Publications 2009

Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria.

Graña M, Bellinzoni M, Miras I, Fiez-Vandal C, Haouz A, Shepard W, Buschiazzo A, Alzari PM.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt 10):972-7. 


Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator.
Bellinzoni M
, Buroni S, Schaeffer F, Riccardi G, De Rossi E, Alzari PM.
J Bacteriol
. 2009 Dec;191(24):7531-7. 


Structural plasticity and catalysis regulation of a thermosensor histidine kinase.

Albanesi D, Martín M, Trajtenberg F, Mansilla MC, Haouz A, Alzari PM, de Mendoza D, Buschiazzo A.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16185-90. 

Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1.

Hindie V, Stroba A, Zhang H, Lopez-Garcia LA, Idrissova L, Zeuzem S, Hirschberg D, Schaeffer F, Jørgensen TJ, Engel M, Alzari PM, Biondi RM.

Nat Chem Biol. 2009 Oct;5(10):758-64.

Mechanisms determining cell membrane expression of different gammadelta TCR chain pairings.

Boucontet L, Grana M, Alzari PM, Pereira P.

Eur J Immunol. 2009 Jul;39(7):1937-46.

Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis.

Guerin ME, Schaeffer F, Chaffotte A, Gest P, Giganti D, Korduláková J, van der Woerd M, Jackson M, Alzari PM.

J Biol Chem. 2009 Aug 7;284(32):21613-25. 

Bacterial metabolism under FHA control.

Bellinzoni M, Alzari PM.

Structure. 2009 Apr 15;17(4):487-8.  

Functional in vitro assembly of the integral membrane bacterial thermosensor DesK.

Martín M, Albanesi D, Alzari PM, de Mendoza D.

Protein Expr Purif. 2009 Jul;66(1):39-45. 


Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis.

Sala C, Haouz A, Saul FA, Miras I, Rosenkrands I, Alzari PM, Cole ST.

Mol Microbiol. 2009 Mar;71(5):1102-16. 

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening.

Neres J, Brewer ML, Ratier L, Botti H, Buschiazzo A, Edwards PN, Mortenson PN, Charlton MH, Alzari PM, Frasch AC, Bryce RA, Douglas KT.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):589-96.

The FHA-containing protein GarA acts as a phosphorylation-dependent molecular switch in mycobacterial signaling.

England P, Wehenkel A, Martins S, Hoos S, André-Leroux G, Villarino A, Alzari PM.

FEBS Lett. 2009 Jan 22;583(2):301-7.