Virus des Archaea hyperthermophiles

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David Prangishvili

 

Our research group is interested in exploration of the diversity of viruses on our planet. Specifically, we study viruses associated with the third domain of life, the Archaea, and isolate them from geothermally heated areas in various regions of active volcanism and active tectonics.

 

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Two dozens of unique hyperthermophilic viruses, all with DNA genomes (double- and singlestranded), have been discovered, isolated and characterized by us. The viruses infect Archaea, growing optimally above 80°C, and display morphologies that are different from those of viruses of Bacteria and Eukarya. The distinctiveness of morphologies of these viruses extends to their genome sequences and to the structures of the proteins they encode. Due to the unique morphological and genomic properties, the viruses from our collection are classified into 10 different viral families: Ampullaviridae, Bicaudaviridae, Clavaviridae, Fuselloviridae, Globuloviridae, Guttaviridae, Lipothrixviridae, Rudiviridae, Spiraviridae and Turriviridae.

 

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The results of our research lead to the notion that viruses of hyperthermophilic Archaea form a particular group in the viral world, different from viruses of Bacteria and Eukarya, and provide insights into basic problems of evolution of viruses and their interactions with host cells.

 

(For review, see : http://www.annualreviews.org/eprint/cIfKnKUShSmwfYCeqdau/full/10.1146/annurevmicro- 092412-155633)

Mis à jour le 20/02/2014

Contact

Unité de Biologie Moléculaire du Gène chez les Extrêmophiles (BMGE)

Bâtiment Fernbach 3eme étage

Institut Pasteur, 25 rue Dr. Roux

75724 Paris cedex 15 France

 

Secrétaire:

Ana Cova

ana.cova-rodrigues@pasteur.fr

01-45-68-88-30

01-45-68-88-34

Plan d'accès

 

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