Statistical and Mathematical Modeling in Biological Applications

The seminar series Statistical and Mathematical Modeling in Biological Applications (SaMMBA) features monthly lectures and discussions with leading modelers in biological sciences. Presentations are in English or French and target an interdisciplinary audience. Seminars are held on the campus of Institut Pasteur. Access is free. However, to enter the campus, one needs a badge that is obtained at the main gate in exchange of a piece of ID (passport, citizen card or driver licence). If you are planning to come from outside the campus, please contact Lulla Opatowski to have a badge ready when you arrive.

The SaMMBA seminars are financially supported by the ANRS and the region Ile de France through the “DIM Systèmes complexes”. 

For additional information about the series, contact the organizers: Pierre-Yves Böelle (UPMC, INSERM), Romulus Breban (Institut Pasteur), Vittoria Colizza (UPMC, INSERM)Judith Legrand (UPS), Lulla Opatowski (UVSQ, Institut Pasteur), Chiara Poletto (INSERM, UPMC), Virginie Supervie (INSERM, UPMC), Laura Temime (Cnam) and Elisabeta Vergu (INRA). To arrange to meet with an invited speaker, contact the host of that speaker. 

 

 

Next Lecture

Rebecca GRAIS

 

A heat-stable rotavirus vaccine: a Phase III trial in Niger. 

 

Abstract: 

Each year, rotavirus gastroenteritis is responsible for 37% of deaths due to diarrhea among children <5 years worldwide. Sub-Saharan Africa carries the largest burden of rotavirus-related mortality, but vaccination at scale in the region presents challenges. We conducted a randomized, placebo-controlled, trial in Niger to evaluate the efficacy of a live, oral rotavirus vaccine (BRV-PV, Serum Institute of India, Pvt Limited) to prevent severe rotavirus gastroenteritis (SRVGE).  Healthy infants were randomly assigned in a 1:1 ratio to receive three doses of vaccine or placebo at 6, 10, and 14 weeks of age. Episodes of gastroenteritis were assessed through active and passive surveillance and were graded with the use of the Vesikari scale. The primary endpoint was vaccine efficacy of three doses of vaccine vs. placebo against a first episode of laboratory-confirmed SRVGE from 28 days post-Dose 3. The primary results of this study will be discussed as well as additional challenges in vaccine trials in vulnerable populations.

 

Contact: Elisabeta Vergu

Tuesday, Oct 11th, 2016  

  12 noon -1 pm 

Institut Pasteur

Room Jean-Paul Aubert

 

 


Full Schedule 2016-2017

Raphaëlle Métras  Studying drivers for arboviral emergence: the case of Rift Valley fever in Mayotte*
Abstract

Wednesday, Sept 7th, 2016 

  12 noon-1 pm 

Room BIME 28-01-01A

Rebecca GRAIS A heat-stable rotavirus vaccine: a Phase III trial in Niger. Abstract

Wednesday, Oct 11th, 2016

12 noon -1 pm

Room Jean-Paul Aubert

 

 


Full Schedule 2015-2016

Henrik Salje

Use of mathematical modelling to reconstruct 60 years of chikungunya epidemiology in the Philippines

Abstract 

Wed, Sep 9th, 2015
  12 noon-1 pm 

Room Jean-Paul Aubert

 Anton Camacho 

The impact of dynamical modelling on public-health decisions made during the 2013-2015 Ebola outbreak

Abstract

Tuesday, Oct 6th, 2015 

  12 noon-1 pm 

Room BIME 28-01-01A

 

Marc LAVIELLE

Modeling and simulation of complex pharmacometric models: methods and tools

Abstract

Tue, Nov 3rd, 2015

  12 noon -1 pm 

Room BIME 28-01-01A

David CLAESSEN

Eco-evolutionary dynamics in spatially complex systems: from agro-ecology to the global ocean

Abstract

Tue, Dec 8th, 2015

12 noon -1 pm 

Room Jean-Paul Aubert

Jean-Pierre NADAL Modeling the contagion dynamics of the 2005 French riots Abstract

Tuesday, Jan 5th, 2016 

  12 noon -1 pm

Room BIME 28-01-01A

Mathieu ANDRAUD

Infectious diseases in pigs: from parameter estimation to dynamic models

Abstract

Tue, Feb 9th, 2016

  12 noon -1 pm 

Room BIME 28-01-01A

Marcel SALATHé Digital Epidemiology: Opportunities & Challenges of an Evolving Field Abstract

Wed, March 16th, 2016

  12 noon -1 pm 

Room BIME 28-01-01A

Daniela DE ANGELIS Prediction of antibiotic resistance in Staphylcoccus aureus Abstract

Tue, April 5th, 2016

  12 noon -1 pm 

Room Jean-Paul Aubert

Philippe LEMEY

 

Phylodynamic inference in viral outbreaks: power and limitations.

 

Abstract

Tue, May 3rd, 2016

  12 noon -1 pm 

Room BIME 28-01-01A

Hans BOGAARDS

Second-guessing the clustering of multiple HPV types: prospects of type replacement following mass immunization

Abstract

Tue, June 14th, 2016

  12 noon -1 pm 

Room BIME 28-01-01A

 


Full Schedule 2014-2015

 

Yamir MORENO

Dynamics of Interacting Diseases

Abstract 

Tue, Sep 9th, 2014
  12 noon -1 pm 

Chiara POLLETO

Modelling disease spatial spread and real time assessment of emerging pathogen events

Abstract

Wed, Oct 8th, 2014

  12 noon -1 pm 

Room BIME 28-01-01A

Gilles WAINRIB

Integrative network inference of gene expression data and applications to inflammatory bowel disease

Abstract

Tue, Nov 4th, 2014

  12 noon -1 pm 

Room Jean-Paul Aubert

Christian ROBERT

ABC methods for Bayesian model choice

Abstract

Tue, Dec 2nd, 2014

12 noon -1 pm 

Guillaume ACHAZ

The strange case of the Standard Neutral Model of molecular evolution: when, what and why

Abstract

Tue, Jan 13th, 2015 

  12 noon -1 pm

Room DUCLAUX RDC HAUT

Nicolas BACAER

Epidemic models and seasonality

Abstract

Tue, Feb 10th, 2015 

  12 noon -1 pm 

Room BIME 28-01-01A

Benoit PERTHAME

Kinetic models of chemotaxis and traveling pulses

Abtract

Tue, Mar 10th, 2015 

  12 noon -1 pm 

Room DUCLAUX RDC HAUT

Samuel ALIZON

Why does HIV harm its host? Clinical and epidemiological applications of virus phylogenies

Abstract

Tue, Apr 14th, 2015 

  12 noon -1 pm 

Room BIME 28-01-01A

Alan PERELSON

Mathematical modeling and the potential cure of HIV

Abstract

Wed, May 20th, 2015 

  12 noon -1 pm 

Room Retrovirus

Ron BROOKMEYER

Tracking the AIDS Epidemic: Estimating HIV Incidence

Abtract

Tue, June 2nd, 2015 

  12 noon -1 pm 

Pitié Salpétrière hospital,

Ecologie Cellulaire bldg.

 

  

 


Full Schedule 2013-2014

 

Alun LLOYD

Modeling novel strategies for controlling mosquito-borne diseases

Abstract 

Tue, Sep 24th, 2013 
  12 noon -1 pm 

Joseph DUREAU

 The Public Library of Models: an open source project towards social modeling

Abstract

Tue, Oct 8th, 2013 
  12 noon -1 pm 

Room Jules Bordet 

Julia GOG

Capturing the spread and evolution of influenza A

Abstract

Tue, Nov 5th, 2013 
  12 noon -1 pm 

Véronique THOMAS-VASLIN

Modélisation de la dynamique lymphocytaire T 

Abstract

Tue, Dec 10th, 2013 
  12 noon -1 pm 

Room Jean-Paul Aubert

Bernard
 CAZELLES

Wavelet analysis as a tool for considering non-stationarity in Epidemiology

Abstract

Tue, Jan 7th, 2014 
  12 noon -1 pm 

Room Jean-Paul Aubert

Jeremie GUEDJ

Modeling hepatitis C viral kinetic in the era of direct acting antiviral agents: review and perspectives

Abstract

Tue, Feb 11th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert

Peter WHITE

Tackling TB in the Age of Austerity: ensuring we use novel tools and approaches cost-effectively

Abstract

Tue, Mar 4th, 2014
  12:30 noon -1:30 pm

Room Jean-Paul Aubert  

Aurélien LATOUCHE

Regression modeling of the cumulative incidence function with missing causes of failure

Abstract

Tue, Apr 1st, 2014
  12 noon -1 pm

Room Jean-Paul Aubert 

Aaron KING

How to tell if the honeymoon is over: testing hypotheses about pertussis and its resurgence

Abstract

Tue, May 6th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert 

Carlo Giovanni CAMARDA

Modelling Social Contact Data: a smoothing constrained approach

Abstract

Tue, Jun 10h, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert 
Mis à jour le 08/09/2016