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Scientific Program

Friday, April  23th,  2010

Session 4 : Sophisticated self-destructive pathways

Chair: Laurence Zitvogel (Institut Gustave Roussy, France)

8.45 am - 9.15 am : Peter H. Krammer (DKFZ, Heidelberg, Germany) "Life and death: a systems biology approach to CD95 signaling" 9:15 am - 9:45 am Eric Solary (Institut Gustave Roussy, Villejuif, France) “A differentiating function for caspase in specific hematopoietic lineages” 9:45 am - 10:15 am Seamus Martin (Trinity College, Dublin, Ireland) “Bcl-2 family proteins as modulators of Oncogenic Ras-induced cell death” 10:15 am - 10:45 am Mauro Piacentini (University of Rome-Tor Vergata, Rome, Italy) “Ambra-1: A key player in the regulation of autophagy in mammals”

Session 5: Cancer cell death pathways

Chair: Peter H. Krammer (DKFZ, Heidelberg, Germany)

11 :15 am - 11 :45 am Hervé Fridman (Centre de Recherche des Cordeliers, Paris, France) "Triggering through Toll-Like receptors induces human lung tumor cell resistance to chemotherapy" 11:45 am - 12:15 am Boris Zhivotovsky (Karolinska Hospital, Stockholm, Sweden) “Global gene analysis reveals Ephrin B3 as a potential radiosensitizing target in Non-small cell lung cancer cells” 12:15 am - 12:45 am Laurence Zitvogel (Institut Gustave Roussy, Villejuif, France) “Exploring the contribution of the immune system to conventional and targeted anticancer therapies” 12:45 am - 1:15 pm Cornelies Melief (Leiden University, Leiden, The Netherlands) “Successful immunotherapy of human neoplasia” 1:15 pm - 2:45 pm : Lunch and poster viewing

Session 6 : Infection: danger, stress and death

Chair: Peter Vandenabeele (University of Ghent, Belgium)

2:45 pm - 3:15 pm Philippe Sansonetti (Institut Pasteur, Paris, France) “Invasion of the intestinal epithelium by Shigella : the Yin and the Yang of innate immunity” 3:15 pm - 3:45 pm Hans-Uwe Simon (University of Bern, Switzerland) “Caspase -dependent and -independent mechanisms of neutrophil death” 3:45 pm - 4:15 pm Marie-Lise Gougeon (Institut Pasteur, Paris, France) “HIV: death, danger and immunity” 4:15 pm-4:45 pm : Coffee-break (with exhibition viewing)

Session 7 : Aging, degeneration and cell death

Chair: Hervé Fridman (Centre de Recherche des  Cordeliers, Paris, France)

4:45 pm - 5:15 pm Frank Madeo (University of Graz, Austria) “Programmed cell death in yeast : subroutines, mechanisms and purposes” 5:15 pm - 5:30 pm – Oral Presentation Gloria Villalpando Rodriguez (INSERM U872, Paris, France) “Lysosome permeabilisation in apoptotic-like cell death” 5:30 pm - 5:45 pm – Oral Presentation Walter Malorni (Istituto Superiore di Sanita, Rome, Italy) “Xeno-cannibalism and self-cannibalism (autophagy): related or unrelated phenomena? The case of lymphocytes from centenarians” 5:45 pm - 6:15 pm Alexis Brice (University of Paris 6, France) “Parkinson's disease: from genes to insight into mechanisms” Concluding remarks Departure for the Gala Dinner (Cruise on the Seine)