Research / Scientific departments / Structural Biology and Chemistry

Department of Structural Biology and Chemistry


 
Prof. Michael NILGES
Chairman of the Department
Tél. : 33 (0)1 45 68 82 30
Email: michael.nilges@pasteur.fr
Dr Daniel LADANT
Co-chairman of the Department
Tél. : 33 (0)1 45 68 84 00
Email: daniel.ladant@pasteur.fr



Secretary : Mme Catherine TRAN
email : catherine.tran@pasteur.fr

Activities of the Department

The researchers, engineers, students and post-docs of the Department of Structural Biology and Chemistry use an integrative approach to the study of complex biological systems. Through observation and experiments with the latest technological tools, we study the fine detail of molecular mechanisms and the structure of molecules at multiple resolutions. The department includes a strong structural biology component, which resorts principally to X-ray diffraction, NMR and cryo-electron microscopy. The chemistry component focuses notably on saccharides and nucleic acids. Several teams also study molecular interactions and reactions, and their physiological impact at the cellular level of the cell, using a variety of biochemical, biophysical and microscopy methods. Simulation and in silico prediction completes the ensemble of approaches that are used in the Department. Our research benefits largely from the cutting-edge equipment federated within technological core facilities.

The Department is composed of two UMR CNRS : 
UMR 3528 "Structural Biology of Cellular processes and Infectious Diseases , and UMR 3523 « Organic Chemistry Unit ».