Publications
1.Späth G.F., McDowell M.A., and S.M. Beverley SM, “Leishmania major intracellular survival is not altered in SHP-1 deficient me(v) or CD45(-/-) mice”, Exp Parasitol. 2008 Jul 19[Epub ahead print]
2.Morales M.A., Watanabe R., Laurent C., Lenormand P., Rousselle J.C., Namane A. and G.F. Späth, “Phosphoproteomic analysis of Leishmania donovani pro- and amastigote stages”, Proteomics, 2008 18:350-363.
3.Frevert U., Späth G.F. and H. Yee, “Exoerythrocytic development of Plasmodium gallinaceum in the White Leghorn chicken”. Int J Parasitology, 2008, 38:655-72.
4.Morales M.A., Renaud O., Faigle W., Shorte S.L. and G. F. Späth, “ Over-expression of Leishmania major MAP kinases reveals stage-specific induction of phosphotransferase activity”, Int. J. of Parasitology, 2007, 11:1187-99.
5.Arevalo I, Tulliano G, Quispe A, Spaeth G, Matlashewski G, Llanos-Cuentas A, Pollack H, “Role of imiquimod and parenteral meglumine antimoniate in the initial treatment of cutaneous leishmaniasis”, 2007, Clin. Infect. Dis., 2007 44:1549-54.
6.Boulanger, N., C. Lowenberger, P. Volf, R. Ursic, L. Sigutova, L. Sabatier, M. Svobodova, R. Brun, G. Späth, S.M. Beverley, S. Perrotey, B. Pesson, and P. Bulet (2004), “Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major” , Infection & Immunity, 2004 72: 7140.
7.Soos T.J., Marsland, B.J. Späth G.F, Kopf M., and D. Littman, “Impaired Th2 cell differentiation in the absence of PKCtheta”, J. Exp. Med. 2004 200:181.
8.Amprey J.L., Im J.S., Turco S.J., Murray H.W., Illarionov P.A., Besra G.S., Porcelli S.A., and G. F. Späth, “Innate recognition of Leishmania donovani glycolipids by CD1d-restricted T cells induces an early protective immune response during liver infection”, J. Exp. Med 2004, 200:895.
9.Amprey J., Späth G.F., and S. Porcelli, “Inhibition of CD1 expression in human dendritic cells during intracellular infection with Leishmania donovani”, Infection & Immunity, 2004 72:589.
10.Uzonna J., Späth G.F., Beverley S.M., and P. Scott, “ Vaccination with phosphoglycan-deficient lpg2- knock-out Leishmania major protects highly susceptible mice from virulent challenge”, J. Immunol., 2004 172:3793.
11.Späth G.F., Lye L.F. and S.M. Beverley, “Identification of a compensatory mutant (lpg2-REV) in Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates, and its significance to virulence and immunization strategies”, Infection & Immunity, 2004 72:3622.
12.Späth G.F., Lye, L.F., Segawa, H., Sacks, D., Turco S.J.and S.M. Beverley, " Persistence without Pathology in Phosphoglycan-Deficient Leishmania major”, Science, 2003 29:124.
13.Späth G.F., Garraway, L., Turco S.J.and S.M. Beverley, “The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts”, Proc. Natl. Acad. Sci. U S A, 2003 100:9536.
14.Salvatore J. Turco, Gerald Späth, and Stephen M. Beverley, " Is Lipophosphoglycan a Virulence Factor? A surprising diversity between Leishmania species", Trends in Parasitology, 2001 17:223-6.
15.Späth G.F., and S.M.Beverley, "An LPG-independent approach for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation", Exp. Parasitology, 2001 19:97-103.
16.Sacks D.L., Modi G., Rowton E., Späth G., Turco S.J. and S.M. Beverley, "The role of phosphoglycans in Leishmania-Sand Fly interactions", Proc. Natl. Acad. Sci. 2000 97:406-411.
17.Späth G., Epstein L., Leader B., Singer S., Avila H., Turco S.J. and S.M.Beverley, "LPG is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major", Proc. Natl. Acad. Sci., 2000 97:9258.
18.Späth G. and Weiss M.C., "Hepatocyte Nuclear Factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells, J. Cell Biol. 1998 4:935-946.
19.Bally A., Späth G., Bender V. and Weiss M.C., "Phenotypic effects of the forced expression of HNF4 and HNF1 are conditioned by properties of the recipient cell", J. Cell Sci. 1998 111:2411-2421.
20.Amicone L., Spagnoli F.M., Späth G., Giordano S., Tommasini C., Bernardini S., DeLuca V., Della Rocca C., Weiss, M.C., Comoglio P.M. and Tripodi M., "Immortalization of differentiated hepatocytes by transgenic expression of truncated Met", EMBO 1997 16:495-503.
21.Späth G. and Weiss M.C., "Hepatocyte Nuclear Factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells", Mol. Cell Biol. 1997 17:1913-1922.
22.Späth G., Ramadori G., Rittner C. and Schneider P., "Expression of the C8 genes during cytokine-mediated in vitro induction of the acute phase response", Exp. Clin. Immunogenet. 1995 12:53-60.