Proteopole / Crystallography / Publications / Publications 2014

Publications 2014

A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase.

Giganti D, Bouillon A, Tawk L, Robert F, Martinez M, Crublet E, Weber P, Girard-Blanc C, Petres S, Haouz A, Hernandez JF, Mercereau-Puijalon O, Alzari PM, Barale JC.
Nat Commun
. 2014 Sep 10

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities.

Amiable C, Paoletti J, Haouz A, Padilla A, Labesse G, Kaminski PA, Pochet S.
Eur J Med Chem
. 2014 Oct 6

Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase.

Cavaliere P, Levi-Acobas F, Mayer C, Saul F, England P, Weber P, Raynal B, Monteil V, Bellalou J, Haouz A, Norel F.
Biochem J
. 2014 Jul 24

Structural and enzymatic insights into Lambda glutathione transferases from Populus trichocarpa, monomeric enzymes constituting an early divergent class specific to terrestrial plants.

Lallement PA, Meux E, Gualberto JM, Prosper P, Didierjean C, Saul F, Haouz A, Rouhier N, Hecker A.
Biochem J
. 2014 Aug 15

Structural basis of eukaryotic cell-cell fusion.

Pérez-Vargas J, Krey T, Valansi C, Avinoam O, Haouz A, Jamin M, Raveh-Barak H, Podbilewicz B, Rey FA.
. 2014 Apr 10

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.

Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M.
Proc Natl Acad Sci U S A
. 2014 Jan 21