Publications

 

---2012---
 
JP Bourgeois, V Meas-Yeadid, AM Lesourd, P Faure, S Pons, U Maskos, JP Changeux, JC Olivo-Marin & S Granon (2012) Prefrontal nicotinic receptors mediate flexible choices during novelty exploration. Cerebral Cortex 22, 1007-1015.
 
M Besson, V David, P Cazala, J-P Guilloux, C Reperant, I Cloez-Tayarani, J-P Changeux, AM Gardier & S Granon (2012) Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology 220, 1-14.

J Chabout*, P Serreau*, E Ey, L Bellier, T Aubin, T Bourgeron & S Granon (2012) Adult male mice emit context-specific ultrasonic vocalizations that are modulated by prior isolation or group rearing environment. PLoS ONE 7:e29401

R Exley, JM McIntosh, M J Marks, U Maskos & SJ Cragg (2012) Striatal α5 nicotinic receptor subunit regulates dopamine release probability in dorsal striatum. J Neurosci 32, 2352-2356.
 
F de Chaumont, R Dos-Santos Coura, P Serreau, A Cressant, J Chabout, S Granon & J-C Olivo-Marin (2012) Computerized video analysis of social interactions in mice. Nature Methods 9, 410-417.
 
MJ Orejarena, A Herrera-Solís, S Pons, U Maskos, R Maldonado &P Robledo (2012) Selective Re-expression of β2 Nicotinic Acetylcholine Receptor Subunit in the Ventral Tegmental Area Restores intravenous Nicotine Self-Administration. Neuropharmacology EPub 28 March
 
S Tolu, R Eddine, F Marti, V David, M Graupner, S Pons, M Baudonnat, M Husson, M Besson, C Reperant, J Zemdegs, C Pagès, YAH Hay, B Lambolez, J Caboche, B Gutkin, AM Gardier, J-P Changeux, P Faure & U Maskos (2012) Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement.Mol Psychiatry EPub 3 July 


---2011---

R Exley*, N Maubourguet*, V David*, R Eddine, A Evrard, S Pons, F Marti, S Threlfell, P Cazala, JM McIntosh, J-P Changeux, U Maskos, SJ Cragg & P Faure (2011) Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine. Proc Natl Acad Sci U S A 108, 7577-7582.
 

ME Avale
, J Chabout, S Pons, P Serreau, F de Chaumont, JC Olivo-Marin, JP Bourgeois, U Maskos, JP Changeux& S Granon(2011) Prefrontal nicotinic receptors control novel social interaction between mice. FASEB J. 25, 2145-2155.
 
D Toulorge, S Guerreiro, A Hild, U Maskos, EC Hirsch&PP Michel(2011) Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+. FASEB J. 25, 2563-2573.
 
P Serreau, J Chabout, SV Suarez, J Naudé & S Granon (2011) Beta2-containing neuronal nicotinic receptors as major actors in the flexible choice between conflicting motivations. Behav Brain Res 225, 151-159.
 
S Frahm, MA Slimak, L Ferrarese, J Santos-Torres, B Antolin-Fontes, S Auer, S Filkin, S Pons, J-F Fontaine, V Tsetlin, U Maskos & I Ibanez-Tallon (2011) Aversion to nicotine is regulated by the balanced activity of b4 and α5 nicotinic receptor subunits in the medial habenula. Neuron 70, 522-535.
 
F Marti, O Arib, V Dufresne, U Maskos, P-J Corringer, R de Beaurepaire & P Faure (2011)Smoke extracts and nicotine, but not tobacco extracts, potentiate firing and burst activity of Ventral Tegmental Area dopaminergic neurons in mice. Neuropsycho-pharmacology 36, 2244-2257.
 
K Guillem, RB Poorthuis, B Bloem, M Loos, AB Smit, U Maskos, S Spijker & H Mansvelder (2011) Nicotinic acetylcholine receptor b2 subunits in the medial prefrontal cortex control attention. Science 333, 888-891.
 
 
 
 
---2010---

- S Tolu, ME Avale, H Nakatani, S Pons, F Tronche, H Monyer, J-P Changeux & U Maskos (2010) A versatile system for the neuronal subtype specific expression of lentiviral vectors. FASEB J. 24, 723-730.
- U Maskos (2010) Role of endogenous acetylcholine in the regulation of nicotinic receptors in the dopaminergic system. J. Neurochem. 114, 641-646.
- M Melis, S Carta, L Fattore,
S Tolu, S Yasar, SR Goldberg, W Fratta, U Maskos & M Pistis (2010) PPARα modulates dopamine neuron activity specifically through nicotinic receptors. Biol. Psychiatry 68, 256-264.
- O Arib, P Rat, R Molimard, A Chait, P Faure & R de Beaurepaire (2010) Electrophysiological characterization of harmane-induced activation of mesolimbic dopamine neurons. Eur. J. Pharmacol. 629, 47-52.
- C Reperant,
S Pons, E Dufour, H Rollema, AM Gardier & U Maskos (2010) Effect of the α4β2* nicotinic acetylcholine receptor (nAChR) partial agonist varenicline on dopamine release: a study in β2-/- mice with selective re-expression of the β2 nAChR subunit in the ventral tegmental area. Neuropharmacology 58, 346-350.
- M Besson, S Suarez, J-P Changeux & S Granon (2010) A low dose of nicotine is sufficient to produce nicotine withdrawal in mice. Health 2, 1-7.
- W Saba, H Valette,
S Granon, Y Xiao, KJ Kellar, F Dollé & M Bottlaender (2010) [18F]ZW-104, a new radioligand for imaging a2- a3- a4 / b2 central nicotinic acetylcholine receptors: evaluation in mutant mice. Synapse 64, 570-572.
- L Azam,
U Maskos, J-P Changeux, C Dowell, S Christensen, M De Biasi & JM McIntosh (2010) a-Conotoxin BuIA[T5A;P6O] discriminates between α6β4* and α6β2* nAChRs and blocks nicotine-stimulated norepinephrine release in mouse hippocampus. FASEB J., in press
- K Cambon, R Dos-Santos Coura, L Groc, A Carbon, D Weissmann, J-P Changeux, JF Pujol & S Granon (2010) Aggressive behavior during social interaction in mice is controlled by the modulation of tyrosine hydroxylase expression in the prefrontal cortex. Neuroscience Oct 19.
- AS Villégier, L Salomon, S Granon, N Champtiaux, J-P Changeux & J-P Tassin (2010) α7 and β2* nicotinic receptors control monoamine-mediated locomotor response. Neuroreport 21, 1085-1089.



---2009---

- S Suarez, A Amadon, E Giacomini, A Wiklund, J-P Changeux, D Le Bihan & S Granon (2008) Brain activation by short-term nicotine exposure in anesthetized wild-type and beta2-nicotinic receptors knockout mice: a BOLD fMRI study. Psychopharmacology 202, 599-610.
- A Wiklund, S Granon, P Faure, E Sundman, JP Changeux & LI Eriksson (2009) Object memory in young and aged mice after sevoflurane anaesthesia. Neuroreport 20, 1419-1423.
- K Maouche, M Polette, T Jolly, K Medjber, I Cloëz-Tayarani, J-P Changeux, H Burlet, C Terryn, C Coraux, J-M Zahm, P Birembaut & J-M Tournier (2009) α7 Nicotinic Acetylcholine Receptor Regulates Airway Epithelium Differentiation by Controlling Basal Cell Proliferation. Am. J. Pathology 175, 1868-1882.



---2008---

- ME Avale, P Faure, S Pons, P Robledo, T Deltheil, DJ David, AM Gardier, R Maldonado, S Granon, J-P Changeux & U Maskos (2008) Interplay of β2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proc. Natl. Acad. Sci. U S A 105, 15991-15996.
- S Pons, L Fattore, G Cossu, E Porcu, S Tolu, J-P Changeux, U Maskos* & W Fratta* (2008) Crucial role of α4 and α6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. J. Neurosci. 28, 12318-12327. *corresponding authors
- N Maubourguet, A Lesne, J-P Changeux, U Maskos & P Faure (2008) Behavioral sequence analysis reveals a novel role for ß2* nicotinic receptors in exploration. PLoS Computational Biology 4:e1000229
- A Wiklund, S Granon, I Cloez-Tayarani, P Faure, A-M Le Sourd, E Sundman, J-P Changeux & LI Eriksson (2008) Sevoflurane anesthesia alters exploratory and anxiety-like behavior in mice lacking the ß2 nicotinic acetylcholine receptor subunit. Anesthesiology 109, 790-798.
- N Even, A Cardona, M Soudant, P-J Corringer, J-P Changeux & I Cloëz-Tayarani (2008) Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport 19, 1545-1550.
- S Jamain, K Radyushkin, K Hammerschmidt, S Granon, S Boretius, F Varoqueaux, N Ramanantsoa, J Gallego, A Ronnenberg, D Winter, J Frahm, J Fischer, T Bourgeron, H Ehrenreich & N Brose (2008) Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proc Natl Acad Sci U S A 105, 1710-1715.
- F Marti, H Korn & P Faure (2008) Interplay between subthreshold potentials and γ oscillations in Mauthner cell’s presynaptic inhibitory interneurons. Neuroscience 151, 983-994.
- M Besson, S Suarez, A Cormier, J-P Changeux & S Granon (2008) Chronic nicotine exposure has dissociable behavioural effects on control and beta2-/- mice. Behav Genet 38, 503-514.
- U Maskos (2008) The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology. Brit. J. Pharmacol. 153, S438-445.



---2007---

- A Cressant, M Besson, S Suarez, A Cormier & S Granon (2007) Spatial learning in Long-Evans Hooded rats and C57BL/6J mice: Different strategies for different performance. Behav. Brain Res. 177, 22-29.
- N Moser, I Jones, N Mechawar, A Gochberg-Sarver, A Orr-Urtreger, M Plomann, U Roth, U Maskos, U Winzer-Serhan, J-P Bourgeois, L Marubio, M de Biasi, R Salas, B Molles, H Schröder, J Lindstrom, A Maelicke, J-P Changeux & A Wevers (2007) Evaluation of the specificity of nicotinic acetylcholine receptor antibodies in receptor-deficient mice. J. Neurochem. 102, 479-492.
- M Besson, S Granon, M Mameli-Engvall, I Cloez-Tayarani, N Maubourguet, A Cormier, P Cazala, V David, J-P Changeux, P Faure (2007) Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proc. Natl. Acad. Sci. USA 104, 8155-8160.
- A Zanardi, R Ferrari, G Leo, U Maskos, J-P Changeux & M Zoli (2007) Loss of high affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment. FASEB J. 21, 4028-4037.
- C Agulhon, JC Platel, B Kolomiets, V Forster, S Picaud, J Brocard, P Faure & P Brulet (2007) Bioluminescent imaging of Ca2+ activity reveals spatiotemporal dynamics in glial networks of dark-adapted mouse retina. J. Physiol. (London) 583, 945-958.
- I Roszko, P Faure & L Mathis (2007) Stem cell growth becomes predominant while neural plate progenitor pool decreases during spinal cord elongation. Dev. Biol. 304, 232-245.
- U Maskos (2007) Emerging concepts: Novel integration of in vivo approaches to localise the function of nicotinic receptors.J. Neurochem. 100, 596-602.



---2006---

- M Mameli-Engvall, A Evrard, S Pons, U Maskos, T Svensson, J-P Changeux & P Faure (2006) Hierarchical Control of Dopamine Neuron-Firing Patterns by Nicotinic Receptors. Neuron 50, 911-921.
- P Vincent*, U Maskos*, I Charvet, L Bourgeais, L Stoppini, R Lambert, J-P Changeux, P Meda & D Tritsch (2006) Live imaging of neural structure and function by fibered confocal fluorescence microscopy. EMBO Rep. 7, 1154-1161. *equal contribution
- BE Molles, U Maskos, S Pons, M Besson, BP Guiard, J-P Guilloux, A Evrard, P Cazala, A Cormier, M Mameli-Engvall, N Dufour, I Cloëz-Tayarani, A-P Bemelmans, J Mallet, AM Gardier, V David, P Faure, S Granon & J-P Changeux (2006) Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. J. Mol. Neurosci. 30, 105-106.
- B Bathellier, S Lagier, P Faure & PM Lledo (2006) Circuit properties generating gamma oscillations in a network model of the olfactory bulb. J Neurophysiol. 95, 2678-91.
- M Besson, V David, S Suarez, A Cormier, P Cazala, JP Changeux & S Granon (2006) Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome. Psychopharmacology (Berl) 187, 189-99.
- V David, M Besson, JP Changeux, S Granon & P Cazala (2006) Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology 50, 1030-40.
- AS Villégier, L Salomon, S Granon, JP Changeux, JD Belluzzi, FM Leslie & JP Tassin (2006) Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology 31, 1704-13.
- S Granon & J-P Changeux (2006) Attention-deficit/hyperactivity disorder: a plausible mouse model? Acta Paediatrica 95, 645-649.
- U Maskos, S Granon, P Faure & J-P Changeux (2006) The location, structure and function of nicotinic acetylcholine receptors in the central nervous system: development of a novel method of stereotaxic gene re-expression in knockout mice. In «Novartis Foundation Symposium 275, Understanding nicotine and tobacco addiction.» John Wiley, Chichester, pp. 62-84.



---2005---

- U Maskos, BE Molles, S Pons, M Besson, BP Guiard, J-P Guilloux, A Evrard, P Cazala, A Cormier, M Mameli-Engvall, N Dufour, I Cloëz-Tayarani, A-P Bemelmans, J Mallet, AM Gardier, V David, P Faure, S Granon & J-P Changeux (2005) Recovery of nicotine reinforcement and cognitive functions by targeted expression of nicotinic receptors. Nature 436, 99-106.
- J Sallette, S Pons, A Devillers-Thiery, M Soudant, L Prado de Carvalho, JP Changeux & PJ Corringer (2005) Nicotine upregulates its own receptors through enhanced intracellular maturation. Neuron 46, 595-607.



---2004---

- E Mordelet, K Kissa, A Cressant, F Gray, S Ozden, C Vidal, P Charneau & S Granon (2004) Histopathological and cognitive defects induced by Nef in the brain. FASEB J. 18, 1851-1861.
- M Cordero-Erausquin, S Pons, P Faure & JP Changeux (2004) Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain 109, 308-318.
- S Pons, J Sallette, JP Bourgeois, A Taly, JP Changeux & A Devillers-Thiery (2004) Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric alpha7-5HT3A receptor. Eur. J. Neurosci. 20, 2022-2030.
- J Sallette, S Bohler, P Benoît, M Soudant, S Pons, N Le Novère, JP Changeux & PJ Corringer (2004) An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. J Biol. Chem. 279, 18767-18775.
- R Grailhe, L Prado de Carvalho, Y Paas, C Le Poupon, M Soudant, P Bregestovski, JP Changeux & PJ Corringer (2004) Distinct subcellular targeting of fluorescent nicotinic alpha3 beta4 and serotoninergic 5-HT3A receptors in hippocampal neurons. Eur. J. Neurosci. 19, 855-862.
- C Beloin, J Valle, P Latour-Lambert, P Faure, M Kzreminski, D Balestrino, JA Haagensen, S Molin, G Prensier, B Arbeille & JM Ghigo (2004) Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression. Mol Microbiol. 51, 659-674.



---2003---

- U Maskos & RDG McKay (2003) Neural cells without functional N-Methyl-D-Aspartate (NMDA) receptors contribute extensively to normal postnatal brain development in efficiently generated chimaeric NMDA R1 -/- <--> +/+ mice. Dev. Biol. 262, 119-136.
- A Cressant & S Granon (2003) Definition of a new maze paradigm for the study of spatial behavior in rats. Brain Res Brain Res Protoc. 12, 116-124.
- S Granon, P Faure & JP Changeux (2003) Executive and social behaviors under nicotinic receptor regulation. Proc Natl Acad Sci U S A 100, 9596-9601.
- F Cazalis, R Valabrègue, M Pélégrini-Issac, S Asloun, TW Robbins & S Granon (2003) Individual differences in prefrontal cortical activation on the Tower of London planning task: implication for effortful processing. Eur J Neurosci. 17, 2219-2225.
- P Faure, H Neumeister, D Faber & H Korn (2003) Symbolic Analysis of swimming trajectories reveals scale invariance and provides a model for fish locomotion. Fractals 11, 233-243.
- H Korn & P Faure (2003)  Is there chaos in the brain? II. Experimental evidence and related models. C R Biol. 326, 787-840.



---2002---

- U Maskos, K Kissa, C St Cloment & P Brûlet (2002) Retrograde trans-synaptic transfer of green fluorescent protein allows the genetic mapping of neuronal circuits in transgenic mice. Proc. Natl. Acad. Sci. U S A 99, 10120-10125.



---2001---
- U Maskos, O Brüstle & RDG McKay (2001) Long-term survival, migration, and differentiation of neural cells without functional NMDA receptors in vivo. Dev. Biol. 231, 103-112.