Theme of the conference
Organisers
Scientific program
Speakers
EWGLI meeting
(for collaborators only)
ALCORA Prize
Venue
Accommodation
Social program
Online registration opened
Call for abstracts
Students travel grants
Sponsors
Poster
Practical Information
Contact

Deadlines:

Preferential rates:
July 24th, 2009

Abstract submission:
July 24th, 2009

Applications for students travel grants:
July 24th, 2009

 
 
 
 
Logo design:
Marco LOMMA

SCIENTIFIC PROGRAM

Tuesday, October 13th, 2009

10:00 am-4:00 pm Ewgli meeting for Ewgli collaborators only, related to business aspects of the EWGLINET network and the transfer of the scheme to ECDC
2:00 pm-5:30 pm Registration
5:30 pm-6:00 pm Welcome addresses
Tony Pugsley, Senior Executive-Vice President for Scientific Affaire, Institut Pasteur, Paris, France
Carmen Buchrieser, Institut Pasteur, Paris, France
6:00 pm

Opening Session

Chair: Nicholas P. Cianciotto, Northwestern University Medical School,
Chicago, USA
  Barry Fields, Center of Disease Control, Atlanta, USA
Environmental approaches to the prevention of legionellosis
  Carol Joseph, Health Protection Agency, London, UK
Legionnaires' disease in Europe 1995 - 2008: Trends and challenges
  Jörg Hacker, Robert Koch Institut, Berlin, Germany
Legionella. A model organism for Genomics and Cellular Microbiology
7:30 pm Welcome Reception at Institut Pasteur

Wednesday, October 14th, 2009

8:30 am-10:15 am
Session 1: Epidemiology and Clinical aspects a) disease, diagnosis and treatment
Chair: Didier Che, Institut de Veille Sanitaire, Saint-Maurice, France
8:30am-9:00 am
Miguel Sabria, University of Barcelona, Spain
Clinical aspects of Legionnaires´Disease
9:00 am- 9:30 am
Paul H Edelstein, University of Pennsylvania, Philadelphia, USA
Antimicrobial therapy for Legionnaires' disease, still in need of improvement
9:30 am-9:45 am
Maria Luisa Pedro-Botet, Spain
Legionella pneumonia (LP) in immunosuppressed (IS) patients
9:45 am-10:00 am
Frances Graham, New Zealand
Changing Epidemiologic Trends of Legionellosis in New Zealand, 1979 - 2008
10:00 am-10:15 am
Lauri Hicks, USA
Travel-Associated Legionnaires' Disease Surveillance in the United States, 25-28
10:15 am-10:45 am Coffee break
10:45 am-12:30 am
Session 2: Clinical aspects b) detection and subtyping

Chair: Jaana Kusnetsov, National Public Health Institute, Kuopio, Finland

10:45 am-11:15 am
Christian Lück, University Dresden, Germany
Microbiological diagnostic methods for the detection of Legionella infections
11:15 am-11:45 am
Timothy G. Harrison, Health Protection Agency, London, UK
Legionella pneumophila DNA sequence-based typing: progress, pitfalls and perspectives.
11:45 am-12:00 am
Patrick Yang, USA
Evaluation of a fully integrated point-of-testing system for the detection of viable Legionella pneumophila
12:00 am-12:15 am
Valeria Gaia, Switzerland
MALDI-TOF MS based protein mass fingerprinting: a rapid and reliable method for the identification of Legionella spp.
12:15 am-12:30 am
Jonas Lundström, Sweden
An improved and rapid sequence-based method for typing of Legionella pneumophila.
12:30 am-2:00 pm Lunch at Institut Pasteur
2:00 pm-3:30 pm Poster session
3:30 pm-5:15 pm
Session 3: Host - Microbe interactions: a) secretion systems and their substrates
Chair: Craig Roy, Yale University, USA
3:30 pm-3:55 pm Nicholas Cianciotto, North Western University, Chicago, USA
Type II protein secretion, siderophores, and pigment and what they mean for Legionella ecology and pathogenesis
3:55 pm-4:20 pm
Joseph Vogel, Washington University, St Louis, USA
The Legionella Dot/Icm type IVB secretion system
4:20 pm-4:45 pm
Antje Flieger, Robert Koch Institut, Berlin, Germany
Legionella pneumophila phospholipases and their mode of secretion
4:45 pm-5:00 pm
Li Xu Luo, USA
Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila effector
5:00 pm-5:15 pm
Mariella Lomma, France
Legionella pneumophila infections involve bacterial F-box proteins
5:15 pm-5:45 pm Coffee break
5:45 pm-7:00 pm
Session 4: Host - Microbe interactions:         
b) metabolism and virulence

Chair: Philippe Glaser, Institut Pasteur

5:45 pm-6:15 pm
Paul Hoffman, University of Virginia, Charlottesville, USA
The Legionella pneumophila Developmental Cycle: Role in Survival and Pathogenesis
6:15 pm-6:45 pm
Michele Swanson, Michigan University, USA
Legionella pneumophila virulence as a response to starvation
6:45 pm-7:00 pm
Yury Belyi, Russia
Cytotoxic glucosyltransferases of Legionella pneumophila
7:00 pm-8:30 pm
“Wine and cheese” party

Thursday, October 15th, 2009

8:45 am-10:00 am
Session 5: Immunology and host susceptibility

Chair: Ralph Isberg, Tufts University, Boston, USA

8:45 am-9:15 am
Tom Hawn, University Washington, Seattle, USA
Genetic variation & the pulmonary innate immune response to Legionella
9:15 am-9:30 am
Catarina Nogueira, USA
Dendritic cells rapidly undergo apoptosis to limit intracellular replication of Legionella pneumophila
9:30 am-9:45 am
Tatiana Silveira, Brazil
Pore formation is an Nlrc4/Ipaf inflammasome-dependent host cell response against virulent Legionella species that express flagellin
9:45 am-10:00 am
Juliane Lippmann, Germany
Type I IFNs mediate innate intracellular defense to Legionella pneumophila
10:00 am-10:30 am Coffee break
10:30 am-12:30 am
Session 6: Microbe - Environment interactions:        
a) cell biology, protozoa, biofilms
Chair: Agnes Ullmann, Institut Pasteur
10:30 am-11:00 am
Michael Steinert, University Braunschweig, Germany
Proteomic and functional characterization of outer membrane vesicles and Legionella-containing phagosomes
11:00 am-11:30 am
Hubert Hilbi, University of Zürich, Zürich, Switzerland
Signals produced and exploited by Legionella
11:30 am-12:00 am
Howard A. Shuman, Columbia University, New York, USA
Host determinants of Legionella infection
12:00 am-12:15 am
Sophie Pécastaings, France
A new method of producing Legionella pneumophila biofilms in a minimal medium
12:15 am-12:30 am
Rafael A. Garduno, Canada
Mature infectious forms (MIFs) and MIF-pellets as factors in the transmission of Legionnaires' disease
12:30 am-2:00 pm Lunch at Institut Pasteur
1:30 pm-3:00 pm Poster session
3:00 pm-4:30 pm
Session 7: Microbe - Environment interactions:
b) detection in natural and artificial reservoirs - survival, persistence
Chair: Yann Héchard, Université de Poitiers, France
3:00 pm-3:30 pm
Paola Borella, Modena University, Italy
Risk factors for Legionella contamination and persistence in potential sources of infection
3:30 pm-4:00 pm
Shin-ichi Yoshida, Kyushu University, Fukuoka, Japan
Legionella physiology in the environment
4:00 pm-4:15 pm
Rinske Valster, Netherlands
Detection of hosts for Legionella pneumophila in freshwater by enrichment of free-living protozoa in a biofilm-batch system
4:15 pm-4:30 pm
Sharon G. Berk, USA
Long-term survival of novel amoeba-associated bacteria compared with Legionella pneumophila under conditions of hydration and desiccation
4:30 pm-4:50 pm Coffee break
4:50 pm-6:05 pm

Session 8: Legionella prevention and control

Chair: Maria Luisa Ricci, Istituto Superiore di Sanita, Rome, Italy
4:50 pm-5:20 pm
Katherine Ricketts, Health Protection Agency, London, UK
Travel associated Legionnaires' disease in Europe 2008: reporting and response
5:20 pm-5:50 pm
Janet Stout, Special pathogens Unit, Pittsburg, USA
Legionella and the Conundrum of Low Risk Buildings: A Very Modest Proposal
5:50 pm-6:05 pm
John V. Lee, UK
An international trial of quantitative PCR for monitoring Legionella in artificial water systems
7:30 pm Gala dinner

Friday, October 16th, 2009

8:30 am-10:15 am
Session 9: Epidemiology: a) nosocomial infections and Legionella control in hospitals

Chair: Paul H. Edelstein, University of Pennsylvania Medical Center,
Philadelphia, USA

8:30 am-9:00 am
Loreen Herwaldt, University of Iowa Hospital, USA
Decontamination of Hospital Water Supplies: A Review of the Literature and the University of Iowa's Experience
9:00 am-9:30 am
Jérôme Etienne, University Lyon, France
Nosocomial infections, Legionella strain characterization and host-related risk factors
9:30 am-9:45 am
Mireia Coscollá, Spain
Multiple Legionella strains infection detected by sequence analysis directly from respiratory samples
9:45 am-10:00 am
Claressa Lucas, USA
The impact of monochloramine introduction on Legionella colonization in a hospital potable water system.
10:00 am-10:15 am
Susanne Surman-Lee, UK
Lessons learnt from investigating hospital-acquired legionellosis and the remedial actions in England.
10:15 am-10:45 am Coffee break
10:45 am-12:30 pm
Session 10: Epidemiology:
b) outbreaks and population genetics and taxonomy

Chair: Carmen Pelaz, Instituto de Salud Carlos III, Madrid, Spain

10:45 am-11:15 am
Antoni Plasencia, Public Health Catalonia, Spain
Managing public health crises: from legionellosis to pandemic influenz
11:15 am-11:45 am
Rod Ratcliff, Infectious disease laboratories, Adelaide, Australia
Ecological diversity within Legionella
11:45 am-12:00 am
Sebastian Crespi, Spain
Legionellosis Prevention Guidelines: Better, but Not Well
12:00 am-12:15 am
Igor S. Tartakovskiy, Russia
From large community outbreak in Verhnaya Pyshma to effective prevention of legionellosis in Russia.
12:15 am-12:30 am
Joana Costa, Portugal
Molecular evolution of dotA gene in Legionella pneumophila: contribution of natural environmental isolates.
12:30 am-2:00 pm Lunch at Institut Pasteur
2:00 pm-3:30 pm Poster Session
3:30 pm-4:45 pm
Session 11: Genomics and Comparative genomics
Chair: Howard Shuman, Columbia University, New York, USA
3:30 pm-4:00 pm
Carmen Buchrieser, Institut Pasteur, Paris, France
Legionella pneumophila and Legionella longbeachae pathogenesis: new insights gained form comparative and functional genomics
4:00 pm-4:15 pm
Brian Shelton, USA
Polymorphic loci in Legionella pneumophila serogroup 1
4:15 pm-4:30 pm
Olga Shevchuk, Germany
Proteomic analysis of a Legionella-containing phagosome in Dictyostelium
4:30 pm-4:45 pm
Ivan Moszer, France
Genome re-annotation and web resources for Legionella pneumophila species
4:45 pm-5:15 pm Coffee break
5:15 pm-6:45 pm
Session 12: Functional genomics
Chair: Michele Swanson, University of Michigan Medical Center, Ann Arbor, USA
5:15 pm-5:45 pm
Elisabeth Hartland, University Melbourne, Australia
Hidden protein treasures revealed in the Legionella genome
5:45 pm-6:00 pm
Frank Schuren, Netherlands
Epidemiological genome analysis of a large Dutch Legionella pneumophila strain collection identifies five markers highly correlated with pathogenic strains
6:00 pm-6:15 pm
Tamara O'Connor, USA
Solving functional redundancy amongst effectors of the bacterial pathogen, Legionella pneumophila
6:15 pm-6:30 pm
Barbara Weissenmayer, Irland
Analysis of the transcriptome of Legionella pneumophila under infection conditions using RNA.seq

Saturday, October 17th, 2009

9:00 am-10:15 am
Session 13: Gene regulation in the environment and the host
Chair: François Vandenesch, National Reference Center for Legionella and INSERM U851, Lyon, France
9:00 am-9:30 am
Klaus Heuner, Robert Koch Institut, Berlin, Germany
The Flagellar Regulon of Legionella pneumophila and the Expression of Virulence Traits
9:30 am-9:45 am
Tobias Sahr, France
Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila
9:45 am-10:00 am
Xavier Charpentier, USA
Parasexual behavior in response to genotoxic stress in Legionella pneumophila
10:00 am-10:15 am
Alcora prize
10:15 am-10:45 am Coffee break
10:45 am-12:30 am
Session 14: Cell biology - protozoa - macrophages
Chair: Elizabeth Hartland, University of Melbourne, Melbourne, Australia
10:45 am-11:15 am
Craig Roy, Yale University, USA
Establishment of a vacuole that supports Legionella pneumophila replication
11:15 am-11:45 am
Youssef Abu Kwaik, University of Louisville, Buffalo, USA
Exploitation of conserved eukaryotic pathways by L. pneumophila
11:45 am-12:15 am
Ralph Isberg, Tufts University, Boston, USA
Doubling up as a way to combat resilience
12:15 am-12:30 pm
Closing remarks