Chemistry and Biocatalysis - Sylvie POCHET

Activities of the Unit

Research deals with the design and synthesis of molecules that interfere with nucleoside metabolism enzymes, and the characterization of unexplored targets. Enzymatic approaches are developed as an alternative to chemical routes. The main goal is the identification of inhibitors (by rational drug design, fragment based approach, screening of chemical libraries) of essential bacterial or mammalian enzymes as anti-infectious and anti-tumoral agents. The research aims to the validation of target enzymes and the identification of new therapeutic agents.


Screening platform

Web site of the Unit