Team members / David Prangishvili / Publications

D. Prangishvili - publications

86. Forterre, P., and D. Prangishvili. 2009. The great billion-year war between ribosome- and capsid-encoding organisms (cells and viruses) as the major source of evolutionary novelties. Annals of the New York Academy of Sciences, in press.

85. Basta T., J. Smyth, P. Forterre, D. Prangishvili, and X. Peng. 2009. Novel archaeal plasmid pAH1 and its interactions with the lipothrixvirus AFV1. Molecular Microbiology 71, 23-34.


84. Vestergaard G., S. A. Shah, A. Bize, W. Reitberger, M. Reuter, H. Phan, A. Briegel, R. Rachel, R. A. Garrett and D. Prangishvili. 2008. Stygiolobus rod-shaped virus and the interplay of crenarchaeal rudiviruses with the anti-viral CRISPR system. Journal of Bacteriology, 190, 6837-6845.


83. Steinmetz, N. F., A. Bize, R. C. Findlay, G. P. Lomonossoff, M. Manchester, D. J. Evans, and D. Prangishvili. 2008. Site-specific and spatially controlled addressability of a new viral nanobuilding block: Sulfolobus islandicus rod-shaped virus 2,
Advanced Functional Materials, 18, 3478-3486.


82. Sutter M., D. Boehringer, S. Gutmann, S. Günther, D. Prangishvili, M. J. Loessner, K. O. Stetter, E. Weber-Ban and N. Ban. 2008. Structural basis of enzyme encapsulation into a bacterial nanocompartment. Nature Structural & Molecular Biology, 15, 939 – 947.


81. Comeau, A. M., G. F. Hatfull, H. M. Krisch, D. Lindell, N. H. Mann, and D. Prangishvili. 2008. Exploring the prokaryotic virosphere. Research in Microbiology, 159, 306-313.


80. Bize, A., X., Peng, M. Prokofeva, K. MacLellan, S. Lucas, P. Forterre, R. A. Garrett, E. A. Bonch-Osmolovskaya, and D. Prangishvili. 2008. Viruses in acidic geothermal environments of the Kamchatka Peninsula. Research in Microbiology, 159, 358-366.


79. Prangishvili, D., T. Basta, and R. A. Garrett. 2008. Crenarchaeal viruses: Morphotypes and Genomes. In Encyclopedia of Virology (B. W. J. Mahy and M. van Regenmortel, eds.), pp. 587-595, Oxford: Elsevier.

78. Basta, T., R. A. Garrett, and D. Prangishvili. 2008. Viruses of the Archaea, In Encyclopedia of Life Sciences (Article nr. A42991) John Wiley & Sons, Ltd: Chichester http://www.els.net/ [DOI: 10.1002/9780470015902.a0000774.pub2]

77. Vestergaard, G., R. Aramayo, T. Basta, M. Häring, X. Peng, K. Brügger, L. Chen, R. Rachel, N. Biosset, R. A. Garrett, and D. Prangishvili. 2008. Structure of the Acidianus Filamentous Virus 3 and comparative genomics of related archaeal lipothrixviruses. Journal of Virology 82, 371-381.


76. Basta, T., and D. Prangishvili. 2007. Nanobiotechnological potential of viruses of hyperthermophilic archaea. In Thermophiles: Biology and Technology at High Temperatures (F. Robb, G. Antranikian, D. Grogan, and A. Driessen, eds). pp. 225-235, CRC Press, Boca Raton.

75. Peng, X., T. Basta, M. Haring, R. A. Garrett, and D. Prangishvili. 2007. Genome of Acidianus bottle-shaped virus and insights into the replication and packaging mechanisms. Virology 364, 237-243.


74. Keller, J. N. Leulliot, C. Cambillau, V. Campanacci, S. Porciero, D. Prangishvili, P. Forterre, D. Cortez, S. Quevillon-Cheruel, and H. van Tilbeurgh. 2007. Crystal Structure of AFV3-109, a highly conserved protein from crenarchaeal viruses. BMC Virology Journal 4, 12.

73. Prangishvili, D. 2007. Families of viruses infecting crenarchaeota. In Archae: Evolution, Physiology and Molecular Biology. (R. A. Garrett and H.-P. Klenk, eds.) pp. 59-74. Blackwell Publishing, Oxford.

72. Prangishvili, D., P. Forterre, and R. A. Garrett. 2006. Viruses of the Archaea: a unifying view. Nature Reviews Microbiology 4, 837-848.


71. Kessler, A., G. Sezonov, J. I. Guijarro, N. Desnous, T. Rose, M. Delepierre, S. Bell, and D. Prangishvili. 2006. A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters. Nucleic Acids Research 34, 4837-4845.


70. Huber, H., and D. Prangishvili. 2006. Sulfolobales. In: The Prokaryotes (Dworkin, M., Falkow, S., Rosenberg, E., Schleifer, K.-H., and Stackebrandt, E., eds.) 3rd Edition, vol. 3, pp. 23-51, Springer, New York.

69. Goulet, A., S. Spinelli, V. Campanacci, S. Porciero, S. Blangy, R. A. Garrett, H. van Tilbeurgh, N. Leulliot, D. Prangishvilli, and C. Cambillau. 2006. Crystallization and Preliminary X-ray Diffraction analysis of ORF14 from Sulfolobus Islandicus Filamentous Virus (SIFV). Acta Crystallographica F, 62, 884–886.


68. Prangishvili, D., G. Vestergaard, M. Häring, R. Aramayo, T. Basta, R. Rachel, and R. A. Garrett, R. A. 2006. Structural and genomic properties of the hyperthermophilic archaeal virus ATV with an extracellular stage of the reproductive cycle. Journal of Molecular Biology, 359, 1203-1216.


67. Prangishvili, D., R. A. Garrett, and E. V. Koonin. 2006. Evolutionary genomics of archaeal viruses: unique viral genomes in the third domain of life. Virus Research, 117, 52-67.


66. Stedman, K. M., D. Prangishvili, and W. Zillig. 2006. Viruses of Archaea. In The Bacteriophages (R. Calender, ed.) 2nd edition. Oxford University Press, New York, pp. 499-516.

65. Prangishvili D. 2006. Hyperthermophilic virus-host systems: detection and isolation. In Methods in Microbiology vol. 35 - Extremophiles (F. A. Rainey, and A. Ohren, eds.) pp. 329-345, Elsevier, Amsterdam.

64. Prangishvili, D., and R. A. Garrett. 2005. Hyperthermophilic crenarchaeal viruses. Trends in Microbiology, 13, 535-542.


63. Häring M., G. Vestergaard, K. Brügger, R. Rachel, R. A. Garrett, and D. Prangishvili. 2005. Independent virus development outside a host. Nature 436, 1101-1102.


62. Häring M., R. Rachel, X. Peng, R. A. Garrett, and D. Prangishvili. 2005. Diverse viruses in hot springs of Pozzuoli, Italy, including a unique bottle-shaped archaeal virus ABV from a new family, the Ampullaviridae. Journal of Virology 147, 2419-2429.


61. Häring M., R., G. Vestergaard, L. Chen, R. Rachel, R. A. Garrett, and D. Prangishvili. 2005. Structure and genome organisation of AFV2, a novel archaeal lipothrixvirus with unusual terminal and core structures. Journal of Bacteriology 187, 3855-3858.


60. Vestergaard, G., M. Häring, X. Peng, R. Rachel, R. A. Garrett, and D. Prangishvili. 2005. A novel rudivirus, ARV1, of the hyperthermophilic archaeal genus Acidianus. Virology 336, 83-92.


59. Kessler, A., B. Brinkman, J. van der Oost, and D. Prangishvili. 2004. Transcription of the rod-shaped viruses SIRV1 and SIRV2 of the hyperthermophilic archaeon Sulfolobus. Journal of Bacteriology 186, 7745-7753.


58. Peng, X., A. Kessler, H. Phan, R. A. Garrett, and D. Prangishvili. 2004. Multiple variants of the archaeal DNA rudivirus SIRV1 in a single host and a novel mechanism of genomic variation. Molecular Microbiology 54, 366-375.


57. Häring M., X. Peng, K. Brügger, R. Rachel, K. O. Stetter, R. A. Garrett, and D. Prangishvili. 2004. Morphology and genome organisation of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: a novel virus family, the Globuloviridae. Virology 323, 232-242.


56. Prangishvili, D., and R. A. Garrett. 2004. Exceptionally diverse morphotypes and genomes of crenarchaeal hyperthermophilic viruses. Biochemical Society Transactions 32, 204-208.


55. Bettstetter M., X. Peng, R. Rachel, R. A. Garrett, and D. Prangishvili. 2003. AFV1, a novel virus of the hyperthermophilic crenarchaeon Acidianus. Virology 315, 68-79.


54. Prangishvili D. 2003. Evolutionary insights from studies on viruses of hyperthermophilic archaea. Research in Microbiology 154, 289-294.


53. Rachel R., M. Bettstetter, B. Hedlund, M. Häring, A. Kessler, K.O. Stetter, and
D. Prangishvili. 2002. Remarkable diversity of viruses and virus-like particles in hot terrestrial environments. Archives of Virology 147, 2419-2429.


52. Prangishvili D., and W. Zillig. 2002. Rudivirus. In The Springer Index of Viruses (C. A. Tidona, and G. Darai, eds.) pp. 1086-1087, Springer, Berlin-Heidelberg.

51. Peng X., H. Blum, Q. She, S. Mallok, K. Brügger, R. A. Garrett, W. Zillig, and
D. Prangishvili. 2001. Sequences and replication of genomes of the archaeal viruses SIRV1 and SIRV2: Relationships to the archaeal lipothrixvirus SIFV and some eukaryal viruses. Virology 291, 226-234.


50. Blum, H., W. Zillig, S. Mallock, H. Domdey, and D. Prangishvili. 2001. The genome of the archaeal virus SIRV1 has features in common with genomes of eukaryal viruses. Virology 281, 6-9


49. Prangishvili D., and W. Zillig. 2001. Viruses of the Archaea. In Encyclopedia of Genetics (J. Miller, and S. Brenner, eds.), vol. 4, pp. 2114-2116, Academic Press, San Diego.

48. Birkenbihl R. P., K. Neef, D. Prangishvili, and B. Kemper. 2001. Holliday junction resolving enzymes of archaeal viruses SIRV1 and SIRV2. Journal of Molecular Biology 309, 1067-1076.


47. Prangishvili, D., K. Stedman, and W. Zillig. 2001. Viruses of the extremely thermophilic archaeon Sulfolobus. Trends in Microbiology 9, 39-42.


46. Stedman, K. M., Q. She, H. Phan, I. Holz, H. Singh, D. Prangishvili, R. Garrett, and W. Zillig. 2000. The pING family of conjugative plasmids from the extremely thermophilic archaeon Sulfolobus islandicus demonstrates modes of genomic variation and conjugation in crenarchaeota. Journal of Bacteriology 182, 7014-7020.


45. Prangishvili, D., I. Holz, E. Stieger, S. Nickell, J. K. Kristjansson, and W. Zillig. 2000. Sulfolobicins, specific proteinaceous toxins produced by strains of the extremely thermophilic archaeal genus Sulfolobus. Journal of Bacteriology 182, 2985-2988.


44. Arnold, H. P., Q. She, H. Phan, K. Stedman, D. Prangishvili, I. Holz, J. Kristjansson,
R. A. Garrett, and W. Zillig. 1999. The genetic element pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus. Molecular Microbiology 34, 217-226.


43. Prangishvili, D, H. P. Arnold, U. Ziese, D. Goetz, I. Holz, and W. Zillig. 1999. A novel virus family, the Rudiviridae: structure, virus-host interactions and genome variability of Sulfolobus viruses SIRV1 and SIRV2. Genetics 153, 1387-1396.


42. Prangishvili D., S.-V. Albers, I. Holz, H. P. Arnold, K. Stedman, T. Klein, H. Singh, J. Hiort , A. Schweier, J.K. Kristjansson, and W. Zillig. 1998. Conjugation in Archaea: frequent occurance of conjugative plasmids in Sulfolobus. Plasmid 40, 190-202.


41. Prangishvili, D., H.-P. Klenk, G. Jakobs, A. Schmiechen, C. Hanselman, I. Holz, and W. Zillig. 1998. Biochemical and Physiological characterization of the dUTPase from the archaeal virus SIRV. Journal of Biological Chemistry. 273, 6024-6029.


40. Zillig., W., H.P. Arnold, I. Holz, D. Prangishvili, A. Schweier, K. Stedman, Q.She, H. Phan, R. Garrett, and J.K. Kristjansson. 1998. Genetic elements in the extremely thermophilic archaeon Sulfolobus. Extremophiles 2, 131-140.


39. Zillig, W, D. Prangishvili, C. Schleper, M. Elferink, I. Holz, S. Albers, D. Janekovic, and D. Goetz. 1996. Viruses, plasmids and other genetic elements of thermophilic and hyperthermophilic archaea. FEMS Microbiology Reviews 18, 225-236.

38. Datukishvili, N., D. Poklok, F. Lottspeich, D. Prangishvili, and V. Rechinsky. 1996. The DNA polymerase encoding gene from a thermoacidophilic archaeon Sulfolobus acidocaldarius. Gene 177, 271-273.


37. Prangishvili, D., and H. P. Klenk. 1995. A homolog of the small subunit of penicillin acylase is encoded in the genome of the extremely thermophilic archaeon Sulfolobus solfataricus. Systematic and Applied Microbiology 17, 169-171.

36. Prangishvili, D., and H.P. Klenk, 1994. A gene for 74 kDa DNA polymerase from the archaeon Sulfolobus solfataricus. Systematic and Applied Microbiology 16, 665-671.

35. Prangishvili, D., and H. P. Klenk. 1993. Nucleotide sequence of the gene for for 74 kDa DNA polymerase from the archaeon Sulfolobus solfataricus. Nucleic Acids Research 21. 2768.


34. Datukishvili N., M. Nanazashvili, Kh. Kvantaliani, and D. Prangishvili. 1992. Characterization of antibodies obtained against DNA polymerase A of archaebacterium Sulfolobus acidocaldarius. Bulletin of the Georgian Academy of Sciences, Biol. Series 18, 76-282.

33. Prangishvili, D., and G. Muskhelishvili. 1991. Eukaryotic Features of thermoacidophilic Archaebacteria. In: Soviet Scientific Reviews, section D, vol. 10, pp.1-43, Harwood Academic Publishers, London.

32. Mellikyan, G.B., Matinyan, N.S., Kocharov, S.L., Arakelian, V.B., Nadareishvili, K.G., and D. Prangishvili, 1991. Electromechanical stability of planar lipid membranes from bipolar lipids of the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Biochemica et Biophysica Acta 1068, 245-248.


31. Bukhrashvili, I., O. Lavrik, A. Levina, G. Nevinsky, and D. Prangishvili. 1990. A comparison of efficiencies of interaction of primers containing bases noncomplementary to templates with DNA polymerases from thermoacidophilic archaebacteria. Molecular Biology (USSR) 24, 370-378.

30. Muskhelishvili, G., M. Karseladze, and D. Prangishvili. 1990. Steroid sensitivity and steroid binding sites of the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Proceedings of the USSR Academy of Sciences 313, 1259-1262.

29. Muskhelishvili, G., M. Karseladze, and D. Prangishvili. 1990. Incorporation of exogenous precursors into the nucleic acids of the extremely thermophilic acidophilic archaebacterium Sulfolobus acidocaldarius. Biochemistry (USSR) 55, 517-524.

28. Mellikyan, G., N. Matinyan, S. Kocharov, V. Arakelian, K. Nadareishvili, and
D. Prangishvili. 1990. Electromechanical properties of planar membranes formed from bipolar lipids of the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Biological Membranes (USSR) 7, 534-539.

27. Prangishvili, D. 1989. Molecular Biology of Archaebacteria. Metsniereba Publishers, Tbilisi.

26. Bukhrashvili, I., D. Chinchaladze, A. Levina, G. Nevinsky, O.Lavrik, and D. Prangishvili. 1989. Comparison of initiating abilities of primers of different lengths and composition in polymerization reactions catalyzed by DNA polymerases from extremely thermophilic archaebacteria. Biochemica et Biophysica Acta 1008, 102-107.


25. Chinchaladze D., D. Prangishvili, A. Scamrov, R. Beabealashvili, N. Dyatkina, and A. Krayevsky. 1989. Nucleoside 5’-triphosphates modified at sugar residues as substrates for DNA polymerase from the thermoacidophilic archaebacterium Sulfolobus acodocaldarius. Biochemica et Biophysica Acta 1008, 113-115.


24. Prangishvili, D. 1988. Molecular organisation of archaebacteria. In Advances in Microbiology, v. 22, pp. 34-70, Nauka Publishers, Moscow.

23. Vashakidze R., and D. Prangishvili, 1987. Sequences poly(dG-dA).poly(dC-dT), poly(dG-dT).poly(dC-dA), poly(dA).poly(dT) and poly(dG).poly(dC) in archae-bacterial genomes. Proceedings of the USSR Academy of Sciences 293, 1243-1245.

22. Vashakidze, R. D. Chinchaladze, and D. Prangishvili. 1987. The genome of the thermoacidophilic archaebacterium Sulfolobus acidocaldarius does not contain repetitive sequences. Molecular Biology Reports 12, 123-126.


21. Vashakidze, R., D. Prangishvili, A. Chkeidze, and D, Chinchaladze. 1987. Structural organization of the genomes of archaebacteria, Part I. Molecular Biology (USSR) 21,696-703.

20. Vashakidze, R., D. Chinchaladze, and D. Prangishvili. 1987. Structural organization of the genomes of archaebacteria, Part II. Molecular Biology (USSR) 21, 1056-1059.

19. Vashakidze, R., and D. Prangishvili. 1987. Simple repetitive sequences in the genomes of archaebacteria. FEBS Letters 216, 217-220.


18. Prangishvili, D., R.Vashakidze, M. Chelidze, D. Chinchaladze, and N. Tsalkalamanidze. 1987. Purification and properties of the restriction endonuclease SuaI from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Biochemistry (USSR) 52, 1043-1050.


17. Chinchaladze D., L. Kachabava, and D. Prangishvili. 1987. A restriction endonuclease ThaI from the thermoacidophilic archaebacterium Thermoplasma acidophilum: purification and properties. Bulletin of the Georgian Academy of Sciences 13, 140-143.

16. Chinchaladze, D., and D. Prangishvili. 1987. Nucleolytic activities of DNA-dependent DNA polymerases of the thermoacidophilic archaebacteria. Bulletin of the Georgian Academy of Sciences, Biol. Series, 13, 57-61.

15. Prangishvili, D., D. Chinchaladze and M. Chelidze. 1987 The thermostability of the enzymes of template-dependent polynucleotide biosynthesis and of the restriction endonucleases of thermoacidophilic archaebacteria. Biothechnology (USSR) 3, 440-446.

14. Prangishvili D. 1986. DNA-dependent DNA polymerases from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Molecular Biology (USSR) 20, 477-488.

13. Prangishvili, D., R. Vashakidze, M. Chelidze, and I. Gabriadze. 1985. A restriction endonuclease SuaI from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. FEBS Letters 192, 57-60.


12. Chinchaladze, D., D. Prangishvili, L. Kachabava, and M. Zaalishvili. 1985. A DNA-dependent DNA polymerase from the thermoacidophilic archaebacterium Thermoplasma acidophilum. Molecular Biology (USSR) 19, 1466-1476.

11. Prangishvili, D. Molecular biology of archaebacteria. 1983. Molecular Biology (USSR) 17, 234-248.


10. Tu, J., D. Prangishvili, H. Huber, G. Widgruber, W. Zillig, and K.O. Stetter. 1982. Taxonomic relations between archaebacteria including 6 novel genera examined by cross hybridization of DNAs and 16S rRNAs. Journal of Molecular Evolution 18, 109-114.

9. Prangishvili, D., W. Zillig, A. Gierl, L. Biessert, and I. Holz. 1982. DNA-dependent RNA polymerases of thermoacidophilic archaebacteria. European Journal of Biochemistry 122, 471-477.

8. Zillig, W., K. O. Stetter, D. Prangishvili, W. Schaefer, S. Wunderl, D. Janekovic, I. Holz and P. Palm. 1982. Desulfurococcaceae, the second family of the extremely thermophilic, anaerobic, sulfur-respiring Thermoproteales. In: Archaebacteria (O. Kandler, ed.), pp. 304-317, Gustav Fischer, Stuttgart - New York.

7. Prangishvili, D., Z. Chidzavadze, and M. Zaalishvili. 1982. The fidelity of DNA replication by calf thymus DNA polymerase. Bulletin of the Georgian Academy of Sciences, Biol. Series 7, 285-288.

6. Prangishvili, D., Z. Chidzavadze, E. Shekikhian, and M. Zaalishvili. 1981. An effect of divalent and monovalent ions on the activity of calf thymus DNA polymerase. Proceedings of the Georgian Academy of Sciences 101, 53-57.

5. Prangishvili, D. and R. Beabealashvili. 1979. Enzymes of template-independent synthesis of polynucleotides. In: Advances in Biological Chemistry, vol. XX, pp. 5-26. Nauka Publishers, Moscow.

2-4. Prangishvili, D., and R. Beabealashvili. Two-component ribonucleotydyl transferase from E.coli:
1975. I. Isolation and purification. Molecular Biology (USSR) 11, 189-202.
1975. II. Enzymatic properties. Molecular Biology (USSR) 11, 203-216.
1978.III. Effect of nucleoside diphosphates on synthesis and pyrophosphorolysis of polyribonucleotides by the enzyme. Biochemica et Biophysica Acta 518, 150-157.


1. Prangishvili, D., and R. Beabealashvili. 1975. Two-component ribonucleotidyl transferase from E.coli. Molecular Biology Reports 2, 129-134.