002653.

Virus entry: old viruses, new receptors.
Backovic M, Rey FA.
Curr Opin Virol. 2012 Feb; 2(1):4-13.

Mechanism of Dengue Virus Broad Cross-Neutralization by a Monoclonal Antibody.
Cockburn JJ, Navarro Sanchez ME, Fretes N, Urvoas A, Staropoli I, Kikuti CM, Coffey LL, Arenzana Seisdedos F, Bedouelle H, Rey FA.
Structure. 2012 Feb 8;20(2):303-314.

The crystal structure of Human alpha(2)-Macroglobulin reveals a unique molecular cage.
Marrero A, Duqueroy S, Trapani S, Goulas T, Guevara T, Andersen GR, Navaza J, Sottrup-Jensen L, Gomis-Rüth FX.
Angew Chem Int Ed Engl. 2012 April 2;51(14):3340-3344.

High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies (scFv) from Drosophila S2 cells.
Gilmartin AA, Lamp B, Ruemenapf T, Persson MA, Rey FA, Krey T.
Protein Eng Des Sel. 2012 Feb;25(2):59-66.

Structural insight into the neutralization mechanism of a higher primate antibody against dengue virus.
Cockburn J, Navarro-Sanchez E, Goncalvez A, Zaitseva E, Stura EA, Kikuti CM, Duquerroy S, Chernomordik L, Lai CJ, Dussart P, Rey FA.
EMBO J. 2012 Feb 1;31(3):767-779.


X-ray structure of the arenavirus glycoprotein GP2 in its postfusion conformation.
Igonet S, Vaney MC, Vonrhein C, Bricogne G, Stura EA, Hengartner H, Eschli B, Rey FA.
Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):19967-19972.

Potential role of invariant NKT cells in the control of pulmonary inflammation and CD8+ T cell response during acute influenza A virus H3N2 pneumonia.
Paget C, Ivanov S, Fontaine J, Blanc F, Pichavant M, Renneson J, Bialecki E, Pothlichet J, Vendeville C, Barba-Spaeth G, Huerre MR, Faveeuw C, Si-Tahar M, Trottein F. 
J Immunol. 2011 186(10): 5590-5602.

Peptides targeting the PDZ domain pf PTPN4 are efficient inducers of glioblastoma cell death.
Babault N, Cordier F, Lafage M, Cockburn J, Haouz A, Prehaud C, Rey FA, Delepierre M, Buc H, Lafin M, Wolff N.
Structure. 2011 Oct 12;19(10):1518-1524.

Characterisation of a DNA polymerase highly mutated along the template binding interface.
Vichier-Guerre S, Jestin JL.
Mol Biotechnol. 2011 46(1):58-62.

Virus/host interactions: a strong force driving the diversification of cellular organisms.
Rey FA.
Curr Opin Microbiol. 2011 Aug;14(4):445-448.

Mapping a region of HCV E2 that is responsible for escape from neutralizing antibodies and a core CD81-binding region that does not tolerate neutralization escape mutations.
Keck ZY, Saha A, Xia J, Wang Y, Lau P, Krey T, Rey FA, Foung SK.
J Virol. 2011 Oct;85(20):10451-10463.

Class II enveloped viruses.
Vaney MC, Rey FA.
Cell Microbiol. 2011 Oct;13(10):1451-1459. Review.

Class III viral membrane fusion proteins.
Backovic M, Jardetzky TS.
Adv Exp Med Biol. 2011 714:91-101. Review.

Picobirnaviruses encode a protein with repeats of the ExxRxNxxxE motif.
Da Costa B, Duquerroy S, Tarus B, Delmas B.
Virus Res. 2011 Jun;158(1-2):251-256.

Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein.
Gutsche I, Coulibaly F, Voss JE, Salmon J, d'Alayer J, Ermonval M, Larquet E, Charneau P, Krey T, Mégret F, Guittet E, Rey FA, Flamand M.
Proc Natl Acad Sci U S A. 2011 May 10;108(19):8003-8008.

Macromolecular assemblages.
Rey FA, Sundquist WI.
Curr Opin Struct Biol. 2011 Apr;21(2):221-222.

Capsid protein identification and analysis of mature Triatoma virus (TrV) virions and naturally occurring empty particles.
Agirre J, Aloria K, Arizmendi JM, Iloro I, Elortza F, Sánchez-Eugenia R, Marti GA, Neumann E, Rey FA, Guérin DM.
Virology. 2011 Jan 5;409(1):91-101.


Virologie: One protein, many functions.
Rey FA.
Nature. 2010 Dec 9;468(7325):773-775. News and Views.

Structure of a core fragment of glycoprotein H from Pseudorabies virus in complex with antibody.
Backovic M, Dubois R, Cockburn JJ, Sharff AJ, Vaney MC, Granzow H, Klupp BG, Bricogne G, Mettenleiter TC, Rey FA.
Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22635-22640.

Glycoprotein organization of chikungunya virus particles revealed by X-ray crystallography.
Voss JE, Vaney M-C, Duquerroy S, Vonrhein C, Girard-Blanc C, Crublet E, Thompson A, Bricogne G, Rey FA.
Nature. 2010 Dec 2;468:709-712.
News and Views. Structural biology: An alphavirus puzzle solved. By Margaret Kielian.
Nature. 2010 Dec 2;468:645-646.

Identification of new functional regions in hepatitis C virus envelope glycoprotein E2.
Albecka A, Monserret R, Krey T, Tarr AW, Diesis E, Ball JK, Descamps V, Duverlie G, Rey F, Penin F, Dubuisson J.
J Virol. 2010 Feb;85(4):1777-1792.

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity.
Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, Quyen NT, Sukupolvi-Petty S, Navarro-Sanchez E, Young PR, de Silva AM, Rey FA, Varani L, Whitehead SS, Diamond MS, Harris E, Lanzavecchia A, Sallusto F.
Cell Host Microbe. 2010 Sep 16;8(3):271-283.

Further insights into the roles of GTP and the C-terminus of the Hepatitis C virus polymerase in the initiation of RNA synthesis.
Harrus D, Ahmed-El-Sayed N, Simister PC, Miller S, Triconnet M, Hagedorn CH, Mahias K, Rey FA, Astier-Gin T, Bressanelli S.
J Biol Chem. 2010 Oct 22;285(43):32906-32918.

The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule.
Krey T, d’Alayer J, Kikuti CM, Saulnier A,Damier-Piolle L, Petitpas I, Johansson DX, Tawar RG, Baron B, Robert B, England P, Persson MA, Martin A, Rey FA.
PLoS Pathog. 2010 Feb 19;6(2):e1000762.

Efficient method for production of high yields of Fab fragments in Drosophila S2 cells.
Backovic M, Johansson DX, Klupp BG, Mettenleiter TC, Persson MA, Rey FA.
Protein Eng Des Sel. 2010 Apr;23(4):169-174.

Herpes simplex virus glycoproteins H/L bind to cells independently of {alpha}V{beta}3 integrin and inhibit virus entry, and their constitutive expression restricts infection.
Gianni T, Cerretani A, Dubois R, Salvioli S, Blystone SS, Rey FA, Campadelli-Fiume G.
J Virol 2010; 84(8): 4013-4025.

Crystal structure of an Aquabirnavirus particle: insights into antigenic diversity and virulence determinism.
Coulibaly F, Chevalier C, Delmas B, Rey FA.
J Virol. 2010 Feb;84(4):1792-1799.

Sequence-dependent DNA flexibility mediates DNase I cleavage.
Heddi B, Abi-Ghanem J, Lavigne M, Hartmann B.
J Mol Biol. 2010 Jan 8;395(1):123-133.

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.
Grubisha O, Kaminska M, Duquerroy S, Fontan E, Cordier F, Haouz A, Raynal B, Chiaravalli J, Delepierre M, Israël A, Véron M, Agou F.
J Mol Biol. 2010 Jan 8;395(1):89-104.

Expression and purification of  Z protein from Junín virus.
Goñi SE, Borio CS, Romano FB, Rota RP, Pilloff MG, Iserte JA, Tortorici MA, Stephan BI, Bilen MF, Ghiringhelli PD, Lozano ME.
J Biomed Biotechnol. 2010;2010:970491.

Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against Plasmodium yoelii.
Stoyanov CT, Boscardin SB, Deroubaix S, Barba-Spaeth G, Franco D, Nussenzweig RS, Nussenzweig M, Rice CM.
Vaccine. 2010;28:4644-4652.


Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus.
Tawar RG, Duquerroy S, Vonrhein C, Varela PF, Damier-Piolle L, Castagné N, MacLellan K, Bedouelle H, Bricogne G, Bhella D, Eléouët JF, Rey FA.
Science. 2009 Nov 27;326(5957):1279-1283.

Single-particle cryoEM reconstructions: meeting the challenge.
Rey FA.
Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10398-10399.

The picobirnavirus crystal structure provides functional insights into virion assembly and cell entry.
Duquerroy S, Da Costa B, Henry C, Vigouroux A, Libersou S, Lepault J, Navaza J, Delmas B, Rey FA.
EMBO J. 2009 Jun 3;28(11):1655-1665.

Macromolecular assemblies.
Rey FA, Saibil H.
Curr Opin Struct Biol. 2009 Apr;19(2):178-180.

Structure of the outer membrane complex of a type IV secretion system.
Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J, Waksman G.
Nature. 2009 Dec 24;462(7276):1011-1015.

La structure cristalline de la capside du picobirnavirus révèle une organisation géométrique originale.
Duquerroy S, Da Costa B, Henry C, Vigouroux A, Libersou S, Lepault J, Navaza J, Delmas B, Rey FA.
Virologie. 2009 13(4), 233-234.

Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression.
Lavigne M, Eskeland R, Azebi S, Saint-André V, Jang SM, Batsché E, Fan HY, Kingston RE, Imhof A, Muchardt C.
PLoS Genet. 2009 Dec;5(12):e1000769.


Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth.
Kwan WH, Navarro-Sanchez E, Dumortier H, Decossas M, Vachon H, dos Santos FB, Fridman HW, Rey FA, Harris E, Despres P, Mueller CG.
PLoS Negl Trop Dis. 2008 Oct 1;2(10):e311.

Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein.
Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, Kraüsslich HG.
J Biol Chem. 2008 Nov 14;283(46):32024-32033.

Phasing of the Triatoma virus diffraction data using a cryo-electron microscopy reconstruction.
Estrozi LF, Neumann E, Squires G, Rozas-Dennis G, Costabel M, Rey FA, Guérin DM, Navaza J.
Virology. 2008 May 25;375(1):85-93.

Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein.
Bosch BJ, Rossen JW, Bartelink W, Zuurveen SJ, de Haan CA, Duquerroy S, Boucher CA, Rottier PJ.
J Virol. 2008 Mar;82(5):2580-2585.

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.
Shun MC, Botbol Y, Li X, Di Nunzio F, Daigle JE, Yan N, Lieberman J, Lavigne M, Engelman A.
J Virol. 2008 Dec;82(23):11555-11567.

Chromatinized templates reveal the requirement for the LEDGF/p75 PWWP domain during HIV-1 integration in vitro.
Botbol Y, Raghavendra NK, Rahman S, Engelman A, Lavigne M.
Nucleic Acids Res. 2008 Mar;36(4):1237-1246.

Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del Carpio R, Nibert ML, Patton JT, Harrison SC.
Structure. 2008 Nov 12;16(11):1678-1688.


Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus.
Letzel T, Coulibaly F, Rey FA, Delmas B, Jagt E, van Loon AA, Mundt E.
J Virol. 2007 Dec;81(23):12827-35.

Characterization of reemerging chikungunya virus.
Sourisseau M, Schilte C, Casartelli N, Trouillet C, Guivel-Benhassine F, Rudnicka D, Sol-Foulon N, Le Roux K, Prevost MC, Fsihi H, Frenkiel MP, Blanchet F, Afonso PV, Ceccaldi PE, Ozden S, Gessain A, Schuffenecker I, Verhasselt B, Zamborlini A, Saïb A, Rey FA, Arenzana-Seisdedos F, Desprès P, Michault A, Albert ML, Schwartz O.
PLoS Pathog. 2007 Jun;3(6):e89.

Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation.
Duquerroy S, Stura EA, Bressanelli S, Fabiane SM, Vaney MC, Beale D, Hamon M, Casali P, Rey FA, Sutton BJ, Taussig MJ.
J Mol Biol. 2007 May 18;368(5):1321-31.

Virology: holed up in a natural crystal.
Rey FA.
Nature. 2007 Mar 1;446(7131):35-7. News and Views.

Characterization of a structural intermediate of flavivirus membrane fusion.
Stiasny K, Kössl C, Lepault J, Rey FA, Heinz FX.
PLoS Pathog. 2007 Feb;3(2):e20.

Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G.
Roche S, Rey FA, Gaudin Y, Bressanelli S.
Science. 2007 Feb 9;315(5813):843-8.

The nine C-terminal amino acids of the respiratory syncytial virus protein P are necessary and sufficient for binding to ribonucleoprotein complexes in which six ribonucleotides are contacted per N protein protomer.
Tran TL, Castagné N, Bhella D, Varela PF, Bernard J, Chilmonczyk S, Berkenkamp S, Benhamo V, Grznarova K, Grosclaude J, Nespoulos C, Rey FA, Eléouët JF.
J Gen Virol. 2007 Jan;88(Pt 1):196-206.

Structural rearrangements between portal protein subunits are essential for viral DNA translocation.
Cuervo A, Vaney MC, Antson AA, Tavares P, Oliveira L.
J Biol Chem. 2007 Jun 29;282(26):18907-13.

Coupling of rotavirus genome replication and capsid assembly.
Patton JT, Vasquez-Del Carpio R, Tortorici MA, Taraporewala ZF.
Adv Virus Res. 2007;69:167-201. Review.


Molecular gymnastics at the herpesvirus surface.
Rey FA.
EMBO Rep. 2006 Oct;7(10):1000-5. Review.

Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein.
Roche S, Bressanelli S, Rey FA, Gaudin Y.
Science. 2006 Jul 14;313(5784):187-91. Erratum in: Science. 2006 Sep 8;313(5792):1389.

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak.
Schuffenecker I, Iteman I, Michault A, Murri S, Frangeul L, Vaney MC, Lavenir R, Pardigon N, Reynes JM, Pettinelli F, Biscornet L, Diancourt L, Michel S, Duquerroy S, Guigon G, Frenkiel MP, Bréhin AC, Cubito N, Desprès P, Kunst F, Rey FA, Zeller H, Brisse S.
PLoS Med. 2006 Jul;3(7):e263.

Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virus.
Roussel A, Lescar J, Vaney MC, Wengler G, Wengler G, Rey FA.
Structure. 2006 Jan;14(1):75-86.

Virus membrane-fusion proteins: more than one way to make a hairpin.
Kielian M, Rey FA.
Nat Rev Microbiol. 2006 Jan;4(1):67-76. Review.

Les relations structurales entre birnavirus et autres virus icosaédriques à ARN.
Coulibaly F, Chevalier C, Galloux M, Da Costa B, Lepault J, Delmas B, Rey F.
Virologie. 2006 10(3), 233-5.

Rotavirus genome replication and morphogenesis: role of the viroplasm.
Patton JT, Silvestri LS, Tortorici MA, Vasquez-Del Carpio R, Taraporewala ZF.
Curr Top Microbiol Immunol. 2006;309:169-87. Review

A base-specific recognition signal in the 5’ consensus sequence of rotavirus plus-strand RNAs promotes replication of the double-stranded RNA genome segments.
Tortorici MA, Shapiro BA, Patton JT.
RNA. 2006 Jan;12(1):133-46.

Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics.
Marcello T, Grakoui A, Barba-Spaeth G, Machlin ES, Kotenko SV, MacDonald MR, Rice CM.
Gastroenterology. 2006 Dec;131(6):1887-98.



Crystal structure of a pivotal domain of human syncytin-2, a 40 million years old endogenous retrovirus fusogenic envelope gene captured by primates. Renard M, Varela PF, Letzelter C, Duquerroy S, Rey FA, Heidmann T. J Mol Biol 352:1029-1034. (2005)

The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor. Ternois F, Sticht J, Duquerroy S, Krausslich HG, Rey FA. Nat Struct Mol Biol. 2005 12:678-682. (2005)

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals. Lozach PY, Burleigh L, Staropoli I, Navarro-Sanchez E, Harriague J, Virelizier JL, Rey FA, Despres P, Arenzana-Seisdedos F, Amara A. J Biol Chem. 280: 23698-23708. (2005)

The birnavirus crystal structure reveals new structural relationships among icosahedral viruses. Coulibaly F, Chevalier C, Gutsche I, Pous J, Navaza J, Bressanelli S, Delmas B, Rey, FA. Cell 120:761-772. (2005)

Central ions and lateral asparagine/glutamine zippers stabilize the post -fusion hairpin conformation of the SARS coronavirus spike glycoprotein. Duquerroy S, Bressanelli S, Rottier PJM, Rey FA and Bosch BJ. Virology 335:276-285. (2005)

Cryomicroscopie électronique/radiocristallographie : une approche permettant d’accéder aux mécanismes biologiques à la résolution atomique.
J Lepault, J Navaza, F Rey. Virologie 9(5), 409-11. (2005)


Purification, crystallization and preliminary X-ray analysis of Triatoma Virus (TrV) from Triatoma infestans. Rozas-Dennis G, Squires G, Pous J, Costabel MD, Lepault J, Navaza J, Rey, FA., Guerin DMA. Acta Cryst. D60,1647-1650. (2004)

Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus. Gibbons DL, Vaney MC, Roussel A, Vigouroux A, Reilly B, Lepault J, Kielian M, Rey FA. Nature 427, 320-325. (2004)

Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation. Bressanelli S, Stiasny K, Allison SL, Stura EA, Duquerroy S, Heinz FX, Rey FA. EMBO J. 23:728-738. (2004)

Characterization of a membrane-associated trimeric form of the class II viral fusion protein E from tick-borne encephalitis. Stiasny K, Bressanelli S, Lepault J, Rey FA, Heinz FX. J. Virol. 78:3178-3183. (2004)

Purification and crystallization reveal two types of interactions of the fusion protein homotrimer of Semliki Forest virus. Gibbons DL, Reilly B, Ahn A, Vaney MC, Vigouroux A, Rey FA,  Kielian M. J. Virol. 78:3514-3523. (2004)

Structural Biology of Hepatitis C Virus. Penin F, Dubuisson J, Rey FA, Moradpour D, Pawlotsky JM. Hepatology 39: 1-19. (2004)

Propagation of silencing; recruitment and repression of naive chromatin in trans by polycomb repressed chromatin. Lavigne M, Francis NJ, King IF, Kingston RE. Mol Cell. Feb 13;13(3):415-25. (2004)


Visualization of the target-membrane-inserted fusion protein of Semliki Forest virus by combined electron microscopy and crystallography. Gibbons DL, Erk I, Reilly B, Navaza J, Kielian M, Rey FA, Lepault J. Cell 114: 573-583. (2003)

Dengue virus envelope glycoprotein structure: New insights into its interactions during viral entry. Rey FA. (Comment) Proc Natl Acad Sci U S A, 100, 6899-6901. (2003)

A zinc ion controls assembly and stability of the major capsid protein of rotavirus. Erk I, Huet JC, Duarte M, Duquerroy S, Rey F, Cohen J, Lepault J. J. Virol 77: 3595-3601. (2003)

The three-dimensional structure of rotavirus VP6. Rey FA, Lepault J, Cohen J. In "Viral Gastroenteritis", U. Desselberger and J. Gray, Editors. Perspectives in Medical Virology Series, Vol 9. (Zuckerman and Mushahwar, Series editors) ISBN 0 444 51444 9. Elsevier, Amsterdam. Pages 129-142. (2003)


Genome analysis of dengue type-1 virus isolated between 1990 and 2001 in Brazil reveals a remarkable conservation of the structural proteins but amino acid differences in the non-structural proteins. Dos Santos CN, Rocha CF, Cordeiro M, Fragoso S, Rey F, Deubel V, Despres P. Virus Res. 90:197-205. (2002)

Scaffolds for protein crystallisation. Stura EA, Taussig MJ, Sutton BJ, Duquerroy S, Bressanelli S, Minson AC, Rey FA. Acta Cryst. D58:1715-1721. (2002)

On the fitting of model electron densities into EM reconstructions: a reciprocal-space formulation. Navaza J, Lepault J, Rey FA, Alvarez-Rua C, Borge J. Acta Cryst. D58:1820-1825. (2002)

Identification of rotavirus VP6 residues located at the interface with VP2 that are essential for capsid assembly and transcriptase activity. Charpilienne A, Lepault J, Rey F, Cohen J. J. Virol. 76:7822-7831. (2002)

Structural analysis of the hepatitis C virus RNA polymerase in complex with ribonucleotides. Bressanelli S, Tomei L, Rey FA, De Francesco R. J Virol. 76:3482-3492. (2002)


The Fusion Glycoprotein Shell of Semliki Forest Virus. An Icosahedral Assembly Primed for Fusogenic Activation at Endosomal pH. Lescar J, Roussel A, Wien MW, Navaza J, Fuller SD, Wengler G, Rey FA. Cell, 105, 137-148. (2001)

Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion. Mathieu M, Petitpas I, Navaza J, Lepault J, Kohli E, Pothier P, Prasad BV, Cohen J, Rey F. A. EMBO J, 20, 1485-1497. (2001)

Structural polymorphism of the major capsid protein of rotavirus. Lepault J, Petitpas I, Erk I, Navaza J, Bigot D, Dona M, Vachette P, Cohen J, Rey FA. EMBO J, 20, 1498-1507. (2001)

Molecular Organization of a Recombinant Subviral Particle from Tick-Borne Encephalitis Virus. Ferlenghi I, Clarke M, Ruttan T, Allison SL, Schalich J, Heinz FX, Harrison SC, Rey FA, Fuller SD. Molecular Cell. 7, 593-602. (2001)

Antibody inhibition of the transcriptase activity of the rotavirus DLP: a structural view. Thouvenin E, Schoehn G, Rey F, Petitpas I, Mathieu M, Vaney MC, Cohen J, Kohli E, Pothier P, Hewat E. J. Mol Biol. 307, 161-72. (2001)


Determinants in the envelope E protein and viral RNA helicase NS3 that influence the induction of apoptosis in response to infection with dengue type 1 virus. Duarte dos Santos CN, Frenkiel MP, Courageot MP, Rocha CF, Vazeille-Falcoz MC, Wien MW, Rey FA, Deubel V, Despres P. Virology, 274, 292-308. (2000)


Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Bressanelli S, Tomei L, Roussel A, Incitti I, Vitale RL, Mathieu M, De Francesco R, Rey FA. Proc Natl Acad Sci U S A, 96, 13034-9. (1999)

Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion. Flamand M, Megret F, Mathieu M, Lepault J, Rey FA, Deubel V. J Virol. 73, 6104-10. (1999)

The isolation of the ectodomain of the alphavirus E1 glycoprotein as a soluble hemagglutinin and its crystallization. Wengler G, Wengler G, Rey FA. Virology 257 : 472-482. (1999)

A dimer of trimers of Rotavirus protein VP6 as a possible intermediate in the assembly of the viral particle. Rey FA. CR Acad. Agr. Fr. 85 19-21. (1999)


Crystallization and preliminary X-ray analysis of rotavirus protein VP6. Petitpas I, Lepault J, Vachette P, Charpilienne A, Mathieu M, Kohli E, Pothier P, Cohen J, Rey FA. J. Virol. 72 :7615-7619. (1998)

Comparison of two different DNA-binding modes of the NF-kappa B p50 homodimer. Muller CW, Rey FA, Harrison SC. Nature Structural Biology. 3:224-227. (1996)

The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Rey FA, Heinz FX, Mandl C, Kunz C, Harrison SC. Nature. 375:291-298. (1995)

Structure of the NF-kappa B p50 homodimer bound to DNA. Muller CW, Rey FA, Sodeoka M, Verdine GL, Harrison SC. Nature. 373:311-317. (1995)

Protein Engineering of Xylose (glucose) Isomerase from Actinoplanes Missouriensis. 1. Crystallography and Site-Directed Mutagenesis of Metal Binding Sites. Jenkins J, Janin J, Rey FA, Chiadmi M, Van Tilbeurg H, Lasters I, De Maeyer M, Van Belle D, Wodak SJ, Lauwereys M, Stanssens P, Mrabet NT, Snauwaert J, Matthyssens G, Lambeir AM. Biochemistry. 31, 5449-5458. (1992)

Arginines as Stabilizing Elements in Proteins. Mrabet NT, Van den Broeck A,Van den Brande I, Stanssens P, Laroche Y, Lambeir AM, Matthyssens G, Jenkins J, Chiadmi M, Van Tilbeurg H, Rey FA, Janin J, Quax WH, Lasters I, De Maeyer M, Wodak SJ. Biochemistry 31, 2239-2253. (1992)

The Flavivirus Envelope Protein E: Isolation of a Soluble Dimeric Form From Tick Borne Encephalitis Virus and its Crystallization. Heinz FX, Mandl,CW, Holtzmann H, Kunz C, Harris BA, Rey FA, Harrison SC. J. Virol. 65, 5579-5583. (1991)

FFT method to compute solution X-ray scattering curves. Rey FA, Dumas C. Biochimie. 66:121-126. (1984)