Bioinformatics tools for protein analysis

This one-week theoretical and practical course presents the use of bioinformatics tools for retriving, comparing, visualizing and analyzing protein sequences and structures.


Topics presented in the course include:


  • Sequence search in public databases (BLAST, PSI-BLAST, PHI-BLAST, HMMsearch).
  • Search from fuzzy patterns (Motif).
  • Sequence alignment (Align, Alix, ClustalW/X, 3D-Coffee).
  • Sequence profile and consensus from sequence subsets (Jalview, Logo,HMMer).
  • Logical operation, auto and crosscorrelation on sequence subsets (Evoluswap).
  • Search for signal peptide (SignalP), transmembrane domain (TMHMM), glycosylation sites, acylation sites, phosphorylation sites, functional signature (Prosite).
  • Secondary and tertiary structure prediction (Psi-pred, SCWRL, Swiss-model, Modeller, Robetta).
  • 3D-model validation (Colorado3D).
  • Display residue conservation over structure and analysis of residues programming for fold or function (Colorado3D).
  • Search for ligand binding sites (SUMO).


The program of the course organized the previous year can be downloaded to get detailed information on the general content of the course; some topics and practical works may change each year, without altering the general aims and means of the course.


Program of the Bioinformtics tools for protein analysis course (PDF - 400 KB)


Applicants should have a good internet browsing skills and a Bachelors degree (Master 1) or training in molecular biology and protein biochemistry. No skills in computer programming are required.

The course committee will evaluate applications.


Members of the Teaching Committee:


C. Parsot (Institut Pasteur),

Thierry Rose (Institut Pasteur).


Practical information


Title of the course Bioinformatics tools for protein analysis

Thierry Rose

Cellular immunogenetics unit

Institut Pasteur

Language English
Participants 16
Duration 1 week

June 2nd to 7th, 2014

Closing date for application April 23, 2014

Institut Pasteur Diploma


Attending the course can be validated as a "module d'école doctorale (doctoral school module)" for students registered at partner universities.



On line registration

Registration fees


Updated on 10/06/2014

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