Theme de la conférence
Programme scientifique
Conférence EWGLI
(pour les collaborateurs)
Programme social
Inscription en ligne ouverte
Appel à résumés
Grants pour les étudiants
Informations pratiques

Dates limites

Tarifs préférentiels :
24 juillet 2009

Soumission des résumés :
24 juillet 2009

Demande de grants pour le voyage des étuduants :
24 juillet 2009

Logo design:

programme scientifique

Mardi 13 octobre 2009

10h00-16h00 Ewgli meeting for Ewgli collaborators only, related to business aspects of the EWGLINET network and the transfer of the scheme to ECDC
14h00-17h30 Accueil participants
17h30-18h00 Discours de bienvenue
Tony Pugsley, Senior Executive-Vice President for Scientific Affaire, Institut Pasteur, Paris, France
Carmen Buchrieser, Institut Pasteur, Paris, France
Session d'ouverture
Modérateur : Nicholas P. Cianciotto, Northwestern University Medical School,
  Barry Fields, Center of Disease Control, Atlanta, USA
Environmental approaches to the prevention of legionellosis
  Carol Joseph, Health Protection Agency, London, UK
Legionnaires' disease in Europe 1995 - 2008: Trends and challenges
  Jörg Hacker, Robert Koch Institut, Berlin, Germany
Legionella. A model organism for Genomics and Cellular Microbiology
19h30 Cocktail de Bienvenue à l' Institut Pasteur

Mercredi 14 octobre 2009

Session 1: Epidemiology and Clinical aspects a) disease, diagnosis and treatment

Modérateur : Didier Che, Institut de Veille Sanitaire, Saint-Maurice, France

8h30-9h00 Miguel Sabria, University of Barcelona, Spain
Clinical aspects of Legionnaires´Disease
9h00-9h30 Paul H Edelstein, University of Pennsylvania, Philadelphia, USA
Antimicrobial therapy for Legionnaires' disease, still in need of improvement
9h30-9h45 Maria Luisa Pedro-Botet, Spain
Legionella pneumonia (LP) in immunosuppressed (IS) patients
9h45-10h00 Frances Graham, New Zealand
Changing Epidemiologic Trends of Legionellosis in New Zealand, 1979 - 2008
10h00-10h15 Lauri Hicks, USA
Travel-Associated Legionnaires' Disease Surveillance in the United States, 25-28
10h15-10h45 Pause-café
Session 2: Clinical aspects b) detection and subtyping
Chair: Jaana Kusnetsov, National Public Health Institute, Kuopio, Finland
10h45-11h15 Christian Lück, University Dresden, Germany
Microbiological diagnostic methods for the detection of Legionella infections
11h15-11h45 Timothy G. Harrison, Health Protection Agency, London, UK
Legionella pneumophila DNA sequence-based typing: progress, pitfalls and perspectives.
11h45-12h00 Patrick Yang, USA
Evaluation of a fully integrated point-of-testing system for the detection of viable Legionella pneumophila
12h00-12h15 Valeria Gaia, Switzerland
MALDI-TOF MS based protein mass fingerprinting: a rapid and reliable method for the identification of Legionella spp.
12h15-12h30 Jonas Lundström, Sweden
An improved and rapid sequence-based method for typing of Legionella pneumophila.
12h30-14h00 Déjeuner à l' Institut Pasteur
14h00-15h30 Session Poster
Session 3: Host - Microbe interactions: a) secretion systems and their substrates
Modérateur : Craig Roy, Yale University, USA
15h30-15h55 Nicholas Cianciotto, North Western University, Chicago, USA
Type II protein secretion, siderophores, and pigment and what they mean for Legionella ecology and pathogenesis
15h55-16h20 Joseph Vogel, Washington University, St Louis, USA
The Legionella Dot/Icm type IVB secretion system
16h20-16h45 Antje Flieger, Robert Koch Institut, Berlin, Germany
Legionella pneumophila phospholipases and their mode of secretion
16h45-17h00 Li Xu Luo, USA
Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila effector
17h00-17h15 Mariella Lomma, France
Legionella pneumophila infections involve bacterial F-box proteins
17h15-17h45 Pause-café
Session 4: Host - Microbe interactions:         
b) metabolism and virulence
Modérateur : Philippe Glaser, Institut Pasteur
17h45-18h15 Paul Hoffman, University of Virginia, Charlottesville, USA
The Legionella pneumophila Developmental Cycle: Role in Survival and Pathogenesis
18h15-18h45 Michele Swanson, Michigan University, USA
Legionella pneumophila virulence as a response to starvation
18h45-19h00 Yury Belyi, Russia
Cytotoxic glucosyltransferases of Legionella pneumophila
19h15-20h30 “Wine and cheese” party

Jeudi 15 octobre 2009

Session 5: Immunology and host susceptibility
Modérateur : Ralph Isberg, Tufts University, Boston, USA
9h00-9h30 Tom Hawn, University Washington, Seattle, USA
Genetic variation & the pulmonary innate immune response to Legionella
9h30-9h45 Catarina Nogueira, USA
Dendritic cells rapidly undergo apoptosis to limit intracellular replication of Legionella pneumophila
9h45-10h00 Tatiana Silveira, Brazil
Pore formation is an Nlrc4/Ipaf inflammasome-dependent host cell response against virulent Legionella species that express flagellin
10h00-10h15 Juliane Lippmann, Germany
Type I IFNs mediate innate intracellular defense to Legionella pneumophila
10h15-10h45 Pause-café
Session 6: Microbe - Environment interactions:        
a) cell biology, protozoa, biofilms
Modérateur : Agnes Ullmann, Institut Pasteur
10h45-11h15 Michael Steinert, University Braunschweig, Germany
Proteomic and functional characterization of outer membrane vesicles and Legionella-containing phagosomes
11h15-11h45 Hubert Hilbi, University of Zürich, Zürich, Switzerland
Signals produced and exploited by Legionella
11h45-12h15 Howard A. Shuman, Columbia University, New York, USA
Host determinants of Legionella infection
12h15-12h30 Sophie Pécastaings, France
A new method of producing Legionella pneumophila biofilms in a minimal medium
12h30-12h45 Rafael A. Garduno, Canada
Mature infectious forms (MIFs) and MIF-pellets as factors in the transmission of Legionnaires' disease
12h45-14h00 Déjeuner à l' Institut Pasteur
14h00-15h30 Session Poster
Session 7: Microbe - Environment interactions:
b) detection in natural and artificial reservoirs - survival, persistence
Modérateur : Yann Héchard, Université de Poitiers, France
15h30-16h00 Paola Borella, Modena University, Italy
Risk factors for Legionella contamination and persistence in potential sources of infection
16h00-16h30 Shin-ichi Yoshida, Kyushu University, Fukuoka, Japan
Legionella physiology in the environment
16h30-16h45 Rinske Valster, Netherlands
Detection of hosts for Legionella pneumophila in freshwater by enrichment of free-living protozoa in a biofilm-batch system
16h45-17h00 Sharon G. Berk, USA
Long-term survival of novel amoeba-associated bacteria compared with Legionella pneumophila under conditions of hydration and desiccation
17h00-17h30 Pause-café

Session 8: Legionella prevention and control

Modérateur : Maria Luisa Ricci, Istituto Superiore di Sanita, Rome, Italy
17h30-18h00 Katherine Ricketts, Health Protection Agency, London, UK
Travel associated Legionnaires' disease in Europe 2008: reporting and response
18h00-18h30 Janet Stout, Special pathogens Unit, Pittsburg, USA
Legionella and the Conundrum of Low Risk Buildings: A Very Modest Proposal
18h30-18h45 John V. Lee, UK
An international trial of quantitative PCR for monitoring Legionella in artificial water systems
19h30 Dîner de gala

Vendredi 16 octobre 2009

Session 9: Epidemiology: a) nosocomial infections and Legionella control in hospitals
Modérateur : Paul H. Edelstein, University of Pennsylvania Medical Center,
Philadelphia, USA
8h30-9h00 Loreen Herwaldt, University of Iowa Hospital, USA
Decontamination of Hospital Water Supplies: A Review of the Literature and the University of Iowa's Experience
9h00-9h30 Jérôme Etienne, University Lyon, France
Nosocomial infections, Legionella strain characterization and host-related risk factors
9h30-9h45 Sebastian Crespi, Spain
Legionellosis Prevention Guidelines: Better, but Not Well
9h45-10h00 Claressa Lucas, USA
The impact of monochloramine introduction on Legionella colonization in a hospital potable water system.
10h00-10h15 Susanne Surman-Lee, UK
Lessons learnt from investigating hospital-acquired legionellosis and the remedial actions in England.
10h15-10h45 Pause-café
Session 10: Epidemiology:
b) outbreaks and population genetics and taxonomy
Modérateur : Carmen Pelaz, Instituto de Salud Carlos III, Madrid, Spain
10h45-11h15 Antoni Plasencia, Public Health Catalonia, Spain
Managing public health crises: from legionellosis to pandemic influenz
11h15-11h45 Rod Ratcliff, Infectious disease laboratories, Adelaide, Australia
Ecological diversity within Legionella
11h45-12h00 Mireia Coscollá, Spain
Multiple Legionella strains infection detected by sequence analysis directly from respiratory samples
12h00-12h15 Igor S. Tartakovskiy, Russia
From large community outbreak in Verhnaya Pyshma to effective prevention of legionellosis in Russia.
12h15-12h30 Joana Costa, Portugal
Molecular evolution of dotA gene in Legionella pneumophila: contribution of natural environmental isolates.
12h30-14h00 Déjeuner à l' Institut Pasteur
14h00-15h30 Session Poster
Session 11: Genomics and Comparative genomics
Modérateur : Howard Shuman, Columbia University, New York, USA
15h30-16h00 Carmen Buchrieser, Institut Pasteur, Paris, France
Legionella pneumophila and Legionella longbeachae pathogenesis: new insights gained form comparative and functional genomics
16h00-16h15 Brian Shelton, USA
Polymorphic loci in Legionella pneumophila serogroup 1
16h15-16h30 Olga Shevchuk, Germany
Proteomic analysis of a Legionella-containing phagosome in Dictyostelium
16h30-16h45 Ivan Moszer, France
Genome re-annotation and web resources for Legionella pneumophila species
16h45-17h15 Pause-café
Session 12: Functional genomics
Modérateur : Michele Swanson, University of Michigan Medical Center, Ann Arbor, USA
17h15-17h45 Elisabeth Hartland, University Melbourne, Australia
Hidden protein treasures revealed in the Legionella genome
17h45-18h00 Frank Schuren, Netherlands
Epidemiological genome analysis of a large Dutch Legionella pneumophila strain collection identifies five markers highly correlated with pathogenic strains
18h00-18h15 Tamara O'Connor, USA
Solving functional redundancy amongst effectors of the bacterial pathogen, Legionella pneumophila
18h15-18h30 Barbara Weissenmayer, Irland
Analysis of the transcriptome of Legionella pneumophila under infection conditions using RNA.seq

Samedi 17 octobre 2009

Session 13: Gene regulation in the environment and the host
Modérateur : François Vandenesch, National Reference Center for Legionella and INSERM U851, Lyon, France
9h00-9h30 Klaus Heuner, Robert Koch Institut, Berlin, Germany
The Flagellar Regulon of Legionella pneumophila and the Expression of Virulence Traits
9h30-9h45 Tobias Sahr, France
Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila
9h45-10h00 Xavier Charpentier, USA
Parasexual behavior in response to genotoxic stress in Legionella pneumophila
10h00-10h15 Prix Alcora
10h15-10h45 Pause-café
Session 14: Cell biology - protozoa - macrophages
Modérateur: Elizabeth Hartland, University of Melbourne, Melbourne, Australia
10h45-11h15 Craig Roy, Yale University, USA
Establishment of a vacuole that supports Legionella pneumophila replication
11h15-11h45 Youssef Abu Kwaik, University of Louisville, Buffalo, USA
Exploitation of conserved eukaryotic pathways by L. pneumophila
11h45-12h15 Ralph Isberg, Tufts University, Boston, USA
Doubling up as a way to combat resilience
12h15-12h30 Conclusions