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Chemistry and Biocatalysis - Sylvie POCHET
Activities of the Unit
Research deals with the design and synthesis of molecules that interfere with nucleoside metabolism enzymes, and the characterization of unexplored targets. Enzymatic approaches are developed as an alternative to chemical routes. The main goal is the identification of inhibitors (by rational drug design, fragment based approach, screening of chemical libraries) of essential bacterial or mammalian enzymes as anti-infectious and anti-tumoral agents. The research aims to the validation of target enzymes and the identification of new therapeutic agents.
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Screening platform
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Web site of the Unit
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