Structural Microbiology / Publications / Publications 2013

Publications 2013


Non-quinolone Inhibitors of Bacterial Type IIA Topoisomerases: A Feat of Bioisosterism.

Mayer C, Janin YL.Chem Rev. 2013 Dec 6. 


Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion.

Agrawal A, Roué M, Spitzfaden C, Petrella S, Aubry A, Hann M, Bax B, Mayer C.Biochem J. 2013 Dec 1


Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes.

Bouige A, Darmon A, Piton J, Roue M, Petrella S, Capton E, Forterre P, Aubry A, Mayer C.Biochem J. 2013 Nov 1

Structure-Function Relationships of Membrane Associated GT-B Glycosyltransferases.

Albesa-Jové D, Giganti D, Jackson M, Alzari PM, Guerin ME.
Glycobiology. 2013 Nov 18.


A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial α-ketoglutarate decarboxylase (KGD).

Wagner T, Barilone N, Alzari PM, Bellinzoni M.
Biochem J
. 2013 Oct 31.


GarA is an essential regulator of metabolism in Mycobacterium tuberculosis.

Ventura M, Rieck B, Boldrin F, Degiacomi G, Bellinzoni M, Barilone N, Alzaidi F, Alzari PM, Manganelli R, O'Hare HM.
Mol Microbiol. 2013 Oct 
 

Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center.

Gil M, Graña M, Schopfer FJ, Wagner T, Denicola A, Freeman BA, Alzari PM, Batthyány C, Durán R.
Free Radic Biol Med. 2013 Dec;65:150-61. doi: 10.1016/j.freeradbiomed.2013.06.021. Epub 2013 Jun 20.
 

Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain.

Roué M, Agrawal A, Volker C, Mossakowska D, Mayer C, Bax BD.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun

Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins.

Béhar G, Bellinzoni M, Maillasson M, Paillard-Laurance L, Alzari PM, He X, Mouratou B, Pecorari F.
Protein Eng Des Sel
. 2013 Apr;26(4):267-75.
 

Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus.

Albanesi D, Reh G, Guerin ME, Schaeffer F, Debarbouille M, Buschiazzo A, Schujman GE, de Mendoza D, Alzari PM.
PLoS Pathog
. 2013 Jan;9(1):e1003108.