programme scientifique
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Workshop "Systems Biology for Beginners"
8avril 2008 de 14h à 17h
organisé by Philippe GLASER, Institut Pasteur, Paris, France et Benno SCHWIKOWSKI, Institut Pasteur, Paris, France
33 places disponibles. Frais d'inscription : 30 € TTC. Inscription spécifique non incluse dans les frais d'inscription à la conférence.
Pour vous inscrire, télécharger le formulaire d'inscription et envoyer le par courrier à :
Institut Pasteur
CIS - Gestion des Colloques
28 rue du Docteur Roux
75724 Paris cedex 15
ou par fax: + 33 1 40 61 37 21
Mardi 8 avril 2008 |
| 13h30-17 h30 |
Accueil participants |
| 14h00-17h00 |
Atelier “Systems Biology for beginners”
organisé par Philippe GLASER, Institut Pasteur, Paris, France et Benno SCHWIKOWSKI, Institut Pasteur, Paris, France |
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| Discours de bienvenue |
| Bernard Dujon, Senior Executive-Vice President for Scientific Affaire, Institut Pasteur, Paris, France |
| Carmen BUCHRIESER, Institut Pasteur, Paris, France |
| Discours d'ouverture |
Modérateur : Jörg HACKER, Robert Koch-Institut, Berlin, Germany |
Martin J. Blaser, New York University School of Medicine, New York, USA
The extensive and changing conversations between Helicobacter pylori and human cells |
Pascale Cossart, Institut Pasteur, France
Listeria monocytogenes : RNA lessons from the genome |
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| 19h30 |
Cocktail de bienvenue à l'Institut Pasteur |
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Mercredi 9 avril 2008 |
8h30-10h25 |
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| 8h30-8h55 |
| 8h55-9h20 |
| 9h20-9h45 |
| 9h45-10h05 |
| 10h05-10h25 |
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Session 1 : Host - Microorganism Interactions: a) Pathogens |
Modérateur : Tony Pugsley, Institut Pasteur, Paris, France |
Dirk Bumann, University of Hannover, Germany
Systems Biology of Salmonella infection |
Ulla Bonas, Martin-Luther University, Halle, Germany
New insights into how the phytopathogen Xanthomonas manipulates the host |
Andrew Camilli, Tufts University, Boston, USA
Genetic Analysis of the Transmissible State of Vibrio cholerae |
Thomas Meyer, Max Planck Institute for Infection Biology, Berlin, Germany
Systematic dissection of host cell function during infection |
Sigrid De Keersmaecker, Ctre of Microbial & Plant Genetics, Leuven, Belgium
Towards systems biology, the Salmonella typhimurium luxs/ai-2 related pathway as a case study |
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| 10h25-11h00 |
Pause-café |
11h00-12h35 |
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11h00-11h25 |
| 11h25-11h50 |
11h50-12h15 |
12h15-12h35 |
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Session 1 : Host - Microorganism Interactions: a) Pathogens |
Modérateur : Birgitta Henriques Normark, Karolinska Institute Stockholm, Stockholm, Sweden |
Eliora Ron, University of Tel Aviv, Israel
Systemic E. coli infections – what can we predict from genomics? |
Stephen Lory, Harvard University, Boston, USA
Insights into the evolution of virulence in Pseudomonas aeruginosa: covering all bases |
Roland Brosch, Institut Pasteur, Paris, France
The tubercle bacilli : Molecular determinants of pathogenicity and attenuation |
Christoph Dehio, University of Basel, Basel, Switzerland
Comparative and functional genomic analysis of Bartonella identifies type iv secretion systems as host adaptability factors |
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| 12h35-14h00 |
Déjeuner à l'Institut Pasteur |
| 14h00-15h30 |
| Session Poster |
Presentations Entreprises |
14h-14h30 : Applied Biosysrems
Paolo Vatta - Comparative Whole Genome Sequencing using SOLiD™ System |
14h30-15h : Cogenics
Marcel de Leeuw - Putting Next Generation sequencing of microbial genomes to work |
15h-15h30 : Roche Diagnostics
Andread Tauch -
Ultrafast pyrosequencing of the Human pathogens Corynebacterium urealyticum and Corynebacterium |
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| 15h30-17h05 |
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| 15h30-15h55 |
| 15h55-16h20 |
| 16h20-16h45 |
| 16h45-17h05 |
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Session 2 : Host - Microorganism Interactions: b) Symbionts, Commensals |
Modérateur : Peter SEBO, Czech Academy of Science, Prague, Czech Republic |
Oded Beja, Technion - Israel Institute of Technology, Haifa, Israel
Metagenomics of viral 'photosynthesis' |
Dusko Ehrlich, INRA, Jouy en Josass, France
Metagenomics of the human digestive tract – insights into commensal bacteria |
Richard FFrench-Constant, University of Bath, United Kingdom
Rapid Virulence Annotation of Bacterial Genomes: Lessons from the insect pathogen Photorhabdus |
Sascha Stoll, University of Wüerzburg, Wüerzburg, Germany
The transcriptome of the endosymbiont Blochmannia floridanus in the different life stages of its holometabolous host |
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| 17h05-17h35 |
Pause-café |
| 17h35-18h50 |
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17h35-18h00 |
18h00-18h25 |
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Session 3 : Host Genomics and Vaccines |
Modérateur : Agnès ULLMANN, Institut Pasteur, Paris, France |
Catharina Svanborg, University of Lund, Sweden
Innate immune response genetics and susceptibility to urinary tract infection |
Philippe Sansonetti, Institut Pasteur, France
How Shigella hijacks host-cell gene transcription and signalling pathways to modulate the innate immune response |
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| 18h30-20h00 |
Wine and Cheese |
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Jeudi 10 avril 2008 |
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| 8h30 - 8h55 |
| 8h55 - 9h20 |
| 9h20 - 9h45 |
| 9h45 - 10h05 |
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Session 4 :New Technologies – What are the Results |
Modérateur : Antoine DANCHIN, Institut Pasteur, Paris, France |
Michael Hecker, University of Greifswald, Greifswald, Germany
Towards the entire proteome of gram-positive bacteria |
Amos Bairoch, Swiss Institute of Bioinformatics, Geneva, Switzerland
UniProtKB and microbial proteomes: status and future developments |
Julian Parkhill, Sanger Center, Cambridge, United Kingdom
Variation detection in highly monomorphic bacteria using new sequencing technologies |
Trent Northen, The Scripps Research Institute, La Jolla, United States
High Throughput Mass Spectrometry Based Metabolomic and Enzymatic Assays for Functional Genomics |
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| 10h05-10h40 |
Pause-café |
| 10h40-12h15 |
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| 10h40-11h05 |
| 11h05-11h30 |
| 11h30-11h55 |
| 11h55-12h20 |
| 12h20-12h40 |
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Session 5 : Functional Genomics |
Modérateur : Brendan WREN, London, United Kingdow |
Susan Gottesman, Nat. Cancer Inst., Bethesda, USA
Small RNAs and E. coli regulatory circuits |
Peer Bork, EMBL, Heidelberg, Germany
Predicting biological function at different scales |
Tracy Palmer, University of Dundee, Dundee, United Kingdom
Functional genomic analysis of protein secretion in Streptomyces species |
Mariagrazia Pizza, Novartis Vaccines, Italy
Microbial genomes as basis of vaccine discovery: the Meningococcus B challenge |
Athanasios Typas, University of California at San Francisco, San Francisco, USA
The first high-throughput system for quantitatively assessing genetic interactions in bacteria |
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| 12h40-14h00 |
Déjeuner à l'Institut Pasteur |
| 14h00-15h30 |
Session poster |
| 15h30-16h45 |
| |
| 15h30-15h55 |
| 15h55-16h20 |
| 16h20-16h45 |
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Session 6 : Microbial Metagenomics |
Modérateur : Didier MAZEL, Institut Pasteur, Paris, France |
Jean Weissenbach, Genoscope, Paris, France
Mining metagenomes |
Victor de Lorenzo, Centro Nacional de Biotecnología, Madrid, Spain
Debugging and reconstructing regulatory networks of Pseudomonas putida for environmental release |
George Weinstock, Baylor College, Huston, USA
Approaching the Human Microbiome |
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| 16h45-17h10 |
Pause-café |
| 17h10-18h20 |
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| 17h10-17h35 |
| 17h35-18h00 |
| 18h00-18h20 |
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Session 6 : Microbial Metagenomics |
Modérateur : Hilde DE REUSE, Institut Pasteur, Paris, France |
Karl O. Stetter, University of Regensburg, Germany
The Hyperthermophilic Archaea |
Virginia Armbrust, University of Washington, USA
Life in the sea: new insights from diatom genomes |
Lena Tasse, INSA Toulouse, Toulouse, France
Screening of the human intestinal microbiota for the discovery of new enzymes specific for fiber degradation |
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| 20h00 |
Dîner de gala |
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Vendredi 11 avril 2008 |
| 8h30-10h05 |
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| 8h30-8h55 |
| 8h55-9h20 |
| 9h20-9h45 |
| 9h45-10h05 |
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Session 7 : Computational, Structural Genomics and Systems Biology |
Modérateur : Benno SCHWIKOSKY, Institut Pasteur, France |
Russel L Finley Jr, Wayne State University, Detroit, USA
Generating protein interaction maps for pathogens using yeast two-hybrid |
Jörg Stelling, ETH Zürich, Switzerland
Systems analysis of signal transduction pathways |
Fiona Brinkman, Simon Fraser University, Burnaby, Canada
Insights into the evolution of pathogens using improved bioinformatics approaches |
Alexei Savchenko, University of Toronto, Toronto, Canada
Genomewide structural and biochemical annotation of uncharacterised proteins from pathogenic bacteria |
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| 10h05-10h35 |
Pause-café |
10h35-12h30 |
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| 10h35-11h00 |
| 11h00-11h25 |
| 11h25-11h50 |
| 11h50-12h30 |
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Session 8 : Comparative Genomics and Evolution |
Modérateur : Agnès LABIGNE, Institut Pasteur, Paris, France |
Erick Denamur, Medical Faculty Xavier Bichat, Paris, France
Population phylogenomics of the Escherichia coli species |
Carmen Buchrieser, Institut Pasteur, Paris, France
Comparative genomics of Legionella pneumophila and Legionella longbeachae, two human pathogens that coevolved with protozoa |
Tim Stinear, Monash University, Victoria, Australia
Insight into tuberculosis and Buruli ulcer from the complete genome sequence of Mycobacterium marinum |
| Pathogenomics PhD award |
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| 12h30-14h00 |
Déjeuner à l'Institut Pasteur |
| 14h00-15h00 |
Session poster |
| 15h00-16h40 |
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| 15h00-15h25 |
| 15h25-15h50 |
| 15h50-16h15 |
| 16h15-16h40 |
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Session 8 : Comparative Genomics and Evolution |
Modérateur : Xavier Nassif, Necker Hospital, Paris, France |
Hilde De Reuse, Institut Pasteur, Paris, France
Nickel trafficking in the gastric pathogen Helicobacter pylori |
Uri Gophna, University of Tel Aviv, Israel
Complexity, connectivity, and the fate of laterally acquired genes |
Mark Pallen, The University of Birmingham, Birmingham, United Kingdom
Escherchia coli: Pathogenomics of a model organism |
Ben Adler, Monash University, Victoria, Australia
What can we learn from comparative genomics of Leptospira species? |
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| Récompense du meilleur poster |
| Discours de clôture |
| Frank Kunst, Institut Pasteur, France |
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