Dynamic Neuronal Imaging / Publications


Fink AE., Bender, KJ., Trussell, LO., Otis, TS. and DiGregorio, DA. Two-photon compatibility and single-voxel, single-trial detection of subthreshold neuronal activity by a two-component optical voltage sensor. PLoS One, 7(8):e41434 (2012).

2.        Abrahamsson, T., Cathala, L., Matsui, K., Shigemoto, R., and DiGregorio, DA. Thin dendrites of cerebellar interneurons confer sublinear synaptic integration and a gradient of short-term plasticity. Neuron, 73: 1159-1172 (2012).

DiGregorio, D.A. Confocal spot detection of presynaptic Ca2+ domains. Optical Imaging in Neuroscience: A Laboratory Manual. Cold Spring Harbor Laboratory Press (in press).

Bradley, J., Luo, R., Otis, T.S. and DiGregorio, D.A. Submillisecond optical reporting of membrane potential in situ using a neuronal tracer dye. Journal of Neuroscience, 29(29):9197–9209 (2009).

Lutz, C, Otis, T, DeSars, V., Charpak S., DiGregorio, D. A., and Emiliani, V. Holographic photolysis of caged neurotransmitters. Nature Methods, 5(9):821-827 (2008).

DiGregorio, D.A., Rothman, J., Nielsen, T., and Silver, R.A. Desensitization Properties of AMPA Receptors at the Cerebellar Mossy Fiber–Granule Cell Synapse Journal of Neuroscience, 27(31):8344–8357 (2007).

Cathala, L., Holderith, N.B., Nusser, Z., DiGregorio, D.A., Cull-Candy, S.G. Changes in synaptic structure underlie the developmental speeding of AMPA receptor-mediated EPSCs. Nature Neuroscience8(10):1310-8 (2005).

Nielsen, T., DiGregorio, D.A., Silver, R.A. Modulation of glutamate mobility reveals the mechanism underlying slow-rising AMPA receptor EPSCs and the diffusion coefficient in the synaptic cleft. Neuron, 42:757-771 (2004).

DiGregorio, D.A., Nusser, Z., Silver, R.A. Spillover of glutamate onto synaptic AMPA receptors enhances fast transmission at a cerebellar synapse. Neuron 35:512-533(2002).

DiGregorio, D.A., Peskoff, A., and Vergara, J.L. Measurement of action potential-induced presynaptic calcium domains at a cultured neuromuscular junction. Journal of Neuroscience, 19(18):7846-7859 (1999).