Research / Scientific departments / Structural Biology and Chemistry / Units and Groups / Biophysics of Macromolecules and their interactions
Biophysique des macromolécules et de leurs interactions
Size and shape of macromolecules
Relevant technologies at the PFBMI
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Dynamic light scattering (DLS)
Quantification of diffusion rate and, by deduction of hydrodynamic radius (a value that depends on their mass and shape, notably) |
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Static light scattering and viscometry
Measure of mass and intrinsic viscometry of macromolecules Oligomerisation state and stœchiometry of assemblies |
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Analytical Ultracentrifugation
Measurement of mass and shape of macromolecules in solution. Oligomerisation state, stœchiometry, equilibrium constant of assemblies |
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The PFBMI can advise you or direct you on your choices and give you information on:
* Experiments requirements and constraints
* Lenght if experiments
* Estimations and calculations of physico-chemical parameters
* Methodological links and softwares to be used
* Experiments requirements and constraints
* Lenght if experiments
* Estimations and calculations of physico-chemical parameters
* Methodological links and softwares to be used