Publications from the Department of Developmental Biology

2009

GENETIQUE ET EPIGENETIQUE DE LA DROSOPHILE (Drosophila Genetics and Epigenetics) – CNRS : URA 2578 (Christophe ANTONIEWSKI)

Berry B , Deddouche S, Kirschner D, Imler JL, Antoniewski C.  Viral suppressors of RNA silencing hinder exogenous and endogenous small RNA pathways in Drosophila.   PLoS One. 2009 Jun 10;4(6):e5866.

Fagegaltier, D., Bougé, A.-L., Berry, B. , Poisot, E., Sismeiro, O., Coppée, J.-Y., Théodore, L., Voinnet, O., and Antoniewski, C. (2009). The endogenous siRNA pathway is involved in heterochromatin formation in Drosophila. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21258-63.

Quach H, Barreiro LB, Laval G, Zidane N, Patin E, Kidd KK, Kidd JR, Bouchier C, Veuille M, Antoniewski C, Quintana-Murci L. Signatures of purifying and local positive selection in human miRNAs. Am J Hum Genet. 2009 Mar;84(3):316-27.

Saleh, M.-C., Tassetto, M., van Rij, R.P., Goic, B., Gausson, V., Berry, B., Jacquier, C., Antoniewski, C. and Andino, R. Antiviral immunity in Drosophila requires systemic RNA interference spread. Nature. 2009 Feb 8.


UNITE DE GENETIQUE MOLECULAIRE MURINE (Mouse Molecular Genetics) – CNRS : URA 2578 (Philip AVNER)

Billot K, Parizot C, Arrouss I, Mazier D, Debre P, Rogner U, Rebollo A. (2009) Leukemia Research. 2009 Jun 18

Navarro P .  [X inactivation : a direct link with the pluripotent state] Med Sci (Paris). 2009 Nov;25(11):888-90. French. No abstract available.

Navarro P., Avner P . When X-inactivation meets pluripotency: an intimate rendezvous. FEBS Lett. 2009 583,1721-1727.

Navarro P, Chantalat S , Foglio M, Chureau C, Vigneau S, Clerc P, Avner P, Rougeulle C. A role for non-coding Tsix transcription in partitioning chromatin domains within the mouse X-inactivation centre. Epigenetics Chromatin. 2009 Jul 20;2(1):8.

Rougeulle C.    [X inactivation in embryonic stem cells is controlled by pluripotent genes]   Med Sci (Paris). 2009 Mar;25(3):234-5. French. No abstract available.


GENETIQUE MOLECULAIRE DU DEVELOPPEMENT (Molecular Genetics of Development) – CNRS : URA 2578 (Margaret BUCKINGHAM)

Abou-Khalil, R., Le Grand, F., Pallafacchina, G., Valable, S., Authier, F.J., Rudnicki, M.A., Gherardi, R.K., Germain, S., Chretien, F., Sotiropoulos, A., Lafuste, P., Montarras, D., Chazaud, B. (2009). Autocrine and paracrine angiopoietin1/Tie-2 signaling promotes muscle satellite cell self renewal. Cell Stem Cell, 5, 298-309.

Bajolle F, Zaffran S , Losay J, Ou P, Buckingham M, Bonnet D. Conotruncal defects associated with anomalous pulmonary venous connections. Arch Cardiovasc Dis. 2009 Feb;102(2):105-110.

Bryja V, Andersson ER, Schambony A, Esner M, Bryjová L, Biris KK, Hall AC, Kraft B, Cajanek L, Yamaguchi TP, Buckingham M, Arenas E. The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. Mol. Biol. Cell. 2009 Feb;20(3):924-36.

Buckingham M, Vincent SD . Distinct and dynamic myogenic populations in the vertebrate embryo. Curr Opin Genet Dev. 2009 Oct;19(5):444-53.

Crist CG, Buckingham M.    microRNAs gain magnitude in muscle.  Cell Cycle. 2009 Nov 15;8(22):3627-8.

Crist CG, Montarras D, Pallafacchina G, Rocancourt D, Cumano A, Conway SJ, Buckingham M.    Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.    Proc Natl Acad Sci U S A. 2009. 106, 13383-13387.

Daubas, P, Crist, C.G, Bajard, L, Relaix, F, Pecnard, E, Rocancourt, D and Buckingham, M . The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system. Dev. Biol. 327, 71-82 (2009)

Harvey RP, Meilhac SM, Buckingham ME. Landmarks and lineages in the developing heart. Circ Res. 2009 Jun 5;104(11):1235-7. No abstract available.

Lagha, M. , Brunelli, S., Messina, G., Kume, T., Relaix, F., & Buckingham, M.E. (2009). Pax3/7:Foxc2 reciprocal repression in the somite modulates multipotent stem cell fates. Dev Cell. 2009. Dec;17(6):892-9

Lee AS, Kahatapitiya P, Kramer B, Joya JE, Hook J, Liu R, Schevzov G, Alexander IE, McCowage G, Montarras D, Gunning PW, Hardeman EC. Methylguanine DNA methyltransferase-mediated drug resistance-based selective enrichment and engraftment of transplanted stem cells in skeletal muscle. Stem Cells. 2009 May;27(5):1098-108.

Messina G, Sirabella D, Monteverde S, Galvez BG, Tonlorenzi R, Schnapp E, De Angelis L, Brunelli S, Relaix F, Buckingham M, Cossu G.  Skeletal muscle differentiation of embryonic mesoangioblasts requires pax3 activity. Stem Cells. 2009 Jan;27(1):157-64.


MACROPHAGES ET DEVELOPPEMENT DE L’IMMUNITE (Macrophages and Development of Immunity) – CNRS : URA 2578 (Philippe HERBOMEL)

Aggad D, Mazel M, Boudinot P, Mogensen KE, Hamming OJ, Hartmann R, Kotenko S, Herbomel P, Lutfalla G, Levraud JP.  The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains. J Immunol. 2009 Sep 15;183(6):3924-31.

Levraud JP , Disson O, Kissa K, Bonne I, Cossart P, Herbomel P, Lecuit M. Real-time observation of listeria monocytogenes-phagocyte interactions in living zebrafish larvae. Infect Immun. 2009 Sep;77(9):3651-60.
• article selected for Infection & Immunity "Spotlight" (77, 3520)

van der Aa LM, Levraud JP, Yahmi M, Lauret E, Briolat V, Herbomel P, Benmansour A, Boudinot P. A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish. BMC Biol. 2009 Feb 5;7:7.
• with Comment by L. Du Pasquier (2009). Fish ’n’ TRIMs. J. Biol. 8, 50.


CENTRE D’INGENIERIE GENETIQUE MURINE (Mouse Genetics Engineering Center) (Francina LANGA VIVES)

Alves NL, Richard-Le Goff O, Huntington ND, Sousa AP, Ribeiro VSG, Bordack A, Langa Vives F, Peduto L, Chidgey A, Cumano A, Boyd R, Eberl G, Di Santo JP.  Characterization of the thymic IL-7 niche in vivo.  Proc. Natl. Acad. Sci. 2009. 106(5):1512-1517

Mashimo T, Hadjebi O, Amair-Pinedo F, Tsurumi T, Langa F, Serikawa T, Sotelo C, Guénet JL, Rosa JL.   Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase.    PLoS Genet.  2009.  5(12):e1000784.


GENETIQUE DU DEVELOPPEMENT HUMAIN (Human Developmental Genetics) (Kenneth McELREAVEY)

Bashamboo A, Ravel C, Brauner R, McElreavey K. [NR5A1 and ovarian failure] Med Sci (Paris). 2009 Oct;25(10):809-13.

Benkhalifa M, Montjean D, Cohen-Bacrie P, Ménézo Y. Imprinting: RNA expression for homocysteine recycling in the human oocyte. Fertil Steril. 2009 Apr 8.

Dessolle L, Biau DJ, de Larouzière V, Ravel C, Antoine JM, Daraï E, Mandelbaum J. Learning curve of vitrification assessed by cumulative summation test for learning curve (LC-CUSUM). Fertil Steril. 2009 92:943-5

Imken L , Rouba H, El Houate B, Louanjli N, Barakat A, Chafik A, McElreavey K. Mutations in the protamine locus: association with spermatogenic failure? Mol Hum Reprod. 2009. 15:733-8.

Lourenço D , Brauner R, Lin L, De Perdigo A, Weryha G, Muresan M, Boudjenah R, Guerra-Junior G, Maciel-Guerra AT, Achermann JC, McElreavey K, Bashamboo A. Mutations in NR5A1 associated with ovarian insufficiency. N Engl J Med. 2009 Mar 19;360(12):1200-10.

Ravel C , Lakhal B, Elghezal H, Braham R, Saad A, Bashamboo A, Siffroi JP, McElreavey K, Christin-Maitre S. Novel human pathological mutations. Gene symbol: SRY. Disease: XY sex reversal. Hum Genet. 2009 Aug;126(2):333. No abstract available.

Ravel C, Chantot-Bastaraud S, Chalmey C , Barreiro L, Aknin-Seifer I, Pfeffer J, Berthaut I, Mathieu EE, Mandelbaum J, Siffroi JP, McElreavey K, Bashamboo A. Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts. PLoS One. 2009 Aug 6;4(8):e6540.

Ravel C, Lorenço D , Dessolle L, Mandelbaum J, McElreavey K, Darai E, Siffroi JP. Mutational analysis of the WNT gene family in women with Mayer-Rokitansky-Kuster-Hauser syndrome. Fertil Steril. 2009 Apr;91(4 Suppl):1604-7.

Vinci G , Brauner R, Tar A, Rouba H, Sheth J, Sheth F, Ravel C, McElreavey K, Bashamboo A. Mutations in the TSPYL1 gene associated with 46,XY DSD and male infertility. Fertil Steril. 2009. 92:1347-50


ANIMALERIE CENTRALE (Mouse Facility) (Xavier MONTAGUTELLI)

Berard M, Medaille C, Simon M, Serre S, Pritchett-Corning K, Dangles-Marie V. Ralstonia pickettii-induced ataxia in immunodeficient mice. Comp Med. 2009 Apr;59(2):187-91.


REGULATION EPIGENETIQUE (Epigenetic regulation) – CNRS : URA 2578 (Christian MUCHARDT)

Bierne H, Tham TN, Batsché E, Dumay A, Leguillou M, Kernéis-Golsteyn S, Regnault B, Seeler JS, Muchardt C, Feunteun J, Cossart P. Human BAHD1 promotes heterochromatic gene silencing. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13826-31.

Boukarabila H, Saurin AJ, Batsché E, Mossadegh N, van Lohuizen M, Otte AP, Pradel J, Muchardt C, Sieweke M, Duprez E.  The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation.  Genes Dev. 2009 May 15;23(10):1195-206.

Bourgo RJ, Siddiqui H, Fox S, Solomon D, Sansam CG, Yaniv M, Muchardt C, Metzger D, Chambon P, Roberts CW, Knudsen ES.   SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.   Mol Biol Cell. 2009 Jul;20(14):3192-9.

Koga M, Ishiguro H, Yazaki S, Horiuchi Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Muchardt C, Yaniv M, Arinami T. Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. Hum Mol Genet. 2009 Jul 1;18(13):2483-94.

Lavigne M, Eskeland R, Azebi S, Saint-André V, Jang SM, Batsché E, Fan HY, Kingston RE, Imhof A, Muchardt C. Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression. PLoS Genet. 2009 Dec;5(12):e1000769.

Raymond B, Batsche E, Boutillon F, Wu YZ, Leduc D, Balloy V, Raoust E, Muchardt C, Goossens PL, Touqui L.  Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification. PLoS Pathog. 2009 Apr;5(4):e1000359.


BIOLOGIE MOLECULAIRE DU DEVELOPPEMENT (Molecular Biology of Development) – CNRS : URA 2578 (Jean-François NICOLAS)

Petit AC , Nicolas JF.  Large-scale clonal analysis reveals unexpected complexity in surface ectoderm morphogenesis.  PLoS One. 2009. 4(2):e4353

Tsakiridis A, Tzouanacou E, Rahman A, Colby D, Axton R, Chambers I, Wilson V, Forrester L, Brickman JM.   Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells.   Nucleic Acids Res. 2009 Aug 19.

Tzouanacou E , Wegener A, Wymeersch FJ, Wilson V, Nicolas JF.   Redefining the progression of lineage segregations during mammalian embryogenesis by clonal analysis.   Dev Cell. 2009 Sep;17(3):365-76.


GENETIQUE FONCTIONNELLE DE LA SOURIS (Mouse Functional Genetics) – CNRS : URA 2578 - INRA: USC 2026 (Jean-Jacques PANTHIER)

Ahmed AU, Moulin M, Coumailleau F, Wong WW, Miasari M, Carter H, Silke J, Cohen-Tannoudji M, Vince JE, Vaux DL. CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha. Curr Biol. 2009 Jan 13;19(1):R15-7; author reply R17-9.

Boumahrou, N., Andrei, S., Miranda, G., Henry, C., Panthier, J.-J., Martin, P., and Bellier, S.  The major protein fraction of mouse milk revisited using proven proteomic tools.  J. Physiol. Pharmacol.  2009. 60:113-118.

Burgio G, Baylac M, Heyer E, Montagutelli X. Genetic analysis of skull shape variation and morphological integration in the mouse using interspecific recombinant congenic strains between C57BL/6 and mice of the mus spretus species. Evolution. 2009. 63:2668-2686

Dejager L, Libert C, Montagutelli X. Thirty years of Mus spretus: a promising future. Trends Genet. 2009 May;25(5):234-41.

Jory, A., Le Roux, I., Gayraud-Morel, B., Rocheteau, P ., Cohen-Tannoudji, M., Cumano, A., and Tajbakhsh, S. (2009). Numb Promotes an Increase in Skeletal Muscle Progenitor Cells in the Embryonic Somite. Stem Cells 27:2769-2780.

Laissue P, Burgio G, l’Hôte D, Renault G, Marchiol-Fournigault C, Fradelizi D, Fellous M, Serres C, Montagutelli X, Monget P, Vaiman D. Identification of Quantitative Trait Loci responsible for embryonic lethality in mice assessed by ultrasonography. Int J Dev Biol. 2009;53(4):623-9.

Monet-Leprêtre M, Bardot B, Lemaire B, Domenga V, Godin O, Dichgans M, Tournier-Lasserve E, Cohen-Tannoudji M, Chabriat H, Joutel A. Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain. Brain. 2009. 132 :1601-1612

Santos J, González-Sánchez L, Matabuena-Deyzaguirre M, Villa-Morales M, Cozar P, López-Nieva P, Fernández-Navarro P, Fresno M, Díaz-Muñoz MD, Guenet JL, Montagutelli X, Fernández-Piqueras J. A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion. Cancer Res. 2009 Mar 15;69(6):2577-87.



EXPRESSION GENIQUE, DEVELOPPEMENT ET MALADIES (Gene expression, development and disease) – CNRS : URA 2578 (Marco PONTOGLIO)
• depuis le 30-09-2009, l’équipe est maintenant à l’I. Cochin (Inserm-UPMC-CNRS: UMR8104) - New address : Institut Cochin, Paris

Fischer E, Pontoglio M.   HNF1beta and defective nephrogenesis: a role for interacting partners?  Kidney Int. 2008 Jul;74(2):210-7

Gong Y, Ma Z, Patel V, Fischer E, Hiesberger T, Pontoglio M, Igarashi P.   HNF-1beta regulates transcription of the PKD modifier gene Kif12.   J Am Soc Nephrol. 2009 Jan;20(1):41-7.

Pongratz RL, Kibbey RG, Kirkpatrick CL, Zhao X, Pontoglio M, Yaniv M, Wollheim CB, Shulman GI, Cline GW.  Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1{alpha} and in HNF-1{alpha}-deficient islets.  J Biol Chem. 2009 Jun 19;284(25):16808-21.

Ratelade, J., Arrondel, C., Hamard, G., Garbay, S., Harvey, S., Biebuyck, N., Schulz, H., Hastie, N., Pontoglio, M., Gubler, M.C., Antignac, C., Heidet, L.  A Murine Model of Denys-Drash Syndrome Reveals Novel Transcriptional Targets of Wt1 in Podocytes.  Hum Mol Genet (2009).

Vallania F, Schiavone D, Dewilde S, Pupo E, Garbay S, Calogero R, Pontoglio M, Provero P, Poli V. Genome-wide discovery of functional transcription factor binding sites by comparative genomics: the case of Stat3. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5117-22.

Verdeguer, F. , Le Corre, S., Fischer, E., Callens, C., Doyen A., Garbay, S., Igarashi, P., Terzi, F., Pontoglio, M. A mitotic Transcriptional Switch in Polycystic Kidney Disease.   Nat Med. 2010 Jan;16(1):106-10. Epub 2009 Dec 6.


GENETIQUE MOLECULAIRE DE LA MORPHOGENESE (Morphogenesis Molecular Genetics) – CNRS : URA 2578 (Benoît ROBERT)

Lallemand Y, Bensoussan V, Cloment CS, Robert B.   Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb. Dev Biol. 2009 Jul 15;331(2):189-98.


GENETIQUE DU DEVELOPPEMENT DE LA DROSOPHILE (Drosophila Developmental Genetics) CNRS : URA 2578 (François SCHWEISGUTH)

Chanet S, Vodovar N, Mayau V, Schweisguth F . Genome Engineering-based Analysis of Bearded Family Genes Reveals Both Functional Redundancy and a Non-essential Function in Lateral Inhibition in Drosophila. Genetics. 2009. 182, 1101-1108

del Alamo D. and F. Schweisguth Dispatch : Notch signalling: receptor cis-inhibition to achieve directionality. Current Biology. 2009. 19, R683-4

Gomes J.-E., Corado M. S., Schweisguth F., Van Gogh and frizzled act redundantly in the Drosophila sensory organ precursor cell to orient its asymmetric division. PLoSOne. 2009. 4(2) : e4485

Schweisguth F . News & Views : When you are Dishevelled, fat is good and acid is bad! Nat  Cell Biol. 2009. 11(3):237-9.


CELLULES SOUCHES ET DEVELOPPEMENT (Stem Cells and Development) – CNRS : URA 2578 (Shahragim TAJBAKHSH)

Castets P, Maugenre S, Gartioux C, Rederstorff M, Krol A, Lescure A, Tajbakhsh S, Allamand V, Guicheney P.   Selenoprotein N is dynamically expressed during mouse development and detected early in muscle precursors.  BMC Dev Biol. 2009 Aug 22;9:46.

Jory A, Le Roux I, Gayraud-Morel B, Rocheteau P , Cohen-Tannoudji M, Cumano A, Tajbakhsh S.   Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite. Stem Cells. 2009 Nov;27(11):2769-80.

Gayraud-Morel B, Chrétien F, Tajbakhsh S.    Skeletal muscle as a paradigm for regenerative biology and medicine.  Regen Med. 2009 Mar;4(2):293-319. Review

Sambasivan R, Gayraud-Morel B, Dumas G, Cimper C, Paisant S, Kelly R, Tajbakhsh S.    Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates.  Dev Cell. 2009 Jun;16(6):810-21.

Shinin V, Gayraud-Morel B, Tajbakhsh S.    Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells.   In: Stem Cells in Regenerative Medicine. Series: Methods in Molecular Biology (Humana Press, USA) 482: 295-317.

Shoji H, Deltour L, Nakamura T, Tajbakhsh S.   Poirier F. Expression pattern and role of Galectin1 during early mouse myogenesis.   Dev Growth Differ. 2009 51(7):607-15.

Tajbakhsh S . Stem cell: what’s in a name?   Nature Reports Stem Cells. 2009. June 25.

Tajbakhsh S .  Skeletal muscle stem cells in developmental versus regenerative myogenesis. J Intern Med. 2009. 266(4):372-89.

Tajbakhsh S . Gonzalez C.  Biased segregation of DNA and centrosomes: moving together or drifting apart?   Nature Reviews Molecular & Cellular Biology. .2009. 10(11):804-10.