Scientific program
PRELIMINARY PROGRAM
Tuesday, May 14, 2013 , Afternoon
2:00-2:15 Welcoming remarks: Stuart EDELSTEIN, Alice DAUTRY
2:15-3:00 Keynote lecture: Jean-Pierre CHANGEUX “Historical Perspective”
Plenary Session: PROTEIN DYNAMICS
3:00-3:30 Jean-Marie LEHN* “Towards Adaptive Chemistry: Constitutional and Allosteric Dynamics”
3:30-4:00 Kurt WüTHRICH* “Allostery in Hemoglobin and GPCRs Viewed by NMR”
4:00-4:30 Coffee break
4:30-5:00 Peter WRIGHT “Exploring protein energy landscapes by NMR relaxation”
5:00-5:30 Martin KARPLUS, TBA
5:30-6:00 Dennis BRAY “Propagation of allosteric states in large protein assemblies”
6:00-6:30 Charalampos KALODIMOS" Allosteric interactions mediated by internal dynamics"
6:30-7:00 2 short talks
7:00-8:30 Welcoming cocktail
Wednesday, May 15, Morning
Plenary Session: ALLOSTERIC ENZYMES
9:00-9:30 John WALKER*, TBA
9:30-10:00 Avram HERSHKO*, TBA
10:00-10:30 Susan TAYLOR “PKA: Assembly of Dynamic Macromolecular Signaling Complexes”
10:30-11:00 Coffee break
11:00-11:30 Wendell LIM “Modular allosteric signaling proteins”
11:30-12:00 Wolfgang BAUMEISTER “The 26S proteasome: A molecular machine designed for controlled proteolysis”
12:00-12:30 2 short talks- to be selected
12:30-2:00 Lunch and poster viewing
Afternoon
Plenary Session: CHAPERONS AND MOTORS
2:00-2:30 Arthur HORWICH “Allosteric movements drive protein folding by GroEL/GroES”
2:30-3:00 Anne HOUDUSSE “Allostery in molecular motors convert chemical energy into force production”
3:00-3:30 Helen SAIBIL, TBA
3:30-4:00 Coffee break
Plenary Session: VIRUSES
4:00-4:30 Felix REY, TBA
4:30-5:00 Jack JOHNSON “Biophysical studies of virus maturation reveals allosteric behavior of capsid subunits”
5:00-5:30 Núria VERDAGUER “Structural Dynamics of the Vault Ribonucleoprotein Particle:
A versatile Signal Regulation and Transport Platform”
5:30-7:00 6 Short talks-to be selected
7:00-9:00 Poster session along with wine and cheese party
Thursday, May 16, Morning
Plenary Session: RECEPTOR ION CHANNELS
9:00-9:30 Pierre-Jean CORRINGER TBA
9:30-10:00 Stuart EDELSTEIN TBA
10:00-10:30 Karl DEISSEROTH (Optogenetics)
10:30-11:00 Coffee break
11:00-11:30 Anthony AUERBACH “Design and control of acetylcholine receptor-channels”
11:30-12:00 Lucia SIVILOTTI “Single molecule experimental insights into the activation of ligand-gated channels”
12:00-12:30 2 Short talks
12:30-2:00 Lunch and poster viewing
Afternoon
Plenary Session: MEMBRANE PROTEINS
2:00-2:30 Brian KOBILKA* “Structural insights into allosteric regulation of G protein coupled receptors”
2:30-3:00 Heidi HAMM “Dynamics of G protein activation by GPCRs”
3:00-3:30 Jean Philippe PIN “Metabotropic glutamate receptors: allosteric machines tuning synaptic activity”
3:30-4:00 Joseph SCHLESSINGER “Cell Signaling by Receptor Tyrosine Kinases; from basic principles to cancer therapy”
4:00-4:30 Coffee break
4:30-5:00 John KURIYAN, TBA
5:00-5:30 Gunnar VON HEIJNE, TBA
5:30-6:00 Nicolas REYES “Excitatory Amino Acid Transporters: trimeric proteins with intra-subunit allostery”
7:15 Conference dinner "Maison de la Chimie" Paris
Friday, May 17, morning
Plenary Session: REPLICATION AND GENE EXPRESSION
9:00-9:30 Michael BOTCHAN “Controlling the switch to S Phase in the cell cycle: Activation of the MCM helicase”
9:30-10:00 Mitchell LEWIS, TBA
10:00-10:30 Daniella RHODES “Chromatin structure and its regulation”
10:30-11:00 Coffee break
11:00-11:30 Dino MORAS “Allosteric control of coactivator recruitment by Nuclear Hormone Receptors”
11:30-12:30 4 short talks
12:30-2:00 Lunch and poster viewing
Afternoon
Plenary Session: RIBOSOMES, RNA, AND RIBO-SWITCHES
2:00-2:30 Venki RAMAKRISHNAN*, TBA
2:30-3:00 Ada YONATH*, TBA
3:00-3:30 Jennifer A: DOUDNA “The helical handshake: Understanding how RNA structure affects regulatory RNA processing”
3:30-4:00 Poul NISSEN, TBA
4:00-4:30 Coffee break
4:30-5:00 Marat YUSUPOV “Structure of bacterial and yeast ribosome”
5:00-5:30 Elena CONTI “Allosteric regulation in the multi-subunit RNA exosome complex”
5:30- 6:15 3 short talks
6:15-7:00 Rob PHILIPS “Closing remarks”
* Nobel Prize winners