Publications
2008
Bocquet, N., Nury, H., Baaden, M., Le Poupon, C., Changeux, J.P., Delarue, M., Corringer, P.J. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation, Nature, advance online publication
Even, N., Cardona, A., Soudant, M., Corringer, P.J., Changeux, J.P., Cloëz-Tayarani, I. Regional differential effects of chronic nicotine on brain alpha4-containing and alpha6-containing receptors. Neuroreport. 19(15):1545-50
Corringer, P.J. and Changeux, J.P. Nicotinic acetylcholine receptors. Scholarpedia, 3(1):3468 http://www.scholarpedia.org/article/Nicotinic_acetylcholine_receptors’>
2007
Bocquet, N., Prado de Carvalho, L., Cartaud, J., Neyton, J., Le Poupon, C., Taly, A., Grutter, T., Changeux, J.P., Corringer, P.J. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family, Nature, 445: 116-119
Selected previous publications from the principal investigator :
Taly, A., Corringer, P.J., Grutter, T., Prado de Carvalho L., Karplus, M., Changeux, J.P. Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A. 103:16965-16970 (2006)
Sallette, J.,Pons, S., Devillers-Thiery A., Soudant, M., Prado de Carvalho, L., Changeux J.P. and Corringer, P.J., Nicotine up-regulates its own receptors through enhanced intracellular maturation, Neuron, 46:595-607 (2005)
Taly, A., Delarue, M., Grutter, T., Nilges, M., Le Novère, N., Corringer, P.J., Changeux, J.P. A quaternary twist model for nicotinic receptor gating, Biophys. J. 88(6):3954-65 (2005)
Sallette J., Bohler S., Benoit P., Soudant M., Pons S., Le Novere N., Changeux J.P., Corringer, P.J., An extracellular microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. J. Biol. Chem. 279(18):18767-75 (2004)
Grailhe R., de Carvalho L.P., Paas Y., Le Poupon C., Soudant M., Bregestovski P., Changeux J.P., Corringer, P.J., Distinct subcellular targeting of fluorescent nicotinic alpha3beta4 and serotoninergic 5-HT3A receptors in hippocampal neurons. Eur. J. Neurosci. 19(4):855-62 (2004)
Grutter, T., Prado de Carvalho, L., Le Novère, N., Corringer, P.J., Edelstein, S.J. Changeux, J.P. An interaction between two residues from different loops of the acetylcholine-binding site contributes to the activation mechanism of nicotinic receptors. EMBO J, 22:1990-2003 (2003)
Martinez, K.L., Gohon, Y., Corringer, P.J., Tribet, C., Merola, F., Changeux, J.P., Popot, J.L. Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs physical constraints. FEBS Letters 26515: 1-6 (2003)
Fruchart-Gaillard, C., Gilquin, B., Antil-Delbeke, S., Le Novere, N., Tamiya, T., Corringer, P.J., Changeux J.P., Menez A., Servent D., Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proc Natl Acad Sci U S A. 5;99(5):3216-3221 (2002)
Fischer, M., Corringer, P.J., Schott, K.,Bacher, A., Changeux, J.P. A new method for soluble overexpression of the alpha7 nAChR extracellular domain. Proc Natl Acad Sci U S A., 98:3567-3570 (2001)
Corringer, P.J., Le Novère N. and Changeux J.P. Nicotinic receptors at the amino acid level. Ann. Rev. Pharmacol. Toxicol, 40:431-458 (2000)
Martinez, K., Corringer, P.J., Edelstein, S.J., Changeux, J.P., Mérola, F. Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time resolved fluorescence spectroscopy. Biochemistry, 39: 6979-6990 (2000)
Le Novère, N., Corringer, P.J., Changeux, J.P. Improved secondary structure prediction of a nicotinic receptor subunit. Incorporation of solvent accessibility and experimental data into a 2D representation. Biophys. J. 76: 2329-2345 (1999)
Corringer, P.J., Bertrand, S, Galzi, J.L., Devillers-Thiéry, A., Changeux J.P. et Bertrand, D. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron, 22: 831-843 (1999)
Corringer, P.J., Bertrand, S., Bohler, S., Edelstein, S., Changeux, J.P., Bertrand, D. Identification of critical elements determining agonist binding and desensitization of neuronal nicotinic acetylcholine receptors. J. Neuroscience 18(2):648-657 (1998)
Galzi, J.L., Bertrand, S., Corringer, P.J., Changeux, J.P., Bertrand, D. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. EMBO J. 15: 5824-5832 (1996)
Corringer, P.J., Galzi, J.L., Eiselé, J.L., Bertrand, S., Changeux, J.P., Bertrand, D. Identification of a new component of the agonist binding site of the nicotinic alpha7 homooligomeric receptor. J. Biol. Chem. 270: 11749-11752 (1995)
Corringer, P.J., Weng, J.H., Ducos, B., Durieux, C., Boudeau, P., Bohme, A., Roques, B.P. CCK-B agonist and antagonist activities of structurally hindered and peptidase-resistant Boc-CCK4 derivatives. J. Med. Chem. 36: 166-172 (1993)
Bocquet, N., Nury, H., Baaden, M., Le Poupon, C., Changeux, J.P., Delarue, M., Corringer, P.J. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation, Nature, advance online publication
Even, N., Cardona, A., Soudant, M., Corringer, P.J., Changeux, J.P., Cloëz-Tayarani, I. Regional differential effects of chronic nicotine on brain alpha4-containing and alpha6-containing receptors. Neuroreport. 19(15):1545-50
Corringer, P.J. and Changeux, J.P. Nicotinic acetylcholine receptors. Scholarpedia, 3(1):3468 http://www.scholarpedia.org/article/Nicotinic_acetylcholine_receptors’>
2007
Bocquet, N., Prado de Carvalho, L., Cartaud, J., Neyton, J., Le Poupon, C., Taly, A., Grutter, T., Changeux, J.P., Corringer, P.J. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family, Nature, 445: 116-119
Selected previous publications from the principal investigator :
Taly, A., Corringer, P.J., Grutter, T., Prado de Carvalho L., Karplus, M., Changeux, J.P. Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A. 103:16965-16970 (2006)
Sallette, J.,Pons, S., Devillers-Thiery A., Soudant, M., Prado de Carvalho, L., Changeux J.P. and Corringer, P.J., Nicotine up-regulates its own receptors through enhanced intracellular maturation, Neuron, 46:595-607 (2005)
Taly, A., Delarue, M., Grutter, T., Nilges, M., Le Novère, N., Corringer, P.J., Changeux, J.P. A quaternary twist model for nicotinic receptor gating, Biophys. J. 88(6):3954-65 (2005)
Sallette J., Bohler S., Benoit P., Soudant M., Pons S., Le Novere N., Changeux J.P., Corringer, P.J., An extracellular microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. J. Biol. Chem. 279(18):18767-75 (2004)
Grailhe R., de Carvalho L.P., Paas Y., Le Poupon C., Soudant M., Bregestovski P., Changeux J.P., Corringer, P.J., Distinct subcellular targeting of fluorescent nicotinic alpha3beta4 and serotoninergic 5-HT3A receptors in hippocampal neurons. Eur. J. Neurosci. 19(4):855-62 (2004)
Grutter, T., Prado de Carvalho, L., Le Novère, N., Corringer, P.J., Edelstein, S.J. Changeux, J.P. An interaction between two residues from different loops of the acetylcholine-binding site contributes to the activation mechanism of nicotinic receptors. EMBO J, 22:1990-2003 (2003)
Martinez, K.L., Gohon, Y., Corringer, P.J., Tribet, C., Merola, F., Changeux, J.P., Popot, J.L. Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs physical constraints. FEBS Letters 26515: 1-6 (2003)
Fruchart-Gaillard, C., Gilquin, B., Antil-Delbeke, S., Le Novere, N., Tamiya, T., Corringer, P.J., Changeux J.P., Menez A., Servent D., Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proc Natl Acad Sci U S A. 5;99(5):3216-3221 (2002)
Fischer, M., Corringer, P.J., Schott, K.,Bacher, A., Changeux, J.P. A new method for soluble overexpression of the alpha7 nAChR extracellular domain. Proc Natl Acad Sci U S A., 98:3567-3570 (2001)
Corringer, P.J., Le Novère N. and Changeux J.P. Nicotinic receptors at the amino acid level. Ann. Rev. Pharmacol. Toxicol, 40:431-458 (2000)
Martinez, K., Corringer, P.J., Edelstein, S.J., Changeux, J.P., Mérola, F. Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time resolved fluorescence spectroscopy. Biochemistry, 39: 6979-6990 (2000)
Le Novère, N., Corringer, P.J., Changeux, J.P. Improved secondary structure prediction of a nicotinic receptor subunit. Incorporation of solvent accessibility and experimental data into a 2D representation. Biophys. J. 76: 2329-2345 (1999)
Corringer, P.J., Bertrand, S, Galzi, J.L., Devillers-Thiéry, A., Changeux J.P. et Bertrand, D. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron, 22: 831-843 (1999)
Corringer, P.J., Bertrand, S., Bohler, S., Edelstein, S., Changeux, J.P., Bertrand, D. Identification of critical elements determining agonist binding and desensitization of neuronal nicotinic acetylcholine receptors. J. Neuroscience 18(2):648-657 (1998)
Galzi, J.L., Bertrand, S., Corringer, P.J., Changeux, J.P., Bertrand, D. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. EMBO J. 15: 5824-5832 (1996)
Corringer, P.J., Galzi, J.L., Eiselé, J.L., Bertrand, S., Changeux, J.P., Bertrand, D. Identification of a new component of the agonist binding site of the nicotinic alpha7 homooligomeric receptor. J. Biol. Chem. 270: 11749-11752 (1995)
Corringer, P.J., Weng, J.H., Ducos, B., Durieux, C., Boudeau, P., Bohme, A., Roques, B.P. CCK-B agonist and antagonist activities of structurally hindered and peptidase-resistant Boc-CCK4 derivatives. J. Med. Chem. 36: 166-172 (1993)