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Scientific Program

Thursday 22 April 2010

Session 1: Neurotoxic proteins and neurodegeneration

Chair: Gerry Melino (Medical Research Council, Leicester, UK)

9:00 am - 9:15 am Marie-Lise Gougeon & Guido Kroemer “Welcome and Grand Opening” 9:15 am - 9:45 am David Rubinsztein (University of Cambridge, Cambridge, UK) “Autophagy, a guardian against neurodegeneration” 9:45 am - 10:15 am Olaf Riess (University of Tuebingen, Germany) “Transgenic animal models of neurodegenerative diseases” 10:15 am - 10:45 am Frederic Saudou (Institut Curie, Orsay, France) “Molecular and cellular pathogenesis of Huntington disease” 10:45 am - 11:15 am: Coffee break (with exhibition viewing)

Session 2 : Signaling for the avoidance of cell death

Chair: OLaf Riess (University of Tuebingen, Germany)

11:15 am - 11:45 am Julia Ring (University of Graz, Austria) “A mechanism for Spartin-mediated cytotoxicity” 11:45 am - 12:15 am Guido Kroemer (INSERM, Villejuif, France) “Autophagy in stress adaptation, avoidance of cell death and longevity” 12:15 am - 12:45 am Jürg Bähler (Sanger Institute, Cambridge, UK) “Genome regulation in response to stress in fission yeast” 12:45 am - 1:00 pm : Oral presentation Nathaniel Szewczyk (University of Nottingham, UK) “Integrated control of muscle protein degradation in C. elegans” 1.00 pm – 2:30 pm : Lunch and poster viewing

Session 3 : Cell stress and cell death

Chair: Alexis  Brice (University of Paris 6, Paris, France

2:30 pm - 3:00 pm Lorenzo Galluzzi “Systems biology of the cisplatin response in non-small cell lung cancer” 3:00 pm - 3:15 pm : Oral presentation He Liu (University of Bern, Switzerland) “Down regulation of autophagy related gene 5 (Atg5) in malignant melanoma contributes to melanoma tumorigenesis” 3:15 pm - 3:45 pm Gerry Melino (Medical Research Council, Leicester, UK) “P73, an ancestral members of the p53 family, is involved in neuronal development via miR-34a” 3:45 pm - 4: 15 pm Peter Vandenabeele (University of Ghent, Belgium) “TNF – induced necrosis, multiple regulation of RIP1 kinase activity” 4.15 pm – 4.45 pm: Coffee-break (with exhibition viewing) 4:45 pm - 5:15 pm Nektarios Tavernarakis (Institute of Molecular Biology and Biotechnology, Heraklion, Greece) “Heat shock proteins and necrosis” 5:15 pm - 5:45 pm Guillermo Marino (University of Oviedo, Spain) "The degradome and its pathophysiological impact: the vortex of vertigo". 5:45 pm - 6:00 pm: Oral Presentation Francois Paquet-Durand (University of Tuebingen, Germany) "The role of Histone Deacetylase (HDAC) activity during photoreceptor cell death" 6:00 pm - 6:30 pm Stefan Wiemann (German Cancer Research Center, Heidelberg, Germany) “Human kinome screen with xCELLigence technology uncovers the dynamics of RNAi phenotypes” Opening Cocktail