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Programme scientifique
(mis à jour 09.11.06 18:32)

Mercredi 15 novembre 2006


13h00 Accueil des participants
14h00-15h00

Immunity and tolerance by DC targeting in vivo
Keynote address: Michel C. Nussenzweig, Rockefeller University, New York, USA

15h00-18h30

Session 1 : Impact of the Flora on Development and Homeostasis
Modérateur : Lora Hooper, University of Texas Southwestern Medical Center, Dallas, USA
Geneviève Milon, Institut Pasteur, Paris, France

Margaret McFall-Ngai, University of Wisconsin, Madison, USA - A common language of mutualism and pathogenesis: development of the Euprymna scolopes/Vibrio fischeri model symbiosis.
Lora Hooper, University of Texas Southwestern Medical Center, Dallas, USA - Symbiotic bacteria direct expression of an intestinal bactericidal lectin.

Pause-café 16h00-16h30

Gerard Eberl, Institut Pasteur, Paris, France - Flora-induced organogenesis of intestinal lymphoid tissues.
Dennis L. Kasper, Harvard Medical School, Boston, USA - The symbiotic role of polysaccharides from intestinal flora in health and disease.
Philippe Sansonetti, Institut Pasteur, Paris, France - Rupture, invasion and inflammatory destruction of the intestinal barrier by invasive bacteria.
Maria T. Abreu, Mount Sinai School of Medicine, New York, USA - Inflammatory bowel diseases.

18h30 Cocktail de bienvenue dans le hall du CIS

Jeudi 16 novembre 2006


9h00-12h30

Session 2 : Genetic Models in Pathogenesis
Modérateurs : Christophe Antoniewski, Institut Pasteur, Paris, France
Bruno Lemaitre, CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette, France

Olivier Voinnet, CNRS, Institut de Biologie Moléculaire des Plantes, Strasbourg, France - Antiviral RNA silencing in eucaryotes.
Frederick M. Ausubel, Harvard Medical School/Massachusetts General Hospital, Boston, USA -
Use of C. elegans to study bacterial virulence and to identify antimicrobial compounds.
Jonathan Ewbank, Université de la Méditerranée, Centre d'Immunologie de Marseille-Luminy, France - Serratia marcescens
and C. elegans.

Pause-café 10h30-11h00

Bruno Lemaitre, CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette, France - Sensing and bacterial tolerance at the gut epithelium surfaces of Drosophila.
Sara Cherry (remplace Norbert Perrimon) , University of Pennsylvania, Philadelphia, USA - Using Drosophila to uncover host factors involved in pathogenesis.
Wilbert Bitter, Vrije University Medical Centre, Amsterdam, The Netherlands - Mycobacterium marinum and zebrafish: a useful model for tuberculosis.

12h30-14h00 Photo de groupe + Déjeuner (Espace Congrès)
14h00-17h30

Session 3 : Microbial Interference with Priming the Host Response
Modérateurs : Matthew Albert, Institut Pasteur, Paris, France
Stephen Hedrick, University of California San Diego, La Jolla, USA

Joachim Kurtz, Eidgenössische Technische Hochschule , Zurich, Switzerland - An evolutionary approach to immunological priming in invertebrate hosts.
Eric Pamer, Memorial Sloan-Kettering Cancer Center, New York, USA - Immunity to Aspergillus fumigatus.
Maria Yazdanbakhsh, Leiden University, The Netherlands - Immune regulation by parasitic helminths.

Pause-café 15h30-16h00

Thomas Areschoug (remplace Siamon Gordon) , Sir William Dunn School of Pathology, Oxford, UK - Subversion of macrophage scavenger receptor A-mediated recognition and non-opsonic phagocytosis by pathogenic streptococci.
Raul Andino, University of California San Francisco, USA - Quasispecies structure and pathogenesis of RNA viruses.
Stephen M. Hedrick,University of California San Diego, La Jolla, USA - A microbe's view of the immune system.

19h00 Départ pour le dîner de gala (transferts en bus devant l'Institut Pasteur)

Vendredi 17 novembre 2006


9h00-12h30

Session 4 : How Microbes Sabotage the Adaptive Immune Response
Modérateurs : James Di Santo, Institut Pasteur, Paris, France
Anne O'Garra, National Institute for Medical Research, London, UK

Anne O'Garra, National Institute for Medical Research, London, UK - Regulation of IL-10 Expression by Dendritic Cells, Macrophages and T cells and Implications for Regulation of the Immune Response to Pathogens.
Cosima T. Baldari, University of Siena, Italy - Immune subversion by bacterial pathogens: the paradigms of Helicobacter pylori and Bacillus anthracis.
Kingston Mills, Trinity College Dublin, Ireland - Immune modulation by Bordetella pertussis and Fasciola hepatica.

Pause-café 10h30-11h00

Stipan Jonjic, University of Rijeka, Croatia - Down-regulation of NKG2D ligands by CMV.
Barry T. Rouse, University of Tennessee, Knoxville, USA - Treg and viral immunopathogenesis.
Graeme Alexander, Adenbrooke's Hospital, Cambridge, UK - T-regulatory cells and chronic viral hepatitis.

12h30-14h00 Déjeuner (Espace congrès)
14h00-17h30

Session 5 : Tolerance and Immunopathology
Modérateurs : Yasmine Belkaid, National Institutes of Health, Bethesda, USA
Michel Brahic
, Institut Pasteur, Paris, France

Yasmine Belkaid, National Institutes of Health, Bethesda, USA - Role and antigen specificity of natural Treg during parasitic infections.
Robert L. Hendricks, University of Pittsburgh, USA - CD8 T cells and latent virus: keeping the peace in sensory ganglia.
Anne Goldfeld, Harvard Medical School, Boston, USA - Immune suppression and response in human tuberculosis.

Pause-café 15h30-16h00

Silvia Gregori, San Raffaele Telethon Institute for Gene Therapy, Milan, Italy - Novel approaches to expand/induce regulatory T cells.
Peter Staeheli, University of Freiburg, Germany - Borna disease virus and neuropathology: brain damage by antiviral CD8 T cells.
Daniel Douek, National Institutes of Health, Bethesda, USA - HIV disease: fallout from mucosal catastrophe.

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