Pasteur course: Tuberculosis

LANGUE: ANGLAIS

 

This two-week course is intended for medical doctors, veterinarians, directors of clinical mycobacteriology laboratories, pharmacists and research scientists wishing to acquire an up to date knowledge on tuberculosis and the practice of molecular methods for diagnosis, drug susceptibility testing and epidemiology.

 

This full-time course is composed of lectures by international scientists and a practical training workshop. The language for lectures and the practical training is English. For people who might need it, help for French or Spanish speakers will be provided during the practical training.

 

Lectures will cover the global epidemiology of tuberculosis (TB); molecular epidemiology and evolution of Mycobacterium tuberculosis strains; immune responses during tuberculosis infection and disease; the human genetics of TB susceptibility; HIV co-infection; pediatric TB; mechanisms of antibiotic resistance, multidrug-resistance (MDR), extensive drug resistance (XDR); concepts and applications of rapid diagnosis and drug susceptibility tests (DST) in different settings; evaluation of the different methods using predictive values according to TB prevalence; anti-TB treatments including MDR-TB and XDR-TB; diagnosis of TB infection; whole genome sequencing; and non-tuberculosis mycobacteria.

 

The practical workshop will provide training for the different commercial tests approved for rapid diagnosis and DST using nucleic acid-based technologies: GenoType® MTBDR plus and MTBDRsl (HAIN Lifescience GmbH, Germany), and the GeneXpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA). Antibiotic gene targets will be sequenced to identify antibiotic resistance using a commercial sequencing platform and free software for DNA sequence analysis. There will also be an introduction to Whole Genome Sequencing and the use of software for detecting resistance-associated mutations in whole genome sequence data. Spoligotyping, MIRU/VNTR, and WGS analysis will be compared as tools for molecular epidemiology and contact tracing.

 

Speakers:

Laurent ABEL

Philip BUTCHER

Daniela CIRILLO

Christophe DELACOURT

Susan DORMAN

Francis DROBNIEWSKI       

Sébastien GAGNEUX

Brigitte GICQUEL

Philippe GLAZIOU

Jean Louis HERRMANN

Véronique JOLY

Dick VAN SOOLINGEN

Indira SOUNDIRAM

Steffen STENGER

Philip SUPPLY

Arnaud TREBUCQ

Nicolas VEZIRIS

Adam WITNEY

Ying ZHANG

Pasteur Bioinformatic Dept (C3BI)

 

 

Flyer annoucing the 2017 course

 

Download the program of the Tuberculosis course  - 2016-2017 Academic year

 

The committee of the course will evaluate applications.

 

Members of the Course Committee :

 

E. Coeffier (Institut Pasteur),

A. Fontanet (Institut Pasteur),

B. Gicquel (Institut Pasteur),

J.-L. Herrmann (Hôpital Saint-Louis, Paris),

C. Pierre-Audigier (Institut Pasteur),

V. Ponticelli (Institut Pasteur)

M. Sala (Institut Pasteur),

H. Takiff (Institut Pasteur),

A. Trebucq (UICTMR Paris),

H. Waxin (Institut Pasteur).

 

 

Practical information

 

Title of the course Tuberculosis
Director

Howard Takiff

Mycobacterial Genetics unit

Institut Pasteur

Honorary Director

Brigitte Gicquel

Mycobacterial Genetics unit

Institut Pasteur

Head of studies

Catherine Pierre-Audigier

Mycobacterial Genetics unit

Institut Pasteur

Organizing committee

Arnaud Fontanet

Brigitte Gicquel

Catherine Pierre-Audigier

Howard Takiff

Arnaud Trébucq

Language English
Participants 20
Duration 2 weeks
Dates

June 12-23, 2017

Closing date for application February 28, 2017
Diplomas

Institut Pasteur Diploma

 

ECTS for students registered in the Masters in Public Health from the Pasteur/ Cnam school of public health (Pasteur-Cnam).

Contact

enseignement@pasteur.fr

Application

On line registration

 

Registration fees

 
Mis à jour le 24/11/2016