Bioinformatics tools for protein analysis

This one-week theoretical and practical course presents the use of bioinformatics tools for retriving, comparing, visualizing and analyzing protein sequences and structures.


Topics presented in the course include :


  • Sequence search in public databases (BLAST, PSI-BLAST, PHI-BLAST, HMMsearch).
  • Search from fuzzy patterns (Motif).
  • Sequence alignment (Align, Alix, ClustalW/X, 3D-Coffee).
  • Sequence profil and consensus from sequence subsets (Jalview, Logo,HMMer).
  • Logical operation, auto and crosscorrelation on sequence subsets (Evoluswap).
  • Search for signal peptide (SignalP), transmembrane domain (TMHMM), glycosylation sites, acylation sites, phosphorylation sites, functional signature (Prosite).
  • Secondary and tertiary structure prediction (Psi-pred, SCWRL, Swiss-model, Modeller, Robetta).
  • 3D-model validation (Colorado3D).
  • Display residue conservation over structure and analysis of residues programming for fold or function (Colorado3D).
  • Search for ligand binding sites (SUMO).


The program of the course organized the previous year can be downloaded to get detailed information on the general frame of the course; some topics and practical works may change each year, without altering the general aims and means of the course.


Program of the course Bioinformtics tools for protein analysis (PDF - 400 Ko)


Applicant should have a good practice in internet browsing and a bachelor grade (Master 1) or training in molecular biology and protein biochemistry. No skills in computer programming are required.

The committee of the course will evaluate applications.


Members of the Teaching Committee :


C. Parsot (Institut Pasteur),

Thierry Rose (Institut Pasteur).


Practical information


Title of the course Bioinformatics tools for protein analysis

Thierry Rose

Cellular immunogenetics unit

Institut Pasteur

Language English
Participants 16
Duration 1 week
Dates June 2 to 7, 2014
Closing date for application April 23, 2014

Institut Pasteur Diploma


Attending the course can be validated as "module d'école doctorale" for students registered at partner universities.



On line registration


Registration fees


Mis à jour le 10/06/2014

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