Immunity and tolerance by DC targeting in vivo
Keynote address: Michel C. Nussenzweig, The Rockefeller University, New York, USA

Session 1: Impact of the Flora on Development and Homeostasis
Chair persons: Lora Hooper, University of Texas Southwestern Medical Center, Dallas, USA
Geneviève Milon, Institut Pasteur, Paris, France

Margaret McFall-Ngai, University of Wisconsin, Madison, USA - A common language of mutualism and pathogenesis: development of the Euprymna scolopes/Vibrio fischeri model symbiosis.
Lora Hooper, University of Texas Southwestern Medical Center, Dallas, USA - Symbiotic bacteria direct expression of an intestinal bactericidal lectin.

Coffee-break 4.00 pm-4.30 pm

Gerard Eberl, Institut Pasteur, Paris, France - Flora-induced organogenesis of intestinal lymphoid tissues.
Dennis L. Kasper, Harvard Medical School, Boston, USA - The symbiotic role of polysaccharides from intestinal flora in health and disease.
Philippe Sansonetti, Institut Pasteur, Paris, France - Rupture, invasion and inflammatory destruction of the intestinal barrier by invasive bacteria.
Maria T. Abreu, Mount Sinai School of Medicine, New York, USA - Inflammatory bowel diseases.

Session 2: Genetic Models in Pathogenesis
Chair persons: Christophe Antoniewski, Institut Pasteur, Paris, France
Bruno Lemaitre, CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette, France

Olivier Voinnet, CNRS, Institut de Biologie Moléculaire des Plantes, Strasbourg, France - Antiviral RNA silencing in eucaryotes.
Frederick M. Ausubel, Harvard Medical School/Massachusetts General Hospital, Boston, USA - Use of C. elegans to study bacterial virulence and to identify antimicrobial compounds.
Jonathan Ewbank, Université de la Méditerranée, Centre d'Immunologie de Marseille-Luminy, France - Serratia marcescens and C. elegans.

Coffee-break 10.30 am-11.00 am

Bruno Lemaitre, CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette, France - Sensing and bacterial tolerance at the gut epithelium surfaces of Drosophila.
Sara Cherry (instead Norbert Perrimon), University of Pennsylvania, Philadelphia, USA - Using Drosophila to uncover host factors involved in pathogenesis.
Wilbert Bitter, Vrije University Medical Centre, Amsterdam, The Netherlands - Mycobacterium marinum and zebrafish: a useful model for tuberculosis.

Session 3: Microbial Interference with Priming the Host Response
Chair persons: Matthew Albert, Institut Pasteur, Paris, France
Stephen Hedrick, University of California San Diego, La Jolla, USA

Joachim Kurtz, Eidgenössische Technische Hochschule , Zurich, Switzerland - An evolutionary approach to immunological priming in invertebrate hosts.
Eric Pamer, Memorial Sloan-Kettering Cancer Center, New York, USA - Immunity to Aspergillus fumigatus.
Maria Yazdanbakhsh, Leiden University, The Netherlands - Immune regulation by parasitic helminths.

Coffee-break 3.30 pm-4.00 pm

Thomas Areschoug (instead Siamon Gordon) , Sir William Dunn School of Pathology, Oxford, UK - Subversion of macrophage scavenger receptor A-mediated recognition and non-opsonic phagocytosis by pathogenic streptococci.
Raul Andino, University of California San Francisco, USA - Quasispecies structure and pathogenesis of RNA viruses.
Stephen M. Hedrick,University of California San Diego, La Jolla, USA - A microbe's view of the immune sustem.

Session 4: How Microbes Sabotage the Adaptive Immune Response
Chair persons : James Di Santo, Institut Pasteur, Paris, France
Anne O'Garra, National Institute for Medical Research, London, UK

Anne O'Garra, National Institute for Medical Research, London, UK - Regulation of IL-10 Expression by Dendritic Cells, Macrophages and T cells and Implications for Regulation of the Immune Response to Pathogens.
Cosima T. Baldari, University of Siena, Italy - Immune subversion by bacterial pathogens: the paradigms of Helicobacter pylori and Bacillus anthracis.
Kingston Mills, Trinity College Dublin, Ireland - Immune modulation by Bordetella pertussis and Fasciola hepatica.

Coffee-break 10.30 am-11.00 am

Stipan Jonjic, University of Rijeka, Croatia - Down-regulation of NKG2D ligands by CMV.
Barry T. Rouse, University of Tennessee, Knoxville, USA - Treg and viral immunopathogenesis.
Graeme Alexander, Adenbrooke's Hospital, Cambridge, UK - T-regulatory cells and chronic viral hepatitis.

Session 5: Tolerance and Immunopathology
Chair persons: Yasmine Belkaid, National Institutes of Health, Bethesda, USA
Michel Brahic, Institut Pasteur, Paris, France

Yasmine Belkaid, National Institutes of Health, Bethesda, USA - Role and antigen specificity of natural Treg during parasitic infections.
Robert L. Hendricks, University of Pittsburgh, USA - CD8 T cells and latent virus: keeping the peace in sensory ganglia.
Anne Goldfeld, Harvard Medical School, Boston, USA - Immune suppression and response in human tuberculosis.

Coffee-break 3.30 pm-4.00 pm

Silvia Gregori, San Raffaele Telethon Institute for Gene Therapy, Milan, Italy - Novel approaches to expand/induce regulatory T cells.
Peter Staeheli, University of Freiburg, Germany - Borna disease virus and neuropathology: brain damage by antiviral CD8 T cells.
Daniel Douek, National Institutes of Health, Bethesda, USA - HIV disease: fallout from mucosal catastrophe.