Main publications

Main publications


1 - Roy E., Bruyère J., Flamant P., Bigou S., Ausseil J., Vitry S., Heard J.M. (2011) GM130 gain-of-function induces cell pathology in a model of lysosomal storage disease. Hum Mol Genet, Dec 30, PMID 22156940
 
2 - Lemonnier T., Blanchard S., Toli D., Roy E., Bigou S., Froissart R., Rouvet I., Vitry S., Heard J.M., Bohl D (2011). Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells. Hum Mol Genet, 20, 3653-3666.
 
3 - Ellinwood M., Ausseil J., Desmaris N., Bigou S., Liu S., Jens J.J., Snella E.M.,
Mohammed E., Thomson C., Raoul S., Joussemet B., Roux F., Chérel Y., Lajat Y., Piraud M., Benchaouir R., Hermening S., Petry H., Froissart R., Tardieu M., Ciron C., Moullier P., Parkes J., Kline K., Maire I., Vanier M.T., Heard J.M., Colle M.A. (2011) Safe, efficient and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes. Mol Ther, 19, 251-259.
 
4 - Vitry S., Bruyère J., Hocquemiller M., Bigou S., Ausseil J., Colle M.A., Prévost M.C., Heard J.M. (2010) Storage vesicles in neurons are related to Golgi complex alterations in mucopolysaccharidosis IIIB. Am J Pathol, 177, 2984-2999.
 
5 - Bohl D, Liu S, Blanchard S, Hocquemiller M, Haase G, Heard JM. (2008) Directed evolution of motor neurons from genetically engineered neural precursors. Stem Cells. 10, 2564-2575.