The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
This five-week intensive laboratory and lecture course presents advanced studies on the main themes in cellular and molecular immunology.
The main course comprises:
- Three weeks of state of the art practical laboratory sessions designed to introduce students to a research subject investigated by a variety of experimental approaches. Focus is on the characterization of two functions of the AID protein (Activation Induced Cytidine Deaminase) in B cells: isotypic switch and somatic hypermutation.
These roles of AID will be studied in B cells from wild type or AID-KO mice by FACS, ELISA analyses, reporter gene transfection assays, siRNA silencing, sequencing genes undergoing somatic hypermutation and real-time PCR. Some experiments are carried out in the BSL2+ facility of the Institut Pasteur Center for Human Immunology (CIH).
- Two weeks of lectures dealing with advanced studies on major topics in cellular and molecular immunology, such as: development of the immune system, lymphocyte differentiation, molecular basis of antigen recognition by B and T lymphocytes, repertoire selection, lymphocyte homeostasis, tolerance, cellular communication, immune responses, innate immunity and various aspects of immunopathology.
- Three days of thematic bibliography analysis seminars, given early January by groups of students and supervised by two senior scientists. These seminars are mandatory for students enrolled in Masters programs and optional for other participants.
The program of the course organized the previous year can be downloaded to get detailed information on the general content of the course; some topics and practical works may change each year, without altering the general aims and means of the course.
1) Since Type-2 Biosafety laboratory facilities will be used during the course, students’ updated tetanos and hepatitis B vaccination certificates are required.
2) The course requires personal work during evenings and weekends. Students should not make other commitments during that period. For instance, no hospital duties should be undertaken by MDs or Pharmacists during the course, including during the bibliography seminar week.
3) Candidates must have a good knowledge in biochemistry, molecular biology and genetics, as well as a good first year Masters level in immunology (or equivalent).
4) Students should have good knowledge of English to be able to understand full lectures, ask questions and deliver the bibliography analysis seminar in English. An understanding of French is useful, but not mandatory, for daily interactions.
5) Students not enrolled in a master 2 program of a partner university will take the final exam and finish the course on Saturday December 6th, 2014. Master 2 students will and take the final exam from January 5th to January 9th, 2015.
The course committee will evaluate applications.
Members of the Teaching Committee:
A. Alcover (Institut Pasteur),
P. A. Cazenave (Institut Pasteur/Université P. et M. Curie),
E. Coeffier (Institut Pasteur),
A. Freitas (Institut Pasteur),
C. Fridman* (Université Paris-Descartes),
F. Huetz (Institut Pasteur),
C. Parsot (Institut Pasteur),
A. Six* (Université P. et M. Curie),
M. Viguier* (Université Paris-Diderot),
A. Zider (Université Paris-Diderot).
* University Representatives
Title of the course
Lymphocyte cell biology unit - Institut Pasteur
Lymphocyte population biology unit - Institut Pasteur
Head of studies
Lymphocyte population biology unit - Institut Pasteur
5 +1 weeks
November 17th, 2014 to December 19th, 2014 and January 5th to 9th, 2015
Closing date for application
June 15, 2014
Institut Pasteur Diploma
Diplôme d'Université (DU) from Paris Diderot University for people registering at this university (registration fees ≈ €250).
Credits for a Masters degree for students registered at Parisian partner universities.
Attending conferences can be validated as a "module d'école doctorale (doctoral school module)" for students registered at partner universities.