Research / Interactions Bacteriophages-Bacteria in Animals / Research / Gut colonization model with Escherichia coli

Gut colonization model with Escherichia coli

Escherichia coli is a predominant commensal bacteria of the human intestinal facultative anaerobic flora. However, some strains are responsible for intestinal or extra-intestinal diseases in humans. We use a model to study the ecology of interactions in the short and long term between bacteriophages and a pathogenic strain of E. coli within in a complex microbial environment.  

Ecoli-Phage

References


Maura D, Morello E, du Merle L, Bomme P, Le Bouguénec C, L. Debarbieux (2011) Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice. Environ. Microbiol. 14(8):1844-1854.
 
Maura D, Galtier M, Le Bouguénec C, Debarbieux L. (2012) Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine. Antimicrob Agents Chemother. 56(12):6235-6242.
 
Maura D, Debarbieux L. (2012) On the interactions between virulent bacteriophages and bacteria in the gut. Bacteriophage. 2(4):229-233.